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XB-PHENO-25550

Xla Wt + sobp, Tavares ALP et al. (2021)

Experiment + Assay: Xla Wt + sobp + NF28-33/34 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection sobp sobp (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28 to NF stage 33 and 34  
Anatomical Phenotypes: decreased size of the otic vesicle
Expression Phenotypes (5):
increased amount dlx5.L expression in otic vesicle
decreased amount dlx5.L expression in otic vesicle
increased amount pax2.L expression in otic vesicle
mislocalised pax2.L expression in otic vesicle
decreased amount six1.L expression in otic vesicle
Source: Fig.5.B,E,H,K
Article: XB-ART-58292, PubMed