Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.hs6st1emNXR | X. tropicalis | hs6st1 | CRISPR knockout of hs6st1 (heparan sulfate 6-O-sulfotransferase 1) gene. Mutation not yet characteri... | NXR |
| Xla.dmrt1em4NXR | X. laevis | dmrt1.L dmrt1.S | Double X. levis CRISPR knockout line, targeting both dmrt1.S and dmrt1.L (doublesex and mab-3 relat... | NXR |
| Xla.ccdc69wem3NXR | X. laevis | 3rdof 3 CRISPR line targeting the male sex determination gene ccdc69w developed by the NXR. Germ lin... | NXR | |
| Xla.ccdc69wem2NXR | X. tropicalis | 2nd of 3 CRISPR line targeting the male sex determination gene ccdc69w developed by the NXR. Germ li... | NXR | |
| Xla.ccdc69wem1NXR | X. laevis | CRISPR line targeting the male sex determination gene ccdc69w. Germ line transmission confirmed . A... | NXR | |
| Xtr.cbsemNXR | X. tropicalis | cbs | Custom CRISPR generated by NXR, targeting the cbs (cystathionine-beta-synthase) gene, | NXR |
| Xbo.dmrt1em2NXR | X. borealis | 2ndor 2 X. borealis CRISPR line bred by NXR, targeting dmrt1 (doublesex and mab-3 related transcript... | NXR | |
| Xbo.dmrt1em1NXR | X. borealis | 1 or 2 X. borealis CRISPR line bred by NXR, targeting dmrt1 (doublesex and mab-3 related transcripti... | NXR | |
| Xtr.snai2em3NXR | X. tropicalis | snai2 | 3rd CRISPR knockout line targeting snai2 (snail family zinc finger 2) in X. tropicalis. Germ line tr... | NXR |
| Xtr.snai2 em2NXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | NXR |
| Xtr.syngap1 emNXR | X. tropicalis | syngap1 | CRISPR line targeting syngap1 (). Not screened for mutation or germ line transmission yet. Contact t... | NXR |
| Xla.tcf3emNXR | X. laevis | tcf3.L | X. laevis CRISPR line targeting tcf3.L (transcription factor 3). Line in development. Contact NXR f... | NXR |
| Xla.tbx21emNXR | X. laevis | tbx21.L tbx21.S | double CRISPR KO line targeting tbx21.L and tbx21.S in X. laevis. germ line transmission snd mutatio... | NXR |
| Xla.tap2emNXR | X. laevis | tap2.L tap2.S | X. laevis CRISPR line targeting tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP), a... | NXR |
| Xla.tap1emNXR | X. laevis | tap1.L | X. laevis CRISPR line targeting tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP), a... | NXR |
| Xla.velo1emNXR | X. laevis | velo1.L | X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized . Germ lin... | NXR |
| Xla.wnt3em2NXR | X. laevis | wnt3.L | X. laevis CRISPR line targeting wnt3.L (Wnt family member 3). Germ line transmission not yet confirm... | |
| Xla.wnt3em1NXR | X. laevis | wnt3.S | X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission not yet confirm... | NXR |
| Xtr.wnt3em1NXR | X. tropicalis | wnt3 | CRISPR line targeting wnt3 (Wnt family member 3). Germ line transmission not yet confirmed, mutation... | NXR |
| Xtr.xbp1em2NXR | X. tropicalis | xbp1 | 2nd X. tropicalis CRISPR line for xbp1 (X-box binding protein 1, a gene assocaited with Major Affec... | NXR |
| Xla.scanwemNXR | X. laevis | CRISPR knock out of the male sex determining gene, scan-w. Animals carry a 20bp deletion in scanw. ... | NXR | |
| Xtr.ripply3em2NXR | X. tropicalis | ripply3 | 2nd of 2 ripply3 lines at the NXR, CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ l... | NXR |
| Xtr.nagluem3NXR) | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). 3rd of 3 X.tropicalis mutant lines. Germ ... | NXR |
| Xtr.eomesem2Horb | X. tropicalis | eomes | 2nd CRISPR knockout of eomes (eomesodermin), carrying a 4bp deletion. Custom mutant generated by Ho... | |
| Xla.prkdcem2NXR | X. laevis | prkdc.L | CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission confi... | NXR |
| Xtr.nagluem2NXR | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals... | NXR |
| Xtr.nagluem1NXR | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase) gene. Germ line transmission confirmed. An... | NXR |
| Xla.rag2emNXR | X. laevis | rag2.L | CRISPR knockout of rag2 (recombination activating 2). Germ line transmission confirmed. Animals carr... | NXR |
| Xla.foxn1em2NXR | X. laevis | CRISPR knockout of foxn1 (forkhead box N1). Germ line transmission confirmed, F1s established. Anima... | NXR | |
| Xla.rykemNXR | X. laevis | ryk.S | CRISPR knockout of ryk.S (receptor like tyrosine kinase S homeolog). Germline transmission not yet c... | NXR |
| Xtr.foxp3em2NXR | X. tropicalis | foxp3 | CRISPR knockout of foxp3 (forkhead box P3). Germ line transmission confirmed. Animals carry a 17 bp ... | |
| Xtr.mtnr1aemNXR | X. tropicalis | mtnr1a | CRISPR knock out of mtnr1a (melatonin receptor 1A ) in X. tropicalis. germ line transmission confirm... | NXR |
| Xtr.six1em2NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... | NXR |
| Xtr.zmym4emNXR | X. tropicalis | zmym4 | CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi... | NXR |
| Xtr.zeb2emNXR | X. tropicalis | zeb2 | CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... | NXR |
| Xtr.ywhazemNXR | X. tropicalis | ywhaz | CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). Ge... | NXR |
| Xtr.xbp1emNXR | X. tropicalis | xbp1 | CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... | NXR |
| Xla.baz1bemNXR | X. laevis | baz1b.L | TALENs knockout of baz1b (bromodomain adjacent to zinc finger domain 1B ) aka 'wstf', a gene associa... | |
| Xla.wnt11bemNXR | X. laevis | wnt11b.L | CRISPR knockout of wnt11b in X laevis. Germline transmission confirmed. F2 animals carry a 13bp de... | NXR |
| Xtr.wnt11bemNXR | X. tropicalis | wnt11b | X. tropicalis CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), ... | NXR |
| Xtr.wbp11emNXR | X. tropicalis | wbp11 | CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... | NXR |
| Xtr.vwa2emNXR | X. tropicalis | vwa2 | CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... | |
| Xtr.vangl2emNXR | X. tropicalis | vangl2 | CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... | NXR |
| Xtr.tspan8em3Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at... | NXR |
| Xla.trilemNXR | X. laevis | tril.L tril.S | CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Co-injected for both L and S. Ge... | NXR |
| Xla.thrbem3NXR | X. laevis | thrb.L | Double CRISPR mutant line of thrb (thyroid hormone receptor, beta ) with animals carrying a 8bp dele... | |
| Xla.thrbem2NXR | X. laevis | thrb.S | CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed... | |
| Xla.thrbem1NXR | X. laevis | thrb.L | CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). germline transmission confirmed... | |
| Xtr.tdrd1emNXR | X. tropicalis | tdrd1 | CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... | NXR |
| Xtr.srd5a3emNXR | X. tropicalis | srd5a3 | CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. F1 growin... |
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