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XB-PHENO-25405

Xla Wt + pqbp1 MO, Iwasaki Y and Thomsen GH (2014)

Experiment + Assay: Xla Wt + pqbp1 MO + NF13 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pqbp1 MO1 pqbp1 (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 13  
Anatomical Phenotypes: abnormal convergent extension , abnormal incomplete closing of the blastopore
Expression Phenotypes (2):
decreased amount tbxt.L expression in axial mesoderm
decreased amount tbxt.L expression in dorsal marginal zone
Source: Fig.S4
Article: XB-ART-49433, PubMed