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Summary Expression Phenotypes Gene Literature (132) GO Terms (1) Nucleotides (120) Proteins (61) Interactants (71) Wiki
XB--977698

Papers associated with asic1



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A gating mutation in the internal pore of ASIC1a., Pfister Y, Gautschi I, Takeda AN, van Bemmelen M, Kellenberger S, Schild L., J Biol Chem. April 28, 2006; 281 (17): 11787-91.

Interaction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependent., Chen X, Kalbacher H, Gründer S., J Gen Physiol. March 1, 2006; 127 (3): 267-76.                      

Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism., Zhang P, Sigworth FJ, Canessa CM., J Gen Physiol. February 1, 2006; 127 (2): 109-17.              

The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a., Salinas M, Rash LD, Baron A, Lambeau G, Escoubas P, Lazdunski M., J Physiol. January 15, 2006; 570 (Pt 2): 339-54.

Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating., Vukicevic M, Weder G, Boillat A, Boesch A, Kellenberger S., J Biol Chem. January 13, 2006; 281 (2): 714-22.

Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli., Mogil JS, Breese NM, Witty MF, Ritchie J, Rainville ML, Ase A, Abbadi N, Stucky CL, Séguéla P., J Neurosci. October 26, 2005; 25 (43): 9893-901.

The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinity., Chen X, Kalbacher H, Gründer S., J Gen Physiol. July 1, 2005; 126 (1): 71-9.                  

The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation., Bianchi L, Gerstbrein B, Frøkjaer-Jensen C, Royal DC, Mukherjee G, Royal MA, Xue J, Schafer WR, Driscoll M., Nat Neurosci. December 1, 2004; 7 (12): 1337-44.

Identification of the Ca2+ blocking site of acid-sensing ion channel (ASIC) 1: implications for channel gating., Paukert M, Babini E, Pusch M, Gründer S., J Gen Physiol. October 1, 2004; 124 (4): 383-94.              

Selective regulation of acid-sensing ion channel 1 by serine proteases., Poirot O, Vukicevic M, Boesch A, Kellenberger S., J Biol Chem. September 10, 2004; 279 (37): 38448-57.

Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing., Roza C, Puel JL, Kress M, Baron A, Diochot S, Lazdunski M, Waldmann R., J Physiol. July 15, 2004; 558 (Pt 2): 659-69.

A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons., Diochot S, Baron A, Rash LD, Deval E, Escoubas P, Scarzello S, Salinas M, Lazdunski M., EMBO J. April 7, 2004; 23 (7): 1516-25.

The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1., Coric T, Zhang P, Todorovic N, Canessa CM., J Biol Chem. November 14, 2003; 278 (46): 45240-7.

Protein kinase C isoform antagonism controls BNaC2 (ASIC1) function., Berdiev BK, Xia J, Jovov B, Markert JM, Mapstone TB, Gillespie GY, Fuller CM, Bubien JK, Benos DJ., J Biol Chem. November 29, 2002; 277 (48): 45734-40.

Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1)., Babini E, Paukert M, Geisler HS, Grunder S., J Biol Chem. November 1, 2002; 277 (44): 41597-603.

Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes., Zhang P, Canessa CM., J Gen Physiol. October 1, 2002; 120 (4): 553-66.                    

Up-regulation of acid-gated Na(+) channels (ASICs) by cystic fibrosis transmembrane conductance regulator co-expression in Xenopus oocytes., Ji HL, Jovov B, Fu J, Bishop LR, Mebane HC, Fuller CM, Stanton BA, Benos DJ., J Biol Chem. March 8, 2002; 277 (10): 8395-405.

Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system., Alvarez de la Rosa D, Zhang P, Shao D, White F, Canessa CM., Proc Natl Acad Sci U S A. February 19, 2002; 99 (4): 2326-31.

Selective modulation of heteromeric ASIC proton-gated channels by neuropeptide FF., Catarsi S, Babinski K, Séguéla P., Neuropharmacology. October 1, 2001; 41 (5): 592-600.

Zn2+ and H+ are coactivators of acid-sensing ion channels., Baron A, Schaefer L, Lingueglia E, Champigny G, Lazdunski M., J Biol Chem. September 21, 2001; 276 (38): 35361-7.

Cloning and functional expression of ASIC-beta2, a splice variant of ASIC-beta., Ugawa S, Ueda T, Takahashi E, Hirabayashi Y, Yoneda T, Komai S, Shimada S., Neuroreport. September 17, 2001; 12 (13): 2865-9.

Molecular and functional characterization of acid-sensing ion channel (ASIC) 1b., Bässler EL, Ngo-Anh TJ, Geisler HS, Ruppersberg JP, Gründer S., J Biol Chem. September 7, 2001; 276 (36): 33782-7.

Single-channel properties of recombinant acid-sensitive ion channels formed by the subunits ASIC2 and ASIC3 from dorsal root ganglion neurons expressed in Xenopus oocytes., Zhang P, Canessa CM., J Gen Physiol. June 1, 2001; 117 (6): 563-72.                      

DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature., Askwith CC, Benson CJ, Welsh MJ, Snyder PM., Proc Natl Acad Sci U S A. May 22, 2001; 98 (11): 6459-63.

Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+., Babinski K, Catarsi S, Biagini G, Séguéla P., J Biol Chem. September 15, 2000; 275 (37): 28519-25.

Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels., Escoubas P, De Weille JR, Lecoq A, Diochot S, Waldmann R, Champigny G, Moinier D, Ménez A, Lazdunski M., J Biol Chem. August 18, 2000; 275 (33): 25116-21.

Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels., Askwith CC, Cheng C, Ikuma M, Benson C, Price MP, Welsh MJ., Neuron. April 1, 2000; 26 (1): 133-41.

On the molecular basis of ion permeation in the epithelial Na+ channel., Kellenberger S, Hoffmann-Pochon N, Gautschi I, Schneeberger E, Schild L., J Gen Physiol. July 1, 1999; 114 (1): 13-30.                  

Epithelial sodium channel regulatory proteins identified by functional expression cloning., Vallet V, Horisberger JD, Rossier BC., Kidney Int Suppl. September 1, 1998; 67 S109-14.

Mutations causing neurodegeneration in Caenorhabditis elegans drastically alter the pH sensitivity and inactivation of the mammalian H+-gated Na+ channel MDEG1., Champigny G, Voilley N, Waldmann R, Lazdunski M., J Biol Chem. June 19, 1998; 273 (25): 15418-22.

The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties., Bassilana F, Champigny G, Waldmann R, de Weille JR, Heurteaux C, Lazdunski M., J Biol Chem. November 14, 1997; 272 (46): 28819-22.

A proton-gated cation channel involved in acid-sensing., Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M., Nature. March 13, 1997; 386 (6621): 173-7.

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