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XB-PHENO-25548

Xla Wt + sobpR651X, Tavares ALP et al. (2021)

Experiment + Assay: Xla Wt + sobpR651X + NF16-18 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(sobpR651X) sobp (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 16 to NF stage 18  
Expression Phenotypes (3):
decreased amount foxd3.L expression in neural crest
increased amount krt12.4.L expression in neuroectoderm
decreased amount six1.L expression in lateral preplacodal ectoderm
Source: Fig.4.Q-S,X
Article: XB-ART-58292, PubMed