Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.ripk4emNXR | X. tropicalis | ripk4 | CRISPR knockout targeting ripk4 (receptor interacting serine/threonine kinase 4). Germline transmiss... | NXR |
| Xtr.amhr2em2NXR | X. tropicalis | amhr2 | CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Germ line transmission not yet ... | NXR |
| Xtr.vwa2emNXR | X. tropicalis | vwa2 | CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... | NXR |
| Xla.ar em1NXR | X. laevis | ar.L | CRISPR mutation of ar (androgen receptor). Animals carry a 13 base pair deletion in ar.L Germline tr... | NXR |
| Xla.dmrt1em3NXR | X. laevis | dmrt1.S | CRISPR knockout of dmrt1.S (doublesex and mab-3 related transcription factor 1 ). Custom mutant line... | NXR |
| Xla.Tg(WntREs:dEGFP)Vlemx | X. laevis | Construct contains a synthetic Wnt-responsive promoter consisting of 7 copies of a TCF/LEF1 binding... | ||
| Xtr.vangl2emNXR | X. tropicalis | vangl2 | CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2). Germ line transmission not yet con... | NXR |
| Xtr.mtnr1aemNXR | X. tropicalis | mtnr1a | CRISPR knock out of mtnr1a (melatonin receptor 1A ). Germ line transmission confirmed. Animals carry... | NXR |
| Xtr.fibinemHorb | X. tropicalis | fibin | CRISPR knockout of fibin (fin bud initiation factor homolog), Confirmed germline transmission. Custo... | NXR |
| Xtr.zbtb21em2Horb | X. tropicalis | zbtb14 | CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Different sgRNA sequence from ... | NXR |
| Xla.mcidasemHorb | X. laevis | mcidas.L | CRISPR knockout of mcidas (multiciliate differentiation and DNA synthesis associated cell cycle prot... | |
| Xla.Tg(rho:hsa.rhosub_P23H) | X. laevis | Line with a human mutant form of rhodopsin with a Proline to Histidine substitution, which leads to ... | ||
| Xla.runx1em(GFP)EXRC | X. laevis | runx1.L | CRISPR-Cas9 mediated insertion of IRES-GFP sequence into the 3'-UTR of runx1 gene, | |
| Xtr.xbp1emNXR | X. tropicalis | xbp1 | CRISPR KO of xbp1 (X-box binding protein 1). Germ line transmission has been confirmed. Animals carr... | NXR |
| Xla.cxcl8b.2em2Horb | X. laevis | cxcl8b.2.L | CRISPR knockout of cxcl8b (C-X-C motif chemokine ligand 8) and also known as il8b (interleukin-8). G... | NXR |
| Xtr.hpse2emHorb | X. tropicalis | hpse2 | CRISPR knockout of hpse2 (heparanase 2 (inactive)). Confirmed germline transmission. Custom mutant g... | NXR |
| Xla.Tg(CMV:GFP,dsRED)Amaya | X. laevis | The constitutive simian cytomegalovirus (CMV) IE94 promoter/enhancer driving GFP flanked by FRT site... | ||
| Xtr.erfemHorb | X. tropicalis | erf | CRISPR knockout of erf (ETS2 repressor factor). Germline transmission not yet confirmed. Custom muta... | NXR |
| Xtr.Tg(otx2:Gal4)Zimml | X. tropicalis | Otx2 promoter driving Gal4 expression. | ||
| Xtr.ripply3emNXR | X. tropicalis | ripply3 | CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ line transmission confirmed. Animal... | NXR |
| Xla.velo1emNXR | X. laevis | velo1.L | X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized. Germ line... | NXR |
| Xtr.sobpemNXR | X. tropicalis | sobp | CRISPR knockout of sobp (sine oculis binding protein homolog). Germline transmission confirmed. Anim... | NXR |
| Xla.Tg(CMV:hist2h2be-RFP;cryga:VenusNXR | X. laevis | CMV promoterdriving Xenopus Histone 2B (xH2B, or hist2h2b)- RFP. fusion, with crystallin gamma A dri... | ||
| Xla.Tg(Xtr.hal2:eGFP;cryga:GFP3)Shi | X. laevis | This tg line carries a 4.4-kb HAL2 promoter in AcGFP1.1 vexctor , subcloned into the KpnI-AgeI diges... | ||
| Xla.Tg(Mmu.tal1:GFP)Patnt | X. laevis | Mouse SCL +19 enhancer which contains a GATA-ETS-GATA core motif driving GFP | ||
| Xtr.Et(CAGGS-SB10;cryga:RFP;CAGGS:GFP)6MMead | X. tropicalis | NXR | ||
| Xtr.clec4eemHorb | X. tropicalis | clec4e | CRISPR knockout of clec4e (C-type lectin domain family 4 member E). Germline transmission not yet co... | NXR |
| Xla.myf6emNXR | X. laevis | myf6.L | TALENS knockout of myf6 (myogenic factor 6) in X. laevis. Germ line transmission confirmed. Contact... | NXR |
| Xtr.Tg(tubb2b:GFP)Amaya | X. tropicalis | Xenopus n-tubulin (tubb2b) promoter driving GFP. | NXR | |
| Xtr.cbsemNXR | X. tropicalis | cbs | CRISPR knockout targeting cbs (cystathionine-beta-synthase). Germ line transmission not yet confirme... | NXR |
| Xla.myf5emNXR | X. laevis | myf5.L | CRISPR knockout of myf5 (myogenic factor 5). Germ line transmission not yet confirmed. F0 founders. ... | NXR |
| Xla.Tg(CMV:Aequorin,GFP)NXR | X. laevis | CMV promoter driving expression of Aequorin and GFP. Aequorin is a Ca2+-dependent bioluminescence ph... | ||
| Xla.WCM3xNF1NXR | X. laevis | |||
| Xtr. IvoryCoast1EXRC | X. tropicalis | Ivory Coast X. tropicalis established from the colony at MRC/Mill Hill. Outbred for 15+ generations. | ||
| Xtr.zmym4emNXR | X. tropicalis | zmym4 | CRISPR KO of zmym4 (zinc finger MYM-type containing 4). Germline transmission confirmed. Animals car... | NXR |
| Xtr.rfx6emNXR | X. tropicalis | rfx6 | CRISPR KO of rfx6 (regulatory factor X6) in X. tropicalis. Germ line transmission confirmed. Anim... | NXR |
| Xtr.runx1t1emHorb | X. tropicalis | runx1t1 | CRISPR knockout of runx1t1(RUNX1 partner transcriptional co-repressor 1) gene. Germ line transmissio... | NXR |
| Xtr.bmpr1aemHorb | X. tropicalis | bmpr1a | CRISPR knockout targeting bmpr1a (bone morphogenetic protein receptor type 1A) enhancer region. Cust... | NXR |
| Xla.Tg(slurp1l:GFP)Mohun | X. laevis | 5 kb of promoter of the X. laevis slurp1l (aka LURP-1) gene driving expression of GFP | ||
| Xtr.Tg(UAS:mapt-Venus:Hsa.UBC:Gal4-VP16)Amaya | X. tropicalis | UAS driving mapt-Venus fusion expresssion to label mictrotubules. Ubiquitous Gal4-VP16 fusion expres... | ||
| Xla.Tg(Rno.elas:rtTA;TRE:notchIC;cryga:GFP)Brown | X. laevis | Tetracycline inducible activated Notch expression in the exocrine pancreas. | ||
| Xla.dmrt1em4NXR | X. laevis | dmrt1.L dmrt1.S | Double X. laevis CRISPR knockout line, targeting both dmrt1.S and dmrt1.L (doublesex and mab-3 relat... | NXR |
| Xla.wtTEFOR | X. laevis | Wild-type Xenopus laevis from TEFOR Paris-Saclay | ||
| Xtr.shroom3emHorb | X. tropicalis | shroom3 | CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... | NXR |
| Xtr.prph2em2Horb | X. tropicalis | prph2 | CRISPR knockout of prph2 (peripherin 2). Confirmed germ line transmission. Animals carry a 4 base pa... | NXR |
| Xla.Oxford | X. laevis | |||
| Xla.Tg(CMV:memGFP;cryga:mCherry)NXR | X. laevis | CMV promoter driving expression of membrane bound GFP, and a gamma-crystallin (cryga) driving expres... | ||
| Xla.Tg(myl2:eGFP)Mohun | X. laevis | ~3kb myosin light chain (myl2, also known as xmlc2/mlc2) promoter driving enhanced GFP (eGFP) expres... | ||
| Xtr.snai2emNXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | NXR |
| Xtr.eya1emNXR | X. tropicalis | eya1 | CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... |
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