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Summary Expression Phenotypes Gene Literature (500) GO Terms (3) Nucleotides (62) Proteins (38) Interactants (1603) Wiki
XB--483208

Papers associated with nodal



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A component of the ARC/Mediator complex required for TGF beta/Nodal signalling., Kato Y, Habas R, Katsuyama Y, Näär AM, He X., Nature. August 8, 2002; 418 (6898): 641-6.

The latent-TGFbeta-binding-protein-1 (LTBP-1) is expressed in the organizer and regulates nodal and activin signaling., Altmann CR, Chang C, Muñoz-Sanjuán I, Bell E, Heke M, Rifkin DB, Brivanlou AH., Dev Biol. August 1, 2002; 248 (1): 118-27.                  

Conserved function for embryonic nodal cilia., Essner JJ, Vogan KJ, Wagner MK, Tabin CJ, Yost HJ, Brueckner M., Nature. July 4, 2002; 418 (6893): 37-8.

Developmentally modulated cardiac conduction failure in transgenic mice with fetal or postnatal overexpression of DNA nonbinding mutant Nkx2.5., Wakimoto H, Kasahara H, Maguire CT, Izumo S, Berul CI., J Cardiovasc Electrophysiol. July 1, 2002; 13 (7): 682-8.

Effects of heterodimerization and proteolytic processing on Derrière and Nodal activity: implications for mesoderm induction in Xenopus., Eimon PM, Harland RM., Development. July 1, 2002; 129 (13): 3089-103.          

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion., Sakuma R, Ohnishi Yi Y, Meno C, Fujii H, Juan H, Takeuchi J, Ogura T, Li E, Miyazono K, Hamada H., Genes Cells. April 1, 2002; 7 (4): 401-12.

The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling., Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW., Genes Dev. April 1, 2002; 16 (7): 820-35.    

Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-related genes., Rex M, Hilton E, Old R., Int J Dev Biol. March 1, 2002; 46 (2): 217-26.

Xenopus Brachyury regulates mesodermal expression of Zic3, a gene controlling left-right asymmetry., Kitaguchi T, Mizugishi K, Hatayama M, Aruga J, Mikoshiba K., Dev Growth Differ. February 1, 2002; 44 (1): 55-61.        

Multiple nodal-related genes act coordinately in Xenopus embryogenesis., Onuma Y, Takahashi S, Yokota C, Asashima M., Dev Biol. January 1, 2002; 241 (1): 94-105.

Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor., Kramer KL, Yost HJ., Dev Cell. January 1, 2002; 2 (1): 115-24.  

Nodal signaling in early vertebrate embryos: themes and variations., Whitman M., Dev Cell. November 1, 2001; 1 (5): 605-17.

Fucosylation of Cripto is required for its ability to facilitate nodal signaling., Schiffer SG, Foley S, Kaffashan A, Hronowski X, Zichittella AE, Yeo CY, Miatkowski K, Adkins HB, Damon B, Whitman M, Salomon D, Sanicola M, Williams KP., J Biol Chem. October 12, 2001; 276 (41): 37769-78.

Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate embryogenesis., Tiedemann H, Asashima M, Grunz H, Knöchel W., Dev Growth Differ. October 1, 2001; 43 (5): 469-502.

Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo., Erter CE, Wilm TP, Basler N, Wright CV, Solnica-Krezel L., Development. September 1, 2001; 128 (18): 3571-83.

VegT activation of Sox17 at the midblastula transition alters the response to nodal signals in the vegetal endoderm domain., Engleka MJ, Craig EJ, Kessler DS., Dev Biol. September 1, 2001; 237 (1): 159-72.                

Early posterior/ventral fate specification in the vertebrate embryo., Muñoz-Sanjuán I, H-Brivanlou A., Dev Biol. September 1, 2001; 237 (1): 1-17.      

Boundaries and functional domains in the animal/vegetal axis of Xenopus gastrula mesoderm., Kumano G, Ezal C, Smith WC., Dev Biol. August 15, 2001; 236 (2): 465-77.    

Vertebrate development: Et in Arkadia., Patten I, Placzek M., Curr Biol. August 7, 2001; 11 (15): R616-9.

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development., Reissmann E, Jörnvall H, Blokzijl A, Andersson O, Chang C, Minchiotti G, Persico MG, Ibáñez CF, Brivanlou AH., Genes Dev. August 1, 2001; 15 (15): 2010-22.                

Suppression of head formation by Xmsx-1 through the inhibition of intracellular nodal signaling., Yamamoto TS, Takagi C, Hyodo AC, Ueno N., Development. July 1, 2001; 128 (14): 2769-79.      

Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5., Reiter JF, Verkade H, Stainier DY., Dev Biol. June 15, 2001; 234 (2): 330-8.

Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus., Wessely O, Agius E, Oelgeschläger M, Pera EM, De Robertis EM., Dev Biol. June 1, 2001; 234 (1): 161-73.              

Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms., Yeo C, Whitman M., Mol Cell. May 1, 2001; 7 (5): 949-57.

Arkadia enhances nodal-related signalling to induce mesendoderm., Niederländer C, Walsh JJ, Episkopou V, Jones CM., Nature. April 12, 2001; 410 (6830): 830-4.  

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages., Episkopou V, Arkell R, Timmons PM, Walsh JJ, Andrew RL, Swan D., Nature. April 12, 2001; 410 (6830): 825-30.

A role for BMP signalling in heart looping morphogenesis in Xenopus., Breckenridge RA, Mohun TJ, Amaya E., Dev Biol. April 1, 2001; 232 (1): 191-203.          

In synergy with noggin and follistatin, Xenopus nodal-related gene induces sonic hedgehog on notochord and floor plate., Ito Y, Kuhara S, Tashiro K., Biochem Biophys Res Commun. March 2, 2001; 281 (3): 714-9.      

The pitx2 homeobox protein is required early for endoderm formation and nodal signaling. ., Faucourt M, Houliston E, Besnardeau L, Kimelman D, Lepage T., Dev Biol. January 15, 2001; 229 (2): 287-306.                

Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads., Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR., J Biol Chem. January 5, 2001; 276 (1): 656-61.

Functional analysis of the Xenopus frizzled 7 protein domains using chimeric receptors., Swain RK, Medina A, Steinbeisser H., Int J Dev Biol. January 1, 2001; 45 (1): 259-64.

Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2., Shiratori H, Sakuma R, Watanabe M, Hashiguchi H, Mochida K, Sakai Y, Nishino J, Saijoh Y, Whitman M, Hamada H., Mol Cell. January 1, 2001; 7 (1): 137-49.

Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis., Xanthos JB, Kofron M, Wylie C, Heasman J., Development. January 1, 2001; 128 (2): 167-80.

The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer., Saloman DS, Bianco C, Ebert AD, Khan NI, De Santis M, Normanno N, Wechselberger C, Seno M, Williams K, Sanicola M, Foley S, Gullick WJ, Persico G., Endocr Relat Cancer. December 1, 2000; 7 (4): 199-226.

Cloning and expression pattern of a zebrafish homolog of forkhead activin signal transducer (FAST), a transcription factor mediating Nodal-related signals., Boggetti B, Argenton F, Haffter P, Bianchi ME, Cotelli F, Beltrame M., Mech Dev. December 1, 2000; 99 (1-2): 187-90.

Expression cloning of Xantivin, a Xenopus lefty/antivin-related gene, involved in the regulation of activin signaling during mesoderm induction., Tanegashima K, Yokota C, Takahashi S, Asashima M., Mech Dev. December 1, 2000; 99 (1-2): 3-14.  

Two novel nodal-related genes initiate early inductive events in Xenopus Nieuwkoop center., Takahashi S, Yokota C, Takano K, Tanegashima K, Onuma Y, Goto J, Asashima M., Development. December 1, 2000; 127 (24): 5319-29.

Vertebrate development: the fast track to nodal signalling., Stemple DL., Curr Biol. November 16, 2000; 10 (22): R843-6.

Mesendoderm induction and reversal of left-right pattern by mouse Gdf1, a Vg1-related gene., Wall NA, Craig EJ, Labosky PA, Kessler DS., Dev Biol. November 15, 2000; 227 (2): 495-509.              

Zebrafish Dkk1, induced by the pre-MBT Wnt signaling, is secreted from the prechordal plate and patterns the anterior neural plate., Shinya M, Eschbach C, Clark M, Lehrach H, Furutani-Seiki M., Mech Dev. November 1, 2000; 98 (1-2): 3-17.

Zic3 is involved in the left-right specification of the Xenopus embryo., Kitaguchi T, Nagai T, Nakata K, Aruga J, Mikoshiba K., Development. November 1, 2000; 127 (22): 4787-95.              

Bottle cell formation in relation to mesodermal patterning in the Xenopus embryo., Kurth T, Hausen P., Mech Dev. October 1, 2000; 97 (1-2): 117-31.  

Fast1 is required for the development of dorsal axial structures in zebrafish., Sirotkin HI, Gates MA, Kelly PD, Schier AF, Talbot WS., Curr Biol. September 7, 2000; 10 (17): 1051-4.

Interaction of Frizzled 7 and Dishevelled in Xenopus., Medina A, Steinbeisser H., Dev Dyn. August 1, 2000; 218 (4): 671-80.

Regulation of gut and heart left-right asymmetry by context-dependent interactions between xenopus lefty and BMP4 signaling., Branford WW, Essner JJ, Yost HJ., Dev Biol. July 15, 2000; 223 (2): 291-306.              

The TGF-beta family member derrière is involved in regulation of the establishment of left-right asymmetry., Hanafusa H, Masuyama N, Kusakabe M, Shibuya H, Nishida E., EMBO Rep. July 1, 2000; 1 (1): 32-9.

A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction., Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB., Genes Dev. July 1, 2000; 14 (13): 1605-16.            

Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling., Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C., Mech Dev. June 1, 2000; 94 (1-2): 37-46.          

Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1., Osada SI, Saijoh Y, Frisch A, Yeo CY, Adachi H, Watanabe M, Whitman M, Hamada H, Wright CV., Development. June 1, 2000; 127 (11): 2503-14.

The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination., Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, Woychik RP., Development. June 1, 2000; 127 (11): 2347-55.

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