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Summary Expression Phenotypes Gene Literature (242) GO Terms (8) Nucleotides (225) Proteins (62) Interactants (1337) Wiki
XB--482929

Papers associated with smad2



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TGF-beta signaling is required for multiple processes during Xenopus tail regeneration., Ho DM, Whitman M., Dev Biol. March 1, 2008; 315 (1): 203-16.                  

Coordination of cell polarity during Xenopus gastrulation., Shindo A, Yamamoto TS, Ueno N., PLoS One. February 6, 2008; 3 (2): e1600.              

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm., Spagnoli FM, Brivanlou AH., Development. February 1, 2008; 135 (3): 451-61.                                                    

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice., Pangas SA, Li X, Umans L, Zwijsen A, Huylebroeck D, Gutierrez C, Wang D, Martin JF, Jamin SP, Behringer RR, Robertson EJ, Matzuk MM., Mol Cell Biol. January 1, 2008; 28 (1): 248-57.

Unexpected activities of Smad7 in Xenopus mesodermal and neural induction., de Almeida I, Rolo A, Batut J, Hill C, Stern CD, Linker C., Mech Dev. January 1, 2008; 125 (5-6): 421-31.              

Long-range action of Nodal requires interaction with GDF1., Tanaka C, Sakuma R, Nakamura T, Hamada H, Saijoh Y., Genes Dev. December 15, 2007; 21 (24): 3272-82.        

Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction., Pinho S, Niehrs C., Differentiation. December 1, 2007; 75 (10): 957-67.            

Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus., Saka Y, Hagemann AI, Piepenburg O, Smith JC., Development. December 1, 2007; 134 (23): 4209-18.

Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation., Chang C, Harland RM., Development. November 1, 2007; 134 (21): 3861-72.                

Regulation of the Xenopus Xsox17alpha(1) promoter by co-operating VegT and Sox17 sites., Howard L, Rex M, Clements D, Woodland HR., Dev Biol. October 15, 2007; 310 (2): 402-15.      

Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation., Morris SA, Almeida AD, Tanaka H, Ohta K, Ohnuma S., PLoS One. October 10, 2007; 2 (10): e1004.                    

XSUMO-1 is required for normal mesoderm induction and axis elongation during early Xenopus development., Yukita A, Michiue T, Danno H, Asashima M., Dev Dyn. October 1, 2007; 236 (10): 2757-66.    

Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain., Dai F, Chang C, Lin X, Dai P, Mei L, Feng XH., Mol Cell Biol. September 1, 2007; 27 (17): 6183-94.

Interpretation of BMP signaling in early Xenopus development., Simeoni I, Gurdon JB., Dev Biol. August 1, 2007; 308 (1): 82-92.                  

The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning., Sander V, Reversade B, De Robertis EM., EMBO J. June 20, 2007; 26 (12): 2955-65.              

The secreted EGF-Discoidin factor xDel1 is essential for dorsal development of the Xenopus embryo., Arakawa A, Matsuo-Takasaki M, Takai A, Inomata H, Matsumura M, Ikeya M, Takahashi K, Miyachi Y, Sasai N, Sasai Y., Dev Biol. June 1, 2007; 306 (1): 160-9.                    

Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei., Koziol MJ, Garrett N, Gurdon JB., Curr Biol. May 1, 2007; 17 (9): 801-7.        

Endofin acts as a Smad anchor for receptor activation in BMP signaling., Shi W, Chang C, Nie S, Xie S, Wan M, Cao X., J Cell Sci. April 1, 2007; 120 (Pt 7): 1216-24.

Negative regulation of Activin/Nodal signaling by SRF during Xenopus gastrulation., Yun CH, Choi SC, Park E, Kim SJ, Chung AS, Lee HK, Lee HK, Lee HJ, Lee HJ, Han JK., Development. February 1, 2007; 134 (4): 769-77.              

Kinesin-mediated transport of Smad2 is required for signaling in response to TGF-beta ligands., Batut J, Howell M, Hill CS., Dev Cell. February 1, 2007; 12 (2): 261-74.  

Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways., Sapkota G, Knockaert M, Alarcón C, Montalvo E, Brivanlou AH, Massagué J., J Biol Chem. December 29, 2006; 281 (52): 40412-9.

Xenopus Dab2 is required for embryonic angiogenesis., Cheong SM, Choi SC, Han JK., BMC Dev Biol. December 19, 2006; 6 63.                  

FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development., Steiner AB, Engleka MJ, Lu Q, Piwarzyk EC, Yaklichkin S, Lefebvre JL, Walters JW, Pineda-Salgado L, Labosky PA, Kessler DS., Development. December 1, 2006; 133 (24): 4827-38.                    

Dullard promotes degradation and dephosphorylation of BMP receptors and is required for neural induction., Satow R, Kurisaki A, Chan TC, Hamazaki TS, Asashima M., Dev Cell. December 1, 2006; 11 (6): 763-74.              

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling., Knockaert M, Sapkota G, Alarcón C, Massagué J, Brivanlou AH., Proc Natl Acad Sci U S A. August 8, 2006; 103 (32): 11940-5.

Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo., Ho DM, Chan J, Bayliss P, Whitman M., Dev Biol. July 15, 2006; 295 (2): 730-42.            

A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos., Dorey K, Hill CS., Dev Biol. April 15, 2006; 292 (2): 303-16.  

Genomic profiling of mixer and Sox17beta targets during Xenopus endoderm development., Dickinson K, Leonard J, Baker JC., Dev Dyn. February 1, 2006; 235 (2): 368-81.                        

GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos., Levine AJ, Brivanlou AH., Development. January 1, 2006; 133 (2): 209-16.            

Determination of the minimal domains of Mix.3/Mixer required for endoderm development., Doherty JR, Zhu H, Kuliyev E, Mead PE., Mech Dev. January 1, 2006; 123 (1): 56-66.                  

Vg 1 is an essential signaling molecule in Xenopus development., Birsoy B, Kofron M, Schaible K, Wylie C, Heasman J., Development. January 1, 2006; 133 (1): 15-20.    

Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads., Schmierer B, Hill CS., Mol Cell Biol. November 1, 2005; 25 (22): 9845-58.

The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo., Collart C, Verschueren K, Rana A, Smith JC, Huylebroeck D., Development. October 1, 2005; 132 (20): 4575-86.        

BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos., Gamer LW, Nove J, Levin M, Rosen V., Dev Biol. September 1, 2005; 285 (1): 156-68.              

Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors., Ku M, Sokol SY, Wu J, Tussie-Luna MI, Roy AL, Hata A., Mol Cell Biol. August 1, 2005; 25 (16): 7144-57.

Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1., Alliston T, Ko TC, Cao Y, Liang YY, Feng XH, Chang C, Derynck R., J Biol Chem. June 24, 2005; 280 (25): 24227-37.

Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A., Abe T, Furue M, Kondow A, Matsuzaki K, Asashima M., Mech Dev. May 1, 2005; 122 (5): 671-80.            

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase., Dupont S, Zacchigna L, Cordenonsi M, Soligo S, Adorno M, Rugge M, Piccolo S., Cell. April 8, 2005; 121 (1): 87-99.                                  

Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1., Messenger NJ, Kabitschke C, Andrews R, Grimmer D, Núñez Miguel R, Blundell TL, Smith JC, Wardle FC., Dev Cell. April 1, 2005; 8 (4): 599-610.  

The ARID domain protein dril1 is necessary for TGF(beta) signaling in Xenopus embryos., Callery EM, Smith JC, Thomsen GH., Dev Biol. February 15, 2005; 278 (2): 542-59.                              

XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development., Birsoy B, Berg L, Williams PH, Smith JC, Wylie CC, Christian JL, Heasman J., Development. February 1, 2005; 132 (3): 591-602.                      

Conditional BMP inhibition in Xenopus reveals stage-specific roles for BMPs in neural and neural crest induction., Wawersik S, Evola C, Whitman M., Dev Biol. January 15, 2005; 277 (2): 425-42.                    

Visualizing long-range movement of the morphogen Xnr2 in the Xenopus embryo., Williams PH, Hagemann A, González-Gaitán M, Smith JC., Curr Biol. November 9, 2004; 14 (21): 1916-23.      

Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation., Daniels M, Shimizu K, Zorn AM, Ohnuma S., Development. November 1, 2004; 131 (22): 5613-26.                                

New roles for FoxH1 in patterning the early embryo., Kofron M, Puck H, Standley H, Wylie C, Old R, Whitman M, Heasman J., Development. October 1, 2004; 131 (20): 5065-78.              

Generation of novel conditional and hypomorphic alleles of the Smad2 gene., Liu Y, Festing MH, Hester M, Thompson JC, Weinstein M., Genesis. October 1, 2004; 40 (2): 118-123.  

Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling., Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K., J Biol Chem. July 23, 2004; 279 (30): 31568-74.

Smad2 and Smad3 coordinately regulate craniofacial and endodermal development., Liu Y, Festing M, Thompson JC, Hester M, Rankin S, Rankin S, El-Hodiri HM, Zorn AM, Weinstein M., Dev Biol. June 15, 2004; 270 (2): 411-26.  

Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells., De Bosscher K, Hill CS, Nicolás FJ., Biochem J. April 1, 2004; 379 (Pt 1): 209-16.

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