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Summary Expression Phenotypes Gene Literature (308) GO Terms (6) Nucleotides (92) Proteins (53) Interactants (177) Wiki
XB--1004370

Papers associated with kcnj3



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Hydrogen-bonding dynamics between adjacent blades in G-protein beta-subunit regulates GIRK channel activation., Mirshahi T, Logothetis DE, Rosenhouse-Dantsker A., Biophys J. April 15, 2006; 90 (8): 2776-85.

Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil., Kobayashi T, Washiyama K, Ikeda K., Neuropsychopharmacology. March 1, 2006; 31 (3): 516-24.

G protein-activated inwardly rectifying K+ channel inhibition and rescue of weaver mouse motor functions by antidepressants., Takahashi T, Kobayashi T, Ozaki M, Takamatsu Y, Ogai Y, Ohta M, Yamamoto H, Ikeda K., Neurosci Res. February 1, 2006; 54 (2): 104-11.

Tyrosine phosphorylation of K(ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress., Ippolito DL, Xu M, Bruchas MR, Wickman K, Chavkin C., J Biol Chem. December 16, 2005; 280 (50): 41683-93.

Differential ion current activation by human 5-HT(1A) receptors in Xenopus oocytes: evidence for agonist-directed trafficking of receptor signalling., Heusler P, Pauwels PJ, Wurch T, Newman-Tancredi A, Tytgat J, Colpaert FC, Cussac D., Neuropharmacology. December 1, 2005; 49 (7): 963-76.

A difference in inward rectification and polyamine block and permeation between the Kir2.1 and Kir3.1/Kir3.4 K+ channels., Makary SM, Claydon TW, Enkvetchakul D, Nichols CG, Boyett MR., J Physiol. November 1, 2005; 568 (Pt 3): 749-66.

Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner., Kanjhan R, Coulson EJ, Adams DJ, Bellingham MC., J Pharmacol Exp Ther. September 1, 2005; 314 (3): 1353-61.

Evidence for sequential ion-binding loci along the inner pore of the IRK1 inward-rectifier K+ channel., Shin HG, Xu Y, Xu Y, Lu Z., J Gen Physiol. August 1, 2005; 126 (2): 123-35.                            

Phosphorylation of a tyrosine at the N-terminus regulates the surface expression of GIRK5 homomultimers., Mora SI, Escobar LI., FEBS Lett. June 6, 2005; 579 (14): 3019-23.

Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels., Rishal I, Porozov Y, Yakubovich D, Varon D, Dascal N., J Biol Chem. April 29, 2005; 280 (17): 16685-94.

Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification., Pegan S, Arrabit C, Zhou W, Kwiatkowski W, Collins A, Slesinger PA, Choe S., Nat Neurosci. March 1, 2005; 8 (3): 279-87.

Mutation of critical GIRK subunit residues disrupts N- and C-termini association and channel function., Sarac R, Hou P, Hurley KM, Hriciste D, Cohen NA, Nelson DJ., J Neurosci. February 16, 2005; 25 (7): 1836-46.

Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex., Clancy SM, Fowler CE, Finley M, Suen KF, Arrabit C, Berton F, Kosaza T, Casey PJ, Slesinger PA., Mol Cell Neurosci. February 1, 2005; 28 (2): 375-89.

Molecular cloning and characterization of a new RGS protein of Medaka., Itoh M, Nagatomo K, Kubo Y, Sugimoto M, Saitoh O., Gene. January 31, 2005; 345 (2): 165-71.

RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat., Pertovaara A, Ostergård M, Ankö ML, Lehti-Koivunen S, Brandt A, Hong W, Korpi ER, Panula P., Neuroscience. January 1, 2005; 134 (3): 1023-32.

Kinetic modeling of Na(+)-induced, Gbetagamma-dependent activation of G protein-gated K(+) channels., Yakubovich D, Rishal I, Dascal N., J Mol Neurosci. January 1, 2005; 25 (1): 7-19.

Effects of interferon-alpha on cloned opioid receptors expressed in Xenopus oocytes., Kobayashi T, Washiyama K, Ikeda K., Life Sci. December 10, 2004; 76 (4): 407-15.

Carboxy-terminal determinants of conductance in inward-rectifier K channels., Zhang YY, Robertson JL, Gray DA, Palmer LG., J Gen Physiol. December 1, 2004; 124 (6): 729-39.                      

Modulators of G protein-activated inwardly rectifying K+ channels: potentially therapeutic agents for addictive drug users., Kobayashi T, Washiyama K, Ikeda K., Ann N Y Acad Sci. October 1, 2004; 1025 590-4.

K+ activation of kir3.1/kir3.4 and kv1.4 K+ channels is regulated by extracellular charges., Claydon TW, Makary SY, Dibb KM, Boyett MR., Biophys J. October 1, 2004; 87 (4): 2407-18.

Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs., Kobayashi T, Washiyama K, Ikeda K., Neuropsychopharmacology. October 1, 2004; 29 (10): 1841-51.

Short variable sequence acquired in evolution enables selective inhibition of various inward-rectifier K+ channels., Ramu Y, Klem AM, Lu Z., Biochemistry. August 24, 2004; 43 (33): 10701-9.

The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus., Milovic S, Steinecker-Frohnwieser B, Schreibmayer W, Weigl LG., J Biol Chem. August 13, 2004; 279 (33): 34240-9.

Gbetagamma-activated inwardly rectifying K(+) (GIRK) channel activation kinetics via Galphai and Galphao-coupled receptors are determined by Galpha-specific interdomain interactions that affect GDP release rates., Zhang Q, Dickson A, Doupnik CA., J Biol Chem. July 9, 2004; 279 (28): 29787-96.

A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade., Dhingra A, Faurobert E, Dascal N, Sterling P, Vardi N., J Neurosci. June 23, 2004; 24 (25): 5684-93.

G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes., Itzhaki Van-Ham I, Peleg S, Dascal N, Shapira H, Oron Y., FEBS Lett. April 23, 2004; 564 (1-2): 157-60.

Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel., Ivanina T, Varon D, Peleg S, Rishal I, Porozov Y, Dessauer CW, Keren-Raifman T, Dascal N., J Biol Chem. April 23, 2004; 279 (17): 17260-8.

Molecular determinants responsible for differential cellular distribution of G protein-gated inwardly rectifying K+ channels., Mirshahi T, Logothetis DE., J Biol Chem. March 19, 2004; 279 (12): 11890-7.

betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation., Finley M, Arrabit C, Fowler C, Suen KF, Slesinger PA., J Physiol. March 16, 2004; 555 (Pt 3): 643-57.

Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction., Zhang L, Lee JK, Lee JK, John SA, Uozumi N, Kodama I., J Biol Chem. February 20, 2004; 279 (8): 7037-47.

Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C., Mao J, Wang X, Chen F, Wang R, Rojas A, Shi Y, Piao H, Jiang C., Proc Natl Acad Sci U S A. January 27, 2004; 101 (4): 1087-92.

Measuring the modulatory effects of RGS proteins on GIRK channels., Doupnik CA, Jaén C, Zhang Q., Methods Enzymol. January 1, 2004; 389 131-54.

The selectivity filter may act as the agonist-activated gate in the G protein-activated Kir3.1/Kir3.4 K+ channel., Claydon TW, Makary SY, Dibb KM, Boyett MR., J Biol Chem. December 12, 2003; 278 (50): 50654-63.

Critical determinants of the G protein gamma subunits in the Gbetagamma stimulation of G protein-activated inwardly rectifying potassium (GIRK) channel activity., Peng L, Mirshahi T, Zhang H, Hirsch JP, Logothetis DE., J Biol Chem. December 12, 2003; 278 (50): 50203-11.

Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel., Ivanina T, Rishal I, Varon D, Mullner C, Frohnwieser-Steinecke B, Schreibmayer W, Dessauer CW, Dascal N., J Biol Chem. August 1, 2003; 278 (31): 29174-83.

beta-Funaltrexamine, a gauge for the recognition site of wildtype and mutant H297Q mu-opioid receptors., Spivak CE, Beglan CL, Zöllner C, Surratt CK., Synapse. July 1, 2003; 49 (1): 55-60.

The M2 muscarinic G-protein-coupled receptor is voltage-sensitive., Ben-Chaim Y, Tour O, Dascal N, Parnas I, Parnas H., J Biol Chem. June 20, 2003; 278 (25): 22482-91.

RGS9 modulates dopamine signaling in the basal ganglia., Rahman Z, Schwarz J, Gold SJ, Zachariou V, Wein MN, Choi KH, Kovoor A, Chen CK, DiLeone RJ, Schwarz SC, Selley DE, Sim-Selley LJ, Barrot M, Luedtke RR, Self D, Neve RL, Lester HA, Simon MI, Nestler EJ., Neuron. June 19, 2003; 38 (6): 941-52.

Effects of ginsenoside on G protein-coupled inwardly rectifying K+ channel activity expressed in Xenopus oocytes., Choi S, Lee JH, Lee JH, Kim YI, Kang MJ, Rhim H, Lee SM, Nah SY., Eur J Pharmacol. May 9, 2003; 468 (2): 83-92.

Conformational rearrangements associated with the gating of the G protein-coupled potassium channel revealed by FRET microscopy., Riven I, Kalmanzon E, Segev L, Reuveny E., Neuron. April 24, 2003; 38 (2): 225-35.

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids., Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ., J Biol Chem. March 28, 2003; 278 (13): 11312-9.

Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac)., Kobayashi T, Washiyama K, Ikeda K., Br J Pharmacol. March 1, 2003; 138 (6): 1119-28.

Effects of extracellular sodium on mu-opioid receptors coupled to potassium channels coexpressed in Xenopus oocytes., Oz M, Spivak CE., Pflugers Arch. March 1, 2003; 445 (6): 716-20.

Serine 329 of the mu-opioid receptor interacts differently with agonists., Pil J, Tytgat J., J Pharmacol Exp Ther. March 1, 2003; 304 (3): 924-30.

Inhibition of G-protein-coupled inward rectifying K+ channels by intracellular acidosis., Mao J, Wu J, Chen F, Wang X, Jiang C., J Biol Chem. February 28, 2003; 278 (9): 7091-8.

Na+ promotes the dissociation between Galpha GDP and Gbeta gamma, activating G protein-gated K+ channels., Rishal I, Keren-Raifman T, Yakubovich D, Ivanina T, Dessauer CW, Slepak VZ, Dascal N., J Biol Chem. February 7, 2003; 278 (6): 3840-5.

Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation., Müllner D., Biophys J. February 1, 2003; 84 (2 Pt 1): 1399-409.

Opioid receptor coupling to GIRK channels. In vitro studies using a Xenopus oocyte expression system and in vivo studies on weaver mutant mice., Ikeda K, Yoshii M, Sora I, Kobayashi T., Methods Mol Med. January 1, 2003; 84 53-64.

A role for the middle C terminus of G-protein-activated inward rectifier potassium channels in regulating gating., Guo Y, Waldron GJ, Murrell-Lagnado R., J Biol Chem. December 13, 2002; 277 (50): 48289-94.

Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation., Zhang Q, Pacheco MA, Doupnik CA., J Physiol. December 1, 2002; 545 (2): 355-73.

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