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XB-PHENO-25546

Xla Wt + sobp MO, Tavares ALP et al. (2021)

Experiment + Assay: Xla Wt + sobp MO + NF16-18 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection sobp MO1 sobp (Xla)
NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 16 to NF stage 18  
Anatomical Phenotypes: increased width of neural plate
Expression Phenotypes (4):
decreased amount foxd3.L expression in neural crest
decreased amount krt12.4.L expression in epidermis
decreased amount six1.L expression in lateral preplacodal ectoderm
decreased amount sox2.L expression in neural plate
Source: Fig.4.D-G,T
Article: XB-ART-58292, PubMed