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Summary Expression Phenotypes Gene Literature (84) GO Terms (6) Nucleotides (95) Proteins (54) Interactants (861) Wiki
XB--485516

Papers associated with lef1



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SALL4 is directly activated by TCF/LEF in the canonical Wnt signaling pathway., Böhm J, Sustmann C, Wilhelm C, Kohlhase J., Biochem Biophys Res Commun. September 29, 2006; 348 (3): 898-907.

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)., Yamada M, Ohnishi J, Ohkawara B, Iemura S, Satoh K, Hyodo-Miura J, Kawachi K, Natsume T, Shibuya H., J Biol Chem. July 28, 2006; 281 (30): 20749-20760.                    

HIC-5 is a novel repressor of lymphoid enhancer factor/T-cell factor-driven transcription., Ghogomu SM, van Venrooy S, Ritthaler M, Wedlich D, Gradl D., J Biol Chem. January 20, 2006; 281 (3): 1755-64.            

Distinct roles for Xenopus Tcf/Lef genes in mediating specific responses to Wnt/beta-catenin signalling in mesoderm development., Liu F, van den Broek O, Destrée O, Hoppler S., Development. December 1, 2005; 132 (24): 5375-85.          

Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability., Ishitani T, Matsumoto K, Chitnis AB, Itoh M., Nat Cell Biol. November 1, 2005; 7 (11): 1106-12.

Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP., Cui Q, Lim SK, Zhao B, Hoffmann FM., Oncogene. June 2, 2005; 24 (24): 3864-74.

PR72, a novel regulator of Wnt signaling required for Naked cuticle function., Creyghton MP, Roël G, Eichhorn PJ, Hijmans EM, Maurer I, Destrée O, Bernards R., Genes Dev. February 1, 2005; 19 (3): 376-86.            

Global inhibition of Lef1/Tcf-dependent Wnt signaling at its nuclear end point abrogates development in transgenic Xenopus embryos., Deroo T, Denayer T, Van Roy F, Vleminckx K, Vleminckx K., J Biol Chem. December 3, 2004; 279 (49): 50670-5.

Cross-regulation of Wnt signaling and cell adhesion., Schambony A, Kunz M, Gradl D., Differentiation. September 1, 2004; 72 (7): 307-18.

Regulation of casein kinase I epsilon activity by Wnt signaling., Swiatek W, Tsai IC, Klimowski L, Pepler A, Barnette J, Yost HJ, Virshup DM., J Biol Chem. March 26, 2004; 279 (13): 13011-7.            

VegT activation of the early zygotic gene Xnr5 requires lifting of Tcf-mediated repression in the Xenopus blastula., Hilton E, Rex M, Old R., Mech Dev. October 1, 2003; 120 (10): 1127-38.

Integration of multiple signal transducing pathways on Fgf response elements of the Xenopus caudal homologue Xcad3., Haremaki T, Tanaka Y, Hongo I, Yuge M, Okamoto H., Development. October 1, 2003; 130 (20): 4907-17.                  

Tcf-1 expression during Xenopus development., Roël G, van den Broek O, Spieker N, Peterson-Maduro J, Destrée O., Gene Expr Patterns. May 1, 2003; 3 (2): 123-6.                

Lef-1 and Tcf-3 transcription factors mediate tissue-specific Wnt signaling during Xenopus development., Roël G, Hamilton FS, Gent Y, Bain AA, Destrée O, Hoppler S., Curr Biol. November 19, 2002; 12 (22): 1941-5.

The LIM-only protein FHL2 interacts with beta-catenin and promotes differentiation of mouse myoblasts., Martin B, Schneider R, Janetzky S, Waibler Z, Pandur P, Kühl M, Behrens J, von der Mark K, Starzinski-Powitz A, Wixler V., J Cell Biol. October 14, 2002; 159 (1): 113-22.                  

Repression through a distal TCF-3 binding site restricts Xenopus myf-5 expression in gastrula mesoderm., Yang J, Mei W, Otto A, Xiao L, Tao Q, Tao Q, Geng X, Rupp RA, Ding X., Mech Dev. July 1, 2002; 115 (1-2): 79-89.              

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways., Labbé E, Letamendia A, Attisano L., Proc Natl Acad Sci U S A. July 18, 2000; 97 (15): 8358-63.

LiCl disrupts axial development in mouse but does not act through the beta-catenin/Lef-1 pathway., Rogers I, Varmuza S., Mol Reprod Dev. April 1, 2000; 55 (4): 387-92.

Tcf/Lef transcription factors during T-cell development: unique and overlapping functions., Staal FJ, Clevers H., Hematol J. January 1, 2000; 1 (1): 3-6.

New steps in the Wnt/beta-catenin signal transduction pathway., Sakanaka C, Sun TQ, Williams LT., Recent Prog Horm Res. January 1, 2000; 55 225-36.

Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates., Moriguchi T, Kawachi K, Kamakura S, Masuyama N, Yamanaka H, Matsumoto K, Kikuchi A, Nishida E., J Biol Chem. October 22, 1999; 274 (43): 30957-62.        

Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin., Zorn AM, Barish GD, Williams BO, Lavender P, Klymkowsky MW, Varmus HE., Mol Cell. October 1, 1999; 4 (4): 487-98.                

Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling., Klymkowsky MW, Williams BO, Barish GD, Varmus HE, Vourgourakis YE., Mol Biol Cell. October 1, 1999; 10 (10): 3151-69.

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1., Li L, Yuan H, Weaver CD, Mao J, Farr GH, Sussman DJ, Jonkers J, Kimelman D, Wu D., EMBO J. August 2, 1999; 18 (15): 4233-40.

Maternal and embryonic expression of zebrafish lef1., Dorsky RI, Snyder A, Cretekos CJ, Grunwald DJ, Geisler R, Haffter P, Moon RT, Raible DW., Mech Dev. August 1, 1999; 86 (1-2): 147-50.

XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development., Brannon M, Brown JD, Bates R, Kimelman D, Moon RT., Development. June 1, 1999; 126 (14): 3159-70.                  

The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis., Vleminckx K, Vleminckx K, Kemler R, Hecht A., Mech Dev. March 1, 1999; 81 (1-2): 65-74.    

A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation., Lee YJ, Swencki B, Shoichet S, Shivdasani RA., J Biol Chem. January 15, 1999; 274 (3): 1566-72.  

Differential expression of the HMG box transcription factors XTcf-3 and XLef-1 during early xenopus development., Molenaar M, Roose J, Peterson J, Venanzi S, Clevers H, Destrée O., Mech Dev. July 1, 1998; 75 (1-2): 151-4.          

LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter., McKendry R, Hsu SC, Harland RM, Grosschedl R., Dev Biol. December 15, 1997; 192 (2): 420-31.            

The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer., Laurent MN, Blitz IL, Hashimoto C, Rothbächer U, Cho KW., Development. December 1, 1997; 124 (23): 4905-16.

The HMG-box mitochondrial transcription factor xl-mtTFA binds DNA as a tetramer to activate bidirectional transcription., Antoshechkin I, Bogenhagen DF, Mastrangelo IA., EMBO J. June 2, 1997; 16 (11): 3198-206.

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1., Huber O, Korn R, McLaughlin J, Ohsugi M, Herrmann BG, Kemler R., Mech Dev. September 1, 1996; 59 (1): 3-10.

Functional interaction of beta-catenin with the transcription factor LEF-1., Behrens J, von Kries JP, Kühl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W., Nature. August 15, 1996; 382 (6592): 638-42.

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