Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.bxemZimml | X. tropicalis | unknown | Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations. | |
| Xtr.mammZimml | X. tropicalis | unknown | Mutation affecting cardiac function identified in a screen for ENU-induced mutations at Mill Hill | |
| Xtr.askmZimml | X. tropicalis | unknown | Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in... | |
| Xtr.smad4mZimml | X. tropicalis | smad4 | Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... | |
| Xtr.unc45bmZimml | X. tropicalis | unc45b | Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. | |
| Xtr.mlomZimml | X. tropicalis | unknown | Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Map... | |
| Xtr.petmZimml | X. tropicalis | unknown | Homozygous mutants are completely paralyzed with no heartbeat. | |
| Xtr.supt5hmZimml | X. tropicalis | supt5h | Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... | |
| Xtr.atp7amZimml | X. tropicalis | atp7a | A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations... | |
| Xtr.ap3d1mZimml | X. tropicalis | ap3d1 | Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... | |
| Xtr.oc90mZimml | X. tropicalis | oc90 | Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... | |
| Xtr.tbxtemJcsm | X. tropicalis | tbxt | Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... | |
| Xla.npffr1.1emEXRC | X. laevis | npffr1.1.L | Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ). | |
| Xla.Tg(Xtr.dio3:GFP) | X. laevis | dio3 promoter driving GFP , generating using REMI transgenesis. DNA plasmid construct used part of ... | ||
| Xtr.tbxt.2em1Jcsm | X. tropicalis | tbxt.2 | Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... | |
| Xtr.tbxt.2em2Jcsm | X. tropicalis | tbxt.2 | Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... | |
| Xtr.tbxt,tbxt.2emJcsm | X. tropicalis | tbxt | Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... | |
| Xtr.PortsmouthEXRC | X. tropicalis | These are the main X.tropicalis stocks from the EXRC. This colony is outbred, primarily from the Nig... | ||
| Xtr.NigerianGrnger | X. tropicalis | A lab colony of Nigerian strain X tropicalis, descendants from wild caught frogs bred by Kirschner L... | ||
| Xla.runx1em(GFP)EXRC | X. laevis | runx1.L | CRISPR-Cas9 mediated insertion of IRES-GFP sequence into the 3'-UTR of runx1 gene, | |
| Xbo.Outbred | X. borealis | |||
| Xla.Tg(ror2:eGFP;cryga:GFP3)Ioka | X. laevis | DNA construct containing Ror2 promoter driving EGFP, γ-crystallin promoter driving GFP3 (Fu et al., ... | ||
| Xla.Tg(myl7:Gal4;UAS:Hsa.adprhl1-Xla.adprhl1)Mohun | X. laevis | This is a line with a human Xenopus adprhl1 fusion protein overexpressed in the heart by a myl7 Gal... | ||
| Xla.Tg(myl7:Gal4;UAS:adprhl1m)Mohun | X. laevis | The Xenopus form of the adprhl1 gene with silent mutations to escape regulatory repression in the h... | ||
| Xla.B Strain albino | X. laevis | The B strain is a line of inbred albino animals with estimated inbreeding of at least 10 generations... | ||
| Xla.B strain x J strain | X. laevis | A cross between the J strain and B strain. | ||
| Xla.outbredZoshoku | X. laevis | |||
| Xtr.tp53em_del1/+_Vlemx | X. tropicalis | tp53 | Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deleti... | |
| Xtr.tp53em_del2/+_Vlemx | X. tropicalis | tp53 | Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... | |
| Xla.outbredKXRCR | X. laevis | |||
| Xla.Tg(Dre.gfap:eGFP)Larra | X. laevis | zebrafish GFAP gene driving expression of in enhanced GFP in CNS including radial glial cells, neura... | ||
| Xla.Tg(Dre.gfap:mCherry-NTR)Larra | X. laevis | This transgenic line allows selective cell ablation in the CNS. NTR, Nitroreductase. Transgene was i... | ||
| Xla.hps4m | X. laevis | hps4.L | This periodic albino mutant of Xenopus laevis is a recessive mutant. Fukazawa et al 2020 showed that... | |
| Xtr.tp53em_del1/em_del2_Vlemx | X. tropicalis | tp53 | Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... | |
| Xla.kcptmFlc | X. laevis | kcp.L | One-cell stage Xenopus Xla.Tg(Cardiac-actin:GFP)Mohun embryos were microinjected with 1 ng TALEN mRN... | |
| Xtr.thratmShiyb | X. tropicalis | thra | This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... | |
| Xla.Tg(rho:hsa.rhosub_P23H) | X. laevis | Line with a human mutant form of rhodopsin with a Proline to Histidine substitution, which leads to ... | ||
| Xla.Tg(rho:Hsa.rhosub_T17M) | X. laevis | Line with a human mutant form of rhodopsin with a Threonine to Methionine substitution, under the X.... | ||
| Xla.Tg(rho:Hsa.rhosub_T4K) | X. laevis | Line with a human mutant form of rhodopsin with a Threonine to Lysine substitution, under the X.laev... | ||
| Xla.Tg(rho:hsa.rhodel) | X. laevis | Line with a human mutant form of rhodopsin with a Glutamine to termination substitution, under the X... | ||
| Xla.Tg(prrx1:CreER;CAGGs:lp-Cherry)Etnka | X. laevis | A stable double transgenic frog line that allows conditional labeling and tracing of limb connectiv... | ||
| Xla.adam13emNXR | X. laevis | CRISPR knockout of adam13 (ADAM metallopeptidase domain 13 ). Confirmed germline transmission. Anima... | ||
| Xtr.ahrem1NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT... | |
| Xtr.ahrem2NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. mutation: 7bp deleti... | |
| Xla.ahremNXR | X. laevis | ahr.L | Custom generated mutant made by NXR. Germ line transmission not yet confirmed. Contact NXR for detai... | |
| Xtr.aif1lem2Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | |
| Xtr.amhem2NXR | X. tropicalis | amh | CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant: 5b... | |
| Xtr.amhem3NXR | X. tropicalis | amh | CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant gen... | |
| Xtr.amhr2emNXR | X. tropicalis | amhr2 | CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... | |
| Xla.ar em1NXR | X. laevis | ar.L | CRISPR mutation of ar (androgen receptor). Mutation is confirmed as a 13bp deletion in ar.L ( AGTGTG... |
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