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XB-PHENO-25551

Xla Wt + sobpR651X, Tavares ALP et al. (2021)

Experiment + Assay: Xla Wt + sobpR651X + NF28-33/34 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(sobpR651X) sobp (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28 to NF stage 33 and 34  
Expression Phenotypes (3):
decreased amount dlx5.L expression in otic vesicle
increased amount pax2.L expression in otic vesicle
decreased amount six1.L expression in otic vesicle
Source: Fig.5.C,F,I,L
Article: XB-ART-58292, PubMed