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Results 1 - 50 of 214 results

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Line Name Species Mutated Gene Description Availability
Xtr.fermt2tm-/- Huzha X. tropicalis fermt2 This is a CRISPR generated mutant giving rise to a 10bp deletion in the fermt2/kindlin2 gene.
Xtr.apcMRCΔ1/+Vlemx X. tropicalis apc F0 apc mosaics generated by apc TALENs injection, were outcrossed with WT X. tropicalis, and offspri...
Xtr.Tg(mlc2:dnfosl1-eGFP)Qi X. tropicalis fosl1 Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc...
Xtr.mtnr1aemNXR X. tropicalis mtnr1a CRISPR knock out of mtnr1a (melatonin receptor 1A ) in X. tropicalis. germ line transmission confirm... NXR
Xtr.six1em2NXR X. tropicalis six1 CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc...
Xtr.zmym4emNXR X. tropicalis zmym4 CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi...
Xtr.zeb2emNXR X. tropicalis zeb2 CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro...
Xtr.ywhazemNXR X. tropicalis ywhaz CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge...
Xtr.xbp1emNXR X. tropicalis xbp1 CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma...
Xla.baz1bemNXR X. laevis baz1b.L TALENs knockout of baz1b (bromodomain adjacent to zinc finger domain 1B ) aka wstf,a gene associated...
Xla.wnt11bemNXR X. laevis wnt11b.L CRISPR knockout of wnt11b in X laevis. Germline transmission confirmed. F2 animals carry a 13bp del...
Xtr.wnt11bemNXR X. tropicalis wnt11b CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran...
Xtr.wbp11emNXR X. tropicalis wbp11 CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin...
Xtr.vwa2emNXR X. tropicalis vwa2 CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf...
Xtr.vangl2emNXR X. tropicalis vangl2 CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub...
Xtr.tspan8em3Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at...
Xtr.tspan8em2Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at...
Xla.trilemNXR X. laevis tril.L CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Germ line transmission not yet c...
Xla.thrbem3NXR X. laevis thrb.L Double CRISPR mutant line of thrb (thyroid hormone receptor, beta ) with animals carrying a 8bp dele...
Xla.thrbem2NXR X. laevis thrb.S CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed...
Xla.thrbem1NXR X. laevis thrb.L CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). germline transmission confirmed...
Xtr.tdrd1emNXR X. tropicalis tdrd1 CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi...
Xtr.srd5a3emNXR X. tropicalis srd5a3 CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission not yet confirmed. C...
Xtr.srd5a2emNXR X. tropicalis srd5a2 CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c...
Xla.sobpemNXR X. tropicalis sobp CRISPR knockout of sobp (sine oculis binding protein homolog ), a gene associated with MRAMS, an in...
Xtr.snai2emNXR X. tropicalis snai2 CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi...
Xtr.snai1emNXR X. tropicalis snai1 CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir...
Xtr.six1em1NXR X. tropicalis six1 CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc...
Xtr.sf3b4emNXR X. tropicalis sf3b4 CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ...
Xla.slc45a2em2NXR X. laevis slc45a2.L CRISPR knockout of slc45a2 (solute carrier family 45 member 2 ). Screened for germline transmission....
Xla.slc45a2emNXR X. laevis slc45a2.L
Xtr.foxn1tmHuarc X. tropicalis foxn1 Athymic line with TALEN-mediated targeted mutation in foxn1 gene. Absence of immunological rejection...
Xtr.rxraemNXR X. tropicalis rxra CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Contact NXR...
Xtr.runx1em3NXR X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...
Xtr.runx1em2NXR X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...
Xtr.rspo2emNXR X. tropicalis rspo2 CRISPR knockout of rspo2 (R-spondin 2 ). Germ line transmission confirmed. Contact NXR for more deta...
Xtr.ror2emNXR X. tropicalis ror2 CRISPR knockout of ror2 (receptor tyrosine kinase like orphan receptor 2). Germ line transmission no...
Xtr.ripply3emNXR X. tropicalis ripply3 CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ line transmission not yet confirmed....
Xtr.rfx6emNXR X. tropicalis rfx6 CRISPR KO of rfx6 (regulatory factor X6) in X. tropicalis. Germ line transmission not yet confirm...
Xtr.rflciiemNXR X. tropicalis rflcii CRISPR KO of rflcii ( relaxin family locus C type II ) in X tropicalis. Germ line transmission not y...
Xla.prkdcemNXR X. laevis prkdc.L CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission not y...
Xtr.pqbp1emNXR X. tropicalis pqbp1 CRISPR KO of pqbp1 (polyglutamine binding protein 1) in X tropicalis. Germ line transmission confirm...
Xtr.pou4f1emNXR X. tropicalis pou4f1 CRISPR knockout of pou4f1 (POU class 4 homeobox 1) in X. tropicalis. germ line transmission confirme...
Xtr.pnhdemNXR X. tropicalis pnhd CRISPR knockout of pnhd (pinhead) in X tropicalis. germ line transmission confirmed. Mutation is a ...
Xtr.plekhg5emNXR X. tropicalis plekhg5 CRISPR knockout of plekhg5 (pleckstrin homology and RhoGEF domain containing G5 ) Germ line transmis...
Xtr.pigpemNXR X. tropicalis pigp CRISPR knockout of pigp (phosphatidylinositol glycan anchor biosynthesis class P )in X tropicalis. G...
Xtr.olig3emNXR X. tropicalis olig3 CRISPR knockout of olig3 (oligodendrocyte transcription factor 3) in X. tropicalis. Current mosaic ...
Xtr.nr2f2emNXR X. tropicalis nr2f2 CRISPR knockout fo nr2f2 (nuclear receptor subfamily 2 group F member 2 ). Germ line transmission co...
Xtr.naa20emNXR X. tropicalis naa20 CRISPR knockout fo naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit ). Germ line transmi...
Xla.myod1em2NXR X. laevis myod1.L CRISPR knockout of myod1 (myogenic differentiation 1) in X laevis. Germ line transmission not yet co...

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