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Summary Expression Phenotypes Gene Literature (500) GO Terms (3) Nucleotides (62) Proteins (38) Interactants (1603) Wiki
XB--483208

Papers associated with nodal



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Smad2 and Smad3 coordinately regulate craniofacial and endodermal development., Liu Y, Festing M, Thompson JC, Hester M, Rankin S, Rankin S, El-Hodiri HM, Zorn AM, Weinstein M., Dev Biol. June 15, 2004; 270 (2): 411-26.  


Xantivin suppresses the activity of EGF-CFC genes to regulate nodal signaling., Tanegashima K, Haramoto Y, Yokota C, Takahashi S, Asashima M., Int J Dev Biol. June 1, 2004; 48 (4): 275-83.          


Multiple signaling pathways control Tbx6 expression during Xenopus myogenesis., Fang PF, Hu RY, He XY, Ding XY., Acta Biochim Biophys Sin (Shanghai). June 1, 2004; 36 (6): 390-6.


Analysis of Spemann organizer formation in Xenopus embryos by cDNA macroarrays., Wessely O, Kim JI, Geissert D, Tran U, De Robertis EM., Dev Biol. May 15, 2004; 269 (2): 552-66.        


Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus., Kuroda H, Wessely O, De Robertis EM., PLoS Biol. May 1, 2004; 2 (5): E92.                


Bone morphogenetic protein-3 family members and their biological functions., Hino J, Kangawa K, Matsuo H, Nohno T, Nishimatsu S., Front Biosci. May 1, 2004; 9 1520-9.


ALK4 functions as a receptor for multiple TGF beta-related ligands to regulate left-right axis determination and mesoderm induction in Xenopus., Chen Y, Mironova E, Whitaker LL, Edwards L, Yost HJ, Ramsdell AF., Dev Biol. April 15, 2004; 268 (2): 280-94.      


Two modes by which Lefty proteins inhibit nodal signaling., Chen C, Shen MM., Curr Biol. April 6, 2004; 14 (7): 618-24.


Notch signaling can regulate endoderm formation in zebrafish., Kikuchi Y, Verkade H, Reiter JF, Kim CH, Chitnis AB, Kuroiwa A, Stainier DY., Dev Dyn. April 1, 2004; 229 (4): 756-62.


The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish., Hashimoto H, Rebagliati M, Ahmad N, Muraoka O, Kurokawa T, Hibi M, Suzuki T., Development. April 1, 2004; 131 (8): 1741-53.


Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors., Cheng SK, Olale F, Brivanlou AH, Schier AF., PLoS Biol. February 1, 2004; 2 (2): E30.                  


Regulation of vertebrate eye development by Rx genes., Bailey TJ, El-Hodiri H, Zhang L, Shah R, Mathers PH, Jamrich M., Int J Dev Biol. January 1, 2004; 48 (8-9): 761-70.    


Dorsal-ventral patterning and neural induction in Xenopus embryos., De Robertis EM, Kuroda H., Annu Rev Cell Dev Biol. January 1, 2004; 20 285-308.


Xenopus tropicalis nodal-related gene 3 regulates BMP signaling: an essential role for the pro-region., Haramoto Y, Tanegashima K, Onuma Y, Takahashi S, Sekizaki H, Asashima M., Dev Biol. January 1, 2004; 265 (1): 155-68.              


An SP1-like transcription factor Spr2 acts downstream of Fgf signaling to mediate mesoderm induction., Zhao J, Cao Y, Zhao C, Postlethwait J, Meng A., EMBO J. November 17, 2003; 22 (22): 6078-88.


Nodal signaling and vertebrate germ layer formation., Weng W, Stemple DL., Birth Defects Res C Embryo Today. November 1, 2003; 69 (4): 325-32.


Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto., Harms PW, Chang C., Genes Dev. November 1, 2003; 17 (21): 2624-9.


The maternally expressed zebrafish T-box gene eomesodermin regulates organizer formation., Bruce AE, Howley C, Zhou Y, Vickers SL, Silver LM, King ML, Ho RK., Development. November 1, 2003; 130 (22): 5503-17.


Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells., Parisi S, D'Andrea D, Lago CT, Adamson ED, Persico MG, Minchiotti G., J Cell Biol. October 27, 2003; 163 (2): 303-14.                    


Activin/Nodal signals mediate the ventral expression of myf-5 in Xenopus gastrula embryos., Chen Y, Lin GF, Hu R, Chen Y, Ding X., Biochem Biophys Res Commun. October 10, 2003; 310 (1): 121-7.


VegT activation of the early zygotic gene Xnr5 requires lifting of Tcf-mediated repression in the Xenopus blastula., Hilton E, Rex M, Old R., Mech Dev. October 1, 2003; 120 (10): 1127-38.


Endogenous Cerberus activity is required for anterior head specification in Xenopus., Silva AC, Filipe M, Kuerner KM, Steinbeisser H, Belo JA., Development. October 1, 2003; 130 (20): 4943-53.              


The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish., Trinh LA, Meyer D, Stainier DY., Development. October 1, 2003; 130 (20): 4989-98.


Fibroblast growth factor receptor-1 is essential for in vitro cardiomyocyte development., Dell'Era P, Ronca R, Coco L, Nicoli S, Metra M, Presta M., Circ Res. September 5, 2003; 93 (5): 414-20.


Left-right asymmetry: nodal points., Mercola M., J Cell Sci. August 15, 2003; 116 (Pt 16): 3251-7.      


Early head specification in Xenopus laevis., Lake BB, Kao KR., ScientificWorldJournal. August 2, 2003; 3 655-76.    


Coordination of BMP-3b and cerberus is required for head formation of Xenopus embryos., Hino J, Nishimatsu S, Nagai T, Matsuo H, Kangawa K, Nohno T., Dev Biol. August 1, 2003; 260 (1): 138-57.                            


Induction of cardiomyocytes by GATA4 in Xenopus ectodermal explants., Latinkić BV, Kotecha S, Mohun TJ., Development. August 1, 2003; 130 (16): 3865-76.              


Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality., Concha ML, Russell C, Regan JC, Tawk M, Sidi S, Gilmour DT, Kapsimali M, Sumoy L, Goldstone K, Amaya E, Kimelman D, Nicolson T, Gründer S, Gomperts M, Clarke JD, Wilson SW., Neuron. July 31, 2003; 39 (3): 423-38.


A role for maternal beta-catenin in early mesoderm induction in Xenopus., Schohl A, Fagotto F., EMBO J. July 1, 2003; 22 (13): 3303-13.


Two variants of zebrafish p100 are expressed during embryogenesis and regulated by Nodal signaling., Zhao CT, Shi KH, Su Y, Liang LY, Yan Y, Postlethwait J, Meng AM., FEBS Lett. May 22, 2003; 543 (1-3): 190-5.


Molecular link in the sequential induction of the Spemann organizer: direct activation of the cerberus gene by Xlim-1, Xotx2, Mix.1, and Siamois, immediately downstream from Nodal and Wnt signaling., Yamamoto S, Hikasa H, Ono H, Taira M., Dev Biol. May 1, 2003; 257 (1): 190-204.


A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor., Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J., Development. May 1, 2003; 130 (10): 2199-212.    


FRL-1, a member of the EGF-CFC family, is essential for neural differentiation in Xenopus early development., Yabe S, Tanegashima K, Haramoto Y, Takahashi S, Fujii T, Kozuma S, Taketani Y, Asashima M., Development. May 1, 2003; 130 (10): 2071-81.


The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia., Watanabe D, Saijoh Y, Nonaka S, Sasaki G, Ikawa Y, Yokoyama T, Hamada H., Development. May 1, 2003; 130 (9): 1725-34.


Regulation of nodal and BMP signaling by tomoregulin-1 (X7365) through novel mechanisms., Chang C, Eggen BJ, Weinstein DC, Brivanlou AH., Dev Biol. March 1, 2003; 255 (1): 1-11.                    


Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity., Take-uchi M, Clarke JD, Wilson SW., Development. March 1, 2003; 130 (5): 955-68.


Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein., Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R., Int J Dev Biol. February 1, 2003; 47 (1): 15-29.                  


EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1., Cheng SK, Olale F, Bennett JT, Brivanlou AH, Schier AF., Genes Dev. January 1, 2003; 17 (1): 31-6.


Nodal signaling in Xenopus gastrulae is cell-autonomous and patterned by beta-catenin., Hashimoto-Partyka MK, Yuge M, Cho KW., Dev Biol. January 1, 2003; 253 (1): 125-38.                    


PKCgamma regulates syndecan-2 inside-out signaling during xenopus left-right development., Kramer KL, Barnette JE, Yost HJ., Cell. December 27, 2002; 111 (7): 981-90.                


Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation., Branford WW, Yost HJ., Curr Biol. December 23, 2002; 12 (24): 2136-41.              


Morphogen gradients, positional information, and Xenopus: interplay of theory and experiment., Green J., Dev Dyn. December 1, 2002; 225 (4): 392-408.


Beta-catenin/Tcf-regulated transcription prior to the midblastula transition., Yang J, Tan C, Darken RS, Wilson PA, Klein PS., Development. December 1, 2002; 129 (24): 5743-52.


Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates endoderm specification in zebrafish., Poulain M, Lepage T., Development. November 1, 2002; 129 (21): 4901-14.


The hypoblast of the chick embryo positions the primitive streak by antagonizing nodal signaling., Bertocchini F, Stern CD., Dev Cell. November 1, 2002; 3 (5): 735-44.


Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning., Levin M, Thorlin T, Robinson KR, Nogi T, Mercola M., Cell. October 4, 2002; 111 (1): 77-89.              


The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus., Kumano G, Smith WC., Mech Dev. October 1, 2002; 118 (1-2): 45-56.    


Molecular regulation of vertebrate early endoderm development., Shivdasani RA., Dev Biol. September 15, 2002; 249 (2): 191-203.      


The roles of three signaling pathways in the formation and function of the Spemann Organizer., Xanthos JB, Kofron M, Tao Q, Tao Q, Schaible K, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4027-43.                  

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