Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xla.Tg(tubb2b:ChIEF;Rno.elas:GFP)NXR | X. laevis | Xenopus neural (NBT/tubb2b) driving expression of blue light photoinducible channel rhodopsin (ChIEF... | ||
| Xla.Tg(CMV:H3K9ac-mintbody)Ueno | X. laevis | CMV promoter driving expression of of the epigenetic sensor, H3K9ac-mintbody (modification-specific ... | ||
| Xla.Tg(myl2:eGFP)Mohun | X. laevis | ~3kb myosin light chain (myl2, also known as xmlc2/mlc2) promoter driving enhanced GFP (eGFP) expres... | ||
| Xla.Tg(nkx2-5:GFP)Mohun | X. laevis | 8kb promoter of X. laevis NK2 homeobox 5 gene driving GFP | ||
| Xtr.hps6mGrngr | X. tropicalis | hps6 | No Privacy (NOP) embryos have a 10-bp deletion in the hps6 gene (a region from 468 to 477 counted fr... | |
| Xtr.insm2emHorb | X. tropicalis | insm2 | CRISPR knockout of insm2 (insulinoma-associated 2). Confirmed germline transmission. Custom mutant g... | |
| Xtr.lmnaemHorb | X. tropicalis | lmna | CRISPR knockout of lmna (lamin A/C).Confirmed germline transmission. Mutants carry a 14 bp deletion ... | |
| Xtr.mitfemHorb | X. tropicalis | mitf | CRISPR knockout of mitf (melanocyte inducing transcription factor). Current mosaic founders, not tes... | |
| Xtr.olig2emHorb | X. tropicalis | olig2 | CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. tropicalis. Confirme... | |
| Xtr.olig4emHorb | X. tropicalis | olig4 | CRISPR knockout of olig4 (oligodendrocyte transcription factor 4). Current mosaic founders, not test... | |
| Xtr.pou3f4emHorb | X. tropicalis | pou3f4 | CRISPR knockout of pou3f4 (POU class 3 homeobox 4). Current mosaic founders, not tested for germline... | |
| Xtr.prph2emHorb | X. tropicalis | prph2 | CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Confirmed germ line transmissi... | |
| Xtr.runx1em1Horb | X. tropicalis | runx1 | CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... | |
| Xtr.rxrbemHorb | X. tropicalis | rxrb | CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a... | |
| Xtr.rxrgemHorb | X. tropicalis | rxrg | Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... | |
| Xtr.map3k13emHorb | X. tropicalis | map3k13 | CRISPR knockout of map3k13 (mitogen-activated protein kinase kinase kinase 13). Confirmed germline t... | |
| Xtr.tlx3em1Horb | X. tropicalis | tlx3 | CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... | |
| Xtr.aif1lem1Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | |
| Xtr.ascl1emHorb | X. tropicalis | ascl1 | CRISPR knockout of ascl1(achaete-scute family bHLH transcription factor 1). Confirmed germline trans... | |
| Xtr.gdf1em1Horb | X. tropicalis | gdf1 | CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ... | |
| Xtr.erfemHorb | X. tropicalis | erf | CRISPR knockout of erf (ETS2 repressor factor). Confirmed germline transmission. Custom mutant gene... | |
| Xtr.foxc2em1Horb | X. tropicalis | foxc2 | CRISPR knockout of foxc2 (forkhead box C2). Confirmed germline transmission. Animals carry a 1 bp de... | |
| Xtr.frzb,frzb2emHorb | X. tropicalis | frzb2 | double CRISPR knockout of frzb (frizzled related protein ) and frzb2 (frizzled related protein 2). C... | |
| Xtr.glis3emHorb | X. tropicalis | glis3 | CRISPR knockout of glis3 (GLIS family zinc finger 3). Confirmed germline transmission. Custom mutant... | |
| Xtr.hpse2emHorb | X. tropicalis | hpse2 | CRISPR knockout of hpse2 (heparanase 2 (inactive)). Confirmed germline transmission. Custom mutant g... | |
| Xla.slc45a1emNXR | X. laevis | slc45a1.L | CRISPR knockout of Slc45a1 (solute carrier family 45 member 1 ). Screened for germline transmission.... | |
| Xla.olig3emHorb | X. laevis | olig3.S | CRISPR knockout of olig3 (oligodendrocyte transcription factor 3) ( olig3.S in Xlaevis). Current mos... | |
| Xla.pax3emHorb | X. laevis | pax3.L | CRISPR knockout of pax3 (paired box 3). Germ line transmission confirmed. animals carry a 11bp delet... | |
| Xla.pax7emHorb | X. laevis | pax7.L | CRISPR knockout of pax7 (paired box ). Germ line transmission confirmed. Animals carry a 4bp 9 bp o... | |
| Xla.pcntemHorb | X. laevis | pcnt.L | CRISPR knockout of pcnt (pericentrin ). Confirmed germline transmission. Custom mutant generated by ... | |
| Xla.pkd2emHorb | X. laevis | pkd2.L | CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Confirmed germ... | |
| Xla.aqp1emHorb | X. laevis | aqp1.L | CRISPR Knockout of aqp1.L and aqp1.S (Aquaporin1) Germline transmission confirmed. Mutation is a 1... | |
| Xla.ppp2r2aemHorb | X. laevis | ppp2r2a.L | CRISPR knockout of ppp2r2a (protein phosphatase 2 regulatory subunit B, alpha ). Current mosaic foun... | |
| Xla.eya1emHorb | X. laevis | eya1.L | CRISPR Knockout of eya1 (EYA transcriptional coactivator and phosphatase 1) .gRNAs target eya1.L and... | |
| Xla.fxr1emHorb | X. laevis | fxr1.L | CRISPR Knockout of fxr1(FMR1 autosomal homolog 1 ). Currently mosaic founders. Confirmed germline tr... | |
| Xla.prickle1emHorb | X. laevis | prickle1.L | CRISPR knockout of prickle1(prickle planar cell polarity protein 1). Confirmed germ line transmissio... | |
| Xla.gfi1emHorb | X. laevis | gfi1.L | CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor ).Confirmed germline tr... | |
| Xla.prph2emHorb | X. laevis | prph2.L | CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Current mosaic founders, not t... | |
| Xla.mitfemHorb | X. laevis | mitf.L | CRISPR knockout of mitf (melanocyte inducing transcription factor) Germ line transmission confirmed.... | |
| Xla.slc16a2emHorb | X. laevis | slc16a2.L | CRISPR knockout of slc16a2 (solute carrier family 16, member 2 (thyroid hormone transporter)). Germ ... | |
| Xla.sox10emHorb | X. laevis | sox10.L | CRISPR knockout of sox10 (SRY-box 10). Confirmed germline transmission in sox10.L (waiting for confi... | |
| Xla.mcidasemHorb | X. laevis | mcidas.L | CRISPR knockout of mcidas (multiciliate differentiation and DNA synthesis associated cell cycle prot... | |
| Xla.notch4emHorb | X. laevis | notch4.S | TALEN knockout of notch4 in X. laevis. THIS LINE is no longer available from the NXR | |
| Xla.olig2emHorb | X. laevis | olig2.L | CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. laevis. KOs both oli... | |
| Xla.wdpcpemHorb | X. laevis | wdpcp.L | CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Germ line transmissio... | |
| Xla.wnt11emHorb | X. laevis | wnt11.L | CRISPR knockout of wnt11 (Wnt family member 11), Confirmed germline transmission. Mutant line genera... | |
| Xtr.Tg(tubb2b:GFP)Amaya | X. tropicalis | Xenopus n-tubulin (tubb2b) promoter driving GFP. | ||
| Xtr.Tg(tubb2b:mapt-GFP)Amaya | X. tropicalis | 3481 bp N-beta-tubulin(tubb2b) promoter and 5'UTR driving expression of mapt-GFP fusion (tauGFP) in ... | ||
| Xtr.Tg(tubb2b:Hsa.ALPP;cryga:dsRed)Amaya | X. tropicalis | Neural expression of human placental alkaline phosphatase (Hsa.ALPP) driven by N-beta-tubulin (tubb2... | ||
| Xtr.Tg(pax6:GFP)Amaya | X. tropicalis | 3.6kb Xenopus paired box 6 ( pax6) promoter driving GFP. |
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