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Summary Expression Phenotypes Gene Literature (242) GO Terms (8) Nucleotides (225) Proteins (62) Interactants (1337) Wiki
XB--482929

Papers associated with smad2



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Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

Sox5 Is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm., Nordin K, LaBonne C., Dev Cell. November 10, 2014; 31 (3): 374-382.                              

Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression., Nelson AC, Cutty SJ, Niini M, Stemple DL, Flicek P, Houart C, Bruce AE, Wardle FC., BMC Biol. October 3, 2014; 12 81.            

Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos., Kirmizitas A, Gillis WQ, Zhu H, Thomsen GH., Dev Biol. August 15, 2014; 392 (2): 358-67.                                

Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos., Chatfield J, O'Reilly MA, Bachvarova RF, Ferjentsik Z, Redwood C, Walmsley M, Patient R, Loose M, Johnson AD., Development. June 1, 2014; 141 (12): 2429-40.              

A potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome., Tanaka K, Kato A, Angelocci C, Watanabe M, Kato Y., Dev Biol. March 1, 2014; 387 (1): 28-36.        

Commitment to nutritional endoderm in Eleutherodactylus coqui involves altered nodal signaling and global transcriptional repression., Chatterjee S, Elinson RP., J Exp Zool B Mol Dev Evol. January 1, 2014; 322 (1): 27-44.

Activin ligands are required for the re-activation of Smad2 signalling after neurulation and vascular development in Xenopus tropicalis., Nagamori Y, Roberts S, Maciej M, Dorey K., Int J Dev Biol. January 1, 2014; 58 (10-12): 783-91.            

Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling., Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E., Development. October 1, 2013; 140 (20): 4177-81.              

RAB8B is required for activity and caveolar endocytosis of LRP6., Demir K, Kirsch N, Beretta CA, Erdmann G, Ingelfinger D, Moro E, Argenton F, Carl M, Niehrs C, Boutros M., Cell Rep. September 26, 2013; 4 (6): 1224-34.                    

In vivo T-box transcription factor profiling reveals joint regulation of embryonic neuromesodermal bipotency., Gentsch GE, Owens ND, Martin SR, Piccinelli P, Faial T, Trotter MW, Gilchrist MJ, Smith JC., Cell Rep. September 26, 2013; 4 (6): 1185-96.                              

TBX3 Directs Cell-Fate Decision toward Mesendoderm., Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.                

A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome., Rienhoff HY, Yeo CY, Morissette R, Khrebtukova I, Melnick J, Luo S, Leng N, Kim YJ, Schroth G, Westwick J, Vogel H, McDonnell N, Hall JG, Whitman M., Am J Med Genet A. August 1, 2013; 161A (8): 2040-6.          

Lin28 proteins are required for germ layer specification in Xenopus., Faas L, Warrander FC, Maguire R, Ramsbottom SA, Quinn D, Genever P, Isaacs HV., Development. March 1, 2013; 140 (5): 976-86.                      

The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1., Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, Winterbottom E, Ji YJ, Singh A, Daar IO., Genes Dev. March 1, 2013; 27 (5): 491-503.                        

Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus., Lim CY, Reversade B, Knowles BB, Solter D., Development. February 1, 2013; 140 (4): 853-60.                                              

A functional genome-wide in vivo screen identifies new regulators of signalling pathways during early Xenopus embryogenesis., Zhang S, Li J, Lea R, Amaya E, Dorey K., PLoS One. January 1, 2013; 8 (11): e79469.              

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis., Colas AR, McKeithan WL, Cunningham TJ, Bushway PJ, Garmire LX, Duester G, Subramaniam S, Mercola M., Genes Dev. December 1, 2012; 26 (23): 2567-79.      

Indirubin derivatives modulate TGFβ/BMP signaling at different levels and trigger ubiquitin-mediated depletion of nonactivated R-Smads., Cheng X, Alborzinia H, Merz KH, Steinbeisser H, Mrowka R, Scholl C, Kitanovic I, Eisenbrand G, Wölfl S., Chem Biol. November 21, 2012; 19 (11): 1423-36.

Brain-specific promoter/exon I.f of the cyp19a1 (aromatase) gene in Xenopus laevis., Nakagawa T, Iwabuchi J., J Steroid Biochem Mol Biol. November 1, 2012; 132 (3-5): 247-55.

Signaling crosstalk between TGFβ and Dishevelled/Par1b., Mamidi A, Inui M, Manfrin A, Soligo S, Enzo E, Aragona M, Cordenonsi M, Wessely O, Dupont S, Piccolo S., Cell Death Differ. October 1, 2012; 19 (10): 1689-97.                    

Conservation and evolutionary divergence in the activity of receptor-regulated smads., Sorrentino GM, Gillis WQ, Oomen-Hajagos J, Thomsen GH., Evodevo. October 1, 2012; 3 (1): 22.              

Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4., Warmflash A, Zhang Q, Sorre B, Vonica A, Siggia ED, Brivanlou AH., Proc Natl Acad Sci U S A. July 10, 2012; 109 (28): E1947-56.          

Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins., Callery EM, Park CY, Xu X, Zhu H, Smith JC, Thomsen GH., Open Biol. April 1, 2012; 2 (4): 120060.                      

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells., Miyazaki A, Ishii K, Yamashita S, Nejigane S, Matsukawa S, Ito Y, Onuma Y, Asashima M, Michiue T., PLoS One. January 1, 2012; 7 (10): e46630.        

An essential role for transcription before the MBT in Xenopus laevis., Skirkanich J, Luxardi G, Yang J, Kodjabachian L, Klein PS., Dev Biol. September 15, 2011; 357 (2): 478-91.        

Inhibition of FGF signaling converts dorsal mesoderm to ventral mesoderm in early Xenopus embryos., Lee SY, Lim SK, Cha SW, Yoon J, Lee SH, Lee HS, Lee HS, Park JB, Lee JY, Kim SC, Kim J., Differentiation. September 1, 2011; 82 (2): 99-107.                    

HEB and E2A function as SMAD/FOXH1 cofactors., Yoon SJ, Wills AE, Chuong E, Gupta R, Baker JC., Genes Dev. August 1, 2011; 25 (15): 1654-61.            

Sortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation., Kwon S, Christian JL., J Biol Chem. June 17, 2011; 286 (24): 21876-85.

A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer., Rankin SA, Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM., Dev Biol. March 15, 2011; 351 (2): 297-310.                            

SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos., Wu MY, Ramel MC, Howell M, Hill CS., PLoS Biol. February 15, 2011; 9 (2): e1000593.                              

SB431542 treatment promotes the hypertrophy of skeletal muscle fibers but decreases specific force., Watt KI, Jaspers RT, Atherton P, Smith K, Rennie MJ, Ratkevicius A, Wackerhage H., Muscle Nerve. May 1, 2010; 41 (5): 624-9.

TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling., Watanabe Y, Itoh S, Goto T, Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L, Tanaka A, Nakano N, Mommaas AM, Shibuya H, Ten Dijke P, Kato M., Mol Cell. January 15, 2010; 37 (1): 123-34.                                      

The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo., Ho DM, Yeo CY, Whitman M., Mech Dev. January 1, 2010; 127 (9-12): 485-95.                  

Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus., Hagemann AI, Xu X, Nentwich O, Hyvonen M, Smith JC., Development. August 1, 2009; 136 (16): 2803-13.                

Riding shotgun: a dual role for the epidermal growth factor-Cripto/FRL-1/Cryptic protein Cripto in Nodal trafficking., Constam DB., Traffic. July 1, 2009; 10 (7): 783-91.

Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos., Cheong SM, Kim H, Han JK., J Biol Chem. June 19, 2009; 284 (25): 17052-60.                        

High-sensitivity real-time imaging of dual protein-protein interactions in living subjects using multicolor luciferases., Hida N, Awais M, Takeuchi M, Ueno N, Tashiro M, Takagi C, Singh T, Hayashi M, Ohmiya Y, Ozawa T., PLoS One. June 12, 2009; 4 (6): e5868.            

Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling., Dai F, Lin X, Chang C, Feng XH., Dev Cell. March 1, 2009; 16 (3): 345-57.

Eomesodermin requires transforming growth factor-beta/activin signaling and binds Smad2 to activate mesodermal genes., Picozzi P, Wang F, Cronk K, Ryan K., J Biol Chem. January 23, 2009; 284 (4): 2397-408.

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination., Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M, Martello G, Stinchfield MJ, Soligo S, Morsut L, Inui M, Moro S, Modena N, Argenton F, Newfeld SJ, Piccolo S., Cell. January 9, 2009; 136 (1): 123-35.  

Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation., Cao Y, Siegel D, Oswald F, Knöchel W., J Biol Chem. December 5, 2008; 283 (49): 34168-77.                

TGF-beta induces connexin43 gene expression in normal murine mammary gland epithelial cells via activation of p38 and PI3K/AKT signaling pathways., Tacheau C, Fontaine J, Loy J, Mauviel A, Verrecchia F., J Cell Physiol. December 1, 2008; 217 (3): 759-68.

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation., Cha SW, Tadjuidje E, Tao Q, Tao Q, Wylie C, Heasman J., Development. November 1, 2008; 135 (22): 3719-29.        

Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling., Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M., Development. September 1, 2008; 135 (17): 2927-37.  

Regulation of activin/nodal signaling by Rap2-directed receptor trafficking., Choi SC, Kim GH, Lee SJ, Park E, Yeo CY, Han JK., Dev Cell. July 1, 2008; 15 (1): 49-61.

Ectodermal factor restricts mesoderm differentiation by inhibiting p53., Sasai N, Yakura R, Kamiya D, Nakazawa Y, Sasai Y., Cell. May 30, 2008; 133 (5): 878-90.                        

p53 regulation orchestrates the TGF-beta response., Piccolo S., Cell. May 30, 2008; 133 (5): 767-9.

Regulation of TGF-(beta) signalling by N-acetylgalactosaminyltransferase-like 1., Herr P, Korniychuk G, Yamamoto Y, Grubisic K, Oelgeschläger M., Development. May 1, 2008; 135 (10): 1813-22.                    

Identification of a novel pool of extracellular pro-myostatin in skeletal muscle., Anderson SB, Goldberg AL, Whitman M., J Biol Chem. March 14, 2008; 283 (11): 7027-35.

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