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Summary Expression Phenotypes Gene Literature (361) GO Terms (12) Nucleotides (93) Proteins (38) Interactants (956) Wiki
XB--488110

Papers associated with tgfb1



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Determinants of specificity in TGF-beta signal transduction., Chen YG, Hata A, Lo RS, Wotton D, Shi Y, Pavletich N, Massagué J., Genes Dev. July 15, 1998; 12 (14): 2144-52.


Characterization of CMIX, a chicken homeobox gene related to the Xenopus gene mix.1., Peale FV, Sugden L, Bothwell M., Mech Dev. July 1, 1998; 75 (1-2): 167-70.


XTrR-I is a TGFbeta receptor and overexpression of truncated form of the receptor inhibits axis formation and dorsalising activity., Mahony D, Weis FM, Massagué J, Gurdon JB., Mech Dev. July 1, 1998; 75 (1-2): 95-105.


Characterization of human FAST-1, a TGF beta and activin signal transducer., Zhou S, Zawel L, Lengauer C, Kinzler KW, Vogelstein B., Mol Cell. July 1, 1998; 2 (1): 121-7.


Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2., Labbé E, Silvestri C, Hoodless PA, Wrana JL, Attisano L., Mol Cell. July 1, 1998; 2 (1): 109-20.


Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos., Joseph EM, Melton DA., Development. July 1, 1998; 125 (14): 2677-85.            


Smad6 functions as an intracellular antagonist of some TGF-beta family members during Xenopus embryogenesis., Nakayama T, Gardner H, Berg LK, Christian JL., Genes Cells. June 1, 1998; 3 (6): 387-94.                


The left-right coordinator: the role of Vg1 in organizing left-right axis formation., Hyatt BA, Yost HJ., Cell. April 3, 1998; 93 (1): 37-46.


Mads and Smads in TGF beta signalling., Attisano L, Wrana JL., Curr Opin Cell Biol. April 1, 1998; 10 (2): 188-94.


BMP1-related metalloproteinases promote the development of ventral mesoderm in early Xenopus embryos., Goodman SA, Albano R, Wardle FC, Matthews G, Tannahill D, Dale L., Dev Biol. March 15, 1998; 195 (2): 144-57.


Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells., Zhou S, Buckhaults P, Zawel L, Bunz F, Riggins G, Dai JL, Kern SE, Kinzler KW, Vogelstein B., Proc Natl Acad Sci U S A. March 3, 1998; 95 (5): 2412-6.


Role of TAK1 and TAB1 in BMP signaling in early Xenopus development., Shibuya H, Iwata H, Masuyama N, Gotoh Y, Yamaguchi K, Irie K, Matsumoto K, Nishida E, Ueno N., EMBO J. February 16, 1998; 17 (4): 1019-28.


Xenopus eHAND: a marker for the developing cardiovascular system of the embryo that is regulated by bone morphogenetic proteins., Sparrow DB, Kotecha S, Towers N, Mohun TJ., Mech Dev. February 1, 1998; 71 (1-2): 151-63.            


Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-beta upregulates their expression in cultured human skin cells., Sugiyama Y, Shimada A, Sayo T, Sakai S, Inoue S., J Invest Dermatol. February 1, 1998; 110 (2): 116-21.


XBMPRII, a novel Xenopus type II receptor mediating BMP signaling in embryonic tissues., Frisch A, Wright CV., Development. February 1, 1998; 125 (3): 431-42.                  


Maintenance of asymmetric nodal expression in Xenopus laevis., Lohr JL, Danos MC, Groth TW, Yost HJ., Dev Genet. January 1, 1998; 23 (3): 194-202.      


The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins., Latinkić BV, Umbhauer M, Neal KA, Lerchner W, Smith JC, Cunliffe V., Genes Dev. December 1, 1997; 11 (23): 3265-76.              


Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes., Liu F, Pouponnot C, Massagué J., Genes Dev. December 1, 1997; 11 (23): 3157-67.


The homeobox gene PV.1 mediates specification of the prospective neural ectoderm in Xenopus embryos., Ault KT, Xu RH, Kung HF, Jamrich M., Dev Biol. December 1, 1997; 192 (1): 162-71.            


Misexpression of chick Vg1 in the marginal zone induces primitive streak formation., Shah SB, Skromne I, Hume CR, Kessler DS, Lee KJ, Stern CD, Dodd J., Development. December 1, 1997; 124 (24): 5127-38.    


Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads., Candia AF, Watabe T, Hawley SH, Onichtchouk D, Zhang Y, Derynck R, Niehrs C, Cho KW., Development. November 1, 1997; 124 (22): 4467-80.


MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily., Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, He XY, Zhang HP, Donnellan M, Mahler S, Pryor K, Walsh BJ, Nicholson RC, Fairlie WD, Por SB, Robbins JM, Breit SN., Proc Natl Acad Sci U S A. October 14, 1997; 94 (21): 11514-9.


Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling., Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P., Nature. October 9, 1997; 389 (6651): 631-5.


A role for the roof plate and its resident TGFbeta-related proteins in neuronal patterning in the dorsal spinal cord., Liem KF, Tremml G, Jessell TM., Cell. October 3, 1997; 91 (1): 127-38.


The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds., Armes NA, Smith JC., Development. October 1, 1997; 124 (19): 3797-804.                


TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4., Nakao A, Imamura T, Souchelnytskyi S, Kawabata M, Ishisaki A, Oeda E, Tamaki K, Hanai J, Heldin CH, Miyazono K, ten Dijke P., EMBO J. September 1, 1997; 16 (17): 5353-62.


Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos., Meno C, Ito Y, Saijoh Y, Matsuda Y, Tashiro K, Kuhara S, Hamada H., Genes Cells. August 1, 1997; 2 (8): 513-24.    


Smad5 induces ventral fates in Xenopus embryo., Suzuki A, Chang C, Yingling JM, Wang XF, Hemmati-Brivanlou A., Dev Biol. April 15, 1997; 184 (2): 402-5.    


Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer., Joseph EM, Melton DA., Dev Biol. April 15, 1997; 184 (2): 367-72.        


Embryonic asymmetry: left TGFbeta at the right time?, King T, Brown NA., Curr Biol. April 1, 1997; 7 (4): R212-5.


Mesoderm induction by BMP-4 and -7 heterodimers., Suzuki A, Kaneko E, Maeda J, Ueno N., Biochem Biophys Res Commun. March 6, 1997; 232 (1): 153-6.


A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis., Chang C, Wilson PA, Mathews LS, Hemmati-Brivanlou A., Development. February 1, 1997; 124 (4): 827-37.                    


Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway., Nakao A, Röijer E, Imamura T, Souchelnytskyi S, Stenman G, Heldin CH, ten Dijke P., J Biol Chem. January 31, 1997; 272 (5): 2896-900.


Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3., Hansen CS, Marion CD, Steele K, George S, Smith WC., Development. January 1, 1997; 124 (2): 483-92.


Activin signalling has a necessary function in Xenopus early development., Dyson S, Gurdon JB., Curr Biol. January 1, 1997; 7 (1): 81-4.


Cancer gets Mad: DPC4 and other TGFbeta pathway genes in human cancer., Moskaluk CA, Kern SE., Biochim Biophys Acta. December 9, 1996; 1288 (3): M31-3.


MAD-related proteins in TGF-beta signalling., Wrana JL, Attisano L., Trends Genet. December 1, 1996; 12 (12): 493-6.


[Embryonic induction and role of activins during early amphibian development]., Asashima M, Kinoshita K., Hum Cell. December 1, 1996; 9 (4): 277-82.


Combinatorial signalling by Xwnt-11 and Xnr3 in the organizer epithelium., Glinka A, Delius H, Blumenstock C, Niehrs C., Mech Dev. December 1, 1996; 60 (2): 221-31.          


Cleavage and inactivation of DNA-dependent protein kinase catalytic subunit during apoptosis in Xenopus egg extracts., Le Romancer M, Cosulich SC, Jackson SP, Clarke PR., J Cell Sci. December 1, 1996; 109 ( Pt 13) 3121-7.


Activation of Siamois by the Wnt pathway., Brannon M, Kimelman D., Dev Biol. November 25, 1996; 180 (1): 344-7.


Initiation of vertebrate left-right axis formation by maternal Vg1., Hyatt BA, Lohr JL, Yost HJ., Nature. November 7, 1996; 384 (6604): 62-5.


Signalling by TGF-beta family members: short-range effects of Xnr-2 and BMP-4 contrast with the long-range effects of activin., Jones CM, Armes N, Smith JC., Curr Biol. November 1, 1996; 6 (11): 1468-75.


Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways., Lagna G, Hata A, Hemmati-Brivanlou A, Massagué J., Nature. October 31, 1996; 383 (6603): 832-6.


A transcriptional partner for MAD proteins in TGF-beta signalling., Chen X, Rubock MJ, Whitman M., Nature. October 24, 1996; 383 (6602): 691-6.


Nomenclature: vertebrate mediators of TGFbeta family signals., Derynck R, Gelbart WM, Harland RM, Heldin CH, Kern SE, Massagué J, Melton DA, Mlodzik M, Padgett RW, Roberts AB, Smith J, Thomsen GH, Vogelstein B, Wang XF., Cell. October 18, 1996; 87 (2): 173.


A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation., Lustig KD, Kroll K, Sun E, Ramos R, Elmendorf H, Kirschner MW., Development. October 1, 1996; 122 (10): 3275-82.                


Short-range signaling by candidate morphogens of the TGF beta family and evidence for a relay mechanism of induction., Reilly KM, Melton DA., Cell. September 6, 1996; 86 (5): 743-54.


Immunocytochemical evidence of PDGF- and TGF-beta-like molecules in invertebrate and vertebrate immunocytes: an evolutionary approach., Franchini A, Kletsas D, Ottaviani E., Histochem J. September 1, 1996; 28 (9): 599-605.


MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma., Eppert K, Scherer SW, Ozcelik H, Pirone R, Hoodless P, Kim H, Tsui LC, Bapat B, Gallinger S, Andrulis IL, Thomsen GH, Wrana JL, Attisano L., Cell. August 23, 1996; 86 (4): 543-52.

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