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Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. , Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R ., J Bone Miner Res. November 1, 2006; 21 (11): 1738-49.
The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition. , Cruciat CM, Hassler C, Niehrs C ., J Biol Chem. May 5, 2006; 281 (18): 12986-93.
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. , Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R , Okamura H, Woodgett J, He X ., Nature. December 8, 2005; 438 (7069): 873-7.
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. , Davidson G, Wu W, Shen J, Bilic J, Fenger U, Stannek P, Glinka A , Niehrs C ., Nature. December 8, 2005; 438 (7069): 867-72.
Early steps in neural crest specification. , Barembaum M, Bronner-Fraser M ., Semin Cell Dev Biol. December 1, 2005; 16 (6): 642-6.
Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling. , Swain RK, Katoh M, Medina A, Steinbeisser H ., Cell Commun Signal. October 19, 2005; 3 12.
SOST is a ligand for LRP5/ LRP6 and a Wnt signaling inhibitor. , Semënov M, Tamai K, He X ., J Biol Chem. July 22, 2005; 280 (29): 26770-5.
Comparative genomics on Dkk1 orthologs. , Katoh Y, Katoh M., Int J Oncol. July 1, 2005; 27 (1): 275-9.
Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. , Yamamoto A, Nagano T, Takehara S, Hibi M, Aizawa S ., Cell. January 28, 2005; 120 (2): 223-35.
Connective- tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex. , Mercurio S, Latinkic B , Itasaki N, Krumlauf R , Smith JC ., Development. May 1, 2004; 131 (9): 2137-47.
Wise, a context-dependent activator and inhibitor of Wnt signalling. , Itasaki N, Jones CM , Mercurio S, Rowe A, Domingos PM , Smith JC , Krumlauf R ., Development. September 1, 2003; 130 (18): 4295-305.
Kremen2 modulates Dickkopf2 activity during Wnt/ LRP6 signaling. , Mao B , Niehrs C ., Gene. January 2, 2003; 302 (1-2): 179-83.
Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. , Davidson G, Mao B , del Barco Barrantes I, Niehrs C ., Development. December 1, 2002; 129 (24): 5587-96.
A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling. , Holmen SL, Salic A, Zylstra CR, Kirschner MW , Williams BO., J Biol Chem. September 20, 2002; 277 (38): 34727-35.
Cloning and expression of Xenopus Lrp5 and Lrp6 genes. , Houston DW , Wylie C ., Mech Dev. September 1, 2002; 117 (1-2): 337-42.
Regulation of Wnt/ LRP signaling by distinct domains of Dickkopf proteins. , Brott BK, Sokol SY ., Mol Cell Biol. September 1, 2002; 22 (17): 6100-10.
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. , Semënov MV, Tamai K, Brott BK, Kühl M , Sokol S , He X ., Curr Biol. June 26, 2001; 11 (12): 951-61.
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. , Mao B , Wu W, Li Y, Hoppe D, Stannek P, Glinka A , Niehrs C ., Nature. May 17, 2001; 411 (6835): 321-5.
LDL-receptor-related proteins in Wnt signal transduction. , Tamai K, Semenov M, Kato Y , Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP , He X ., Nature. September 28, 2000; 407 (6803): 530-5.