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Summary Expression Phenotypes Gene Literature (210) GO Terms (13) Nucleotides (112) Proteins (49) Interactants (828) Wiki
XB--487801

Papers associated with cdkn1a



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Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis., Bompard G, Rabeharivelo G, Frank M, Cau J, Delsert C, Morin N., J Cell Biol. September 6, 2010; 190 (5): 807-22.                    

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.              

The CRL4Cdt2 ubiquitin ligase mediates the proteolysis of cyclin-dependent kinase inhibitor Xic1 through a direct association with PCNA., Kim DH, Budhavarapu VN, Herrera CR, Nam HW, Kim YS, Yew PR., Mol Cell Biol. September 1, 2010; 30 (17): 4120-33.

Identification of a novel inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1)-mediated methylation of histone H3 Arg-17., Selvi BR, Batta K, Kishore AH, Mantelingu K, Varier RA, Balasubramanyam K, Pradhan SK, Dasgupta D, Sriram S, Agrawal S, Kundu TK., J Biol Chem. March 5, 2010; 285 (10): 7143-52.

Negative feedback regulation of Wnt4 signaling by EAF1 and EAF2/U19., Wan X, Ji W, Mei X, Zhou J, Liu JX, Fang C, Xiao W., PLoS One. February 9, 2010; 5 (2): e9118.                  

ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel., Barro-Soria R, Aldehni F, Almaça J, Witzgall R, Schreiber R, Kunzelmann K., Pflugers Arch. February 1, 2010; 459 (3): 485-97.

TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling., Watanabe Y, Itoh S, Goto T, Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L, Tanaka A, Nakano N, Mommaas AM, Shibuya H, Ten Dijke P, Kato M., Mol Cell. January 15, 2010; 37 (1): 123-34.                                      

Normal levels of p27 are necessary for somite segmentation and determining pronephric organ size., Naylor RW, Collins RJ, Philpott A, Jones EA., Organogenesis. October 1, 2009; 5 (4): 201-10.                                          

Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2., Havens CG, Walter JC., Mol Cell. July 10, 2009; 35 (1): 93-104.

Role of p21-activated kinase in cell polarity and directional mesendoderm migration in the Xenopus gastrula., Nagel M, Luu O, Bisson N, Macanovic B, Moss T, Winklbauer R., Dev Dyn. July 1, 2009; 238 (7): 1709-26.  

Effects of the anthelmintic drug PF1022A on mammalian tissue and cells., Dornetshuber R, Kamyar MR, Rawnduzi P, Baburin I, Kouri K, Pilz E, Hornbogen T, Zocher R, Berger W, Lemmens-Gruber R., Biochem Pharmacol. April 15, 2009; 77 (8): 1437-44.

Xenopus NM23-X4 regulates retinal gliogenesis through interaction with p27Xic1., Mochizuki T, Bilitou A, Waters CT, Hussain K, Zollo M, Ohnuma S., Neural Dev. January 5, 2009; 4 1.                      

The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties., Kreis P, Rousseau V, Thévenot E, Combeau G, Barnier JV., J Neurochem. August 1, 2008; 106 (3): 1184-97.

Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase., Adler V, Bowne W, Michl J, Sookraj KA, Ikram K, Pestka S, Izotova L, Zenilman M, Friedman FK, Qu Y, Pincus MR., Ann Clin Lab Sci. January 1, 2008; 38 (1): 47-56.

Molecular cloning and characterisation of SmSLK, a novel Ste20-like kinase in Schistosoma mansoni., Yan Y, Tulasne D, Browaeys E, Cailliau K, Khayath N, Pierce RJ, Trolet J, Fafeur V, Ben Younes A, Dissous C., Int J Parasitol. December 1, 2007; 37 (14): 1539-50.

Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer., Villiard E, Brinkmann H, Moiseeva O, Mallette FA, Ferbeyre G, Roy S., BMC Evol Biol. September 28, 2007; 7 180.              

The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type--but not by oncogenic--ras-p21 protein., Qu Y, Adler V, Izotova L, Pestka S, Bowne W, Michl J, Boutjdir M, Friedman FK, Pincus MR., Front Biosci. September 1, 2007; 12 5089-97.

Tumorhead distribution to cytoplasmic membrane of neural plate cells is positively regulated by Xenopus p21-activated kinase 1 (X-PAK1)., Wu CF, Delsert C, Faure S, Traverso EE, Kloc M, Kuang J, Etkin LD, Morin N., Dev Biol. August 1, 2007; 308 (1): 169-86.              

Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development., Luo T, Xu Y, Xu Y, Hoffman TL, Zhang T, Schilling T, Sargent TD., Development. April 1, 2007; 134 (7): 1279-89.      

Linking PCNA-dependent replication and ATR by human Claspin., Brondello JM, Ducommun B, Fernandez A, Lamb NJ., Biochem Biophys Res Commun. March 23, 2007; 354 (4): 1028-33.

Actin turnover-dependent fast dissociation of capping protein in the dendritic nucleation actin network: evidence of frequent filament severing., Miyoshi T, Tsuji T, Higashida C, Hertzog M, Fujita A, Narumiya S, Scita G, Watanabe N., J Cell Biol. December 18, 2006; 175 (6): 947-55.              

Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes., Qu Y, Adler V, Chu T, Platica O, Michl J, Pestka S, Izotova L, Boutjdir M, Pincus MR., Front Biosci. September 1, 2006; 11 2420-7.

De novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts., Zembutsu A, Waga S., Nucleic Acids Res. July 26, 2006; 34 (13): e91.          

Mxi1 is essential for neurogenesis in Xenopus and acts by bridging the pan-neural and proneural genes., Klisch TJ, Souopgui J, Juergens K, Rust B, Pieler T, Henningfeld KA., Dev Biol. April 15, 2006; 292 (2): 470-85.                

Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts., Leach CA, Michael WM., J Cell Biol. December 19, 2005; 171 (6): 947-54.                

Src-dependent tyrosine phosphorylation at the tips of growth cone filopodia promotes extension., Robles E, Woo S, Gomez TM., J Neurosci. August 17, 2005; 25 (33): 7669-81.

Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway., Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung HF, Lin M, Friedman FK, Chie L, Chung D, Boutjdir M, Pincus MR., Biochemistry. August 16, 2005; 44 (32): 10784-95.

Specificity of inhibition of ras-p21 signal transduction by peptides from GTPase activating protein (GAP) and the son-of sevenless (SOS) ras-specific guanine nucleotide exchange protein., Chie L, Chung D, Pincus MR., Protein J. May 1, 2005; 24 (4): 253-8.

Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1., Etard C, Gradl D, Kunz M, Eilers M, Wedlich D., Mech Dev. April 1, 2005; 122 (4): 545-56.                    

Xenopus p21-activated kinase 5 regulates blastomeres' adhesive properties during convergent extension movements., Faure S, Cau J, de Santa Barbara P, Bigou S, Ge Q, Delsert C, Morin N., Dev Biol. January 15, 2005; 277 (2): 472-92.    

Identification of Xenopus cyclin-dependent kinase inhibitors, p16Xic2 and p17Xic3., Daniels M, Dhokia V, Richard-Parpaillon L, Ohnuma S., Gene. November 10, 2004; 342 (1): 41-7.                

DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process., Shechter D, Ying CY, Gautier J., J Biol Chem. October 29, 2004; 279 (44): 45586-93.

A hypophosphorylated form of RPA34 is a specific component of pre-replication centers., Françon P, Lemaître JM, Dreyer C, Maiorano D, Cuvier O, Méchali M., J Cell Sci. October 1, 2004; 117 (Pt 21): 4909-20.                      

Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins., Pincus MR., Front Biosci. September 1, 2004; 9 3486-509.

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication., Jares P, Luciani MG, Blow JJ., BMC Mol Biol. June 28, 2004; 5 5.          

An effector peptide from glutathione-S-transferase-pi strongly and selectively blocks mitotic signaling by oncogenic ras-p21., Chie L, Adler V, Friedman FK, Chung D, Pincus MR., Protein J. April 1, 2004; 23 (3): 235-8.

Loop domain peptides from the SOS ras-guanine nucleotide exchange protein, identified from molecular dynamics calculations, strongly inhibit ras signaling., Chie L, Friedman FK, Duncan T, Chen JM, Chung D, Pincus M., Protein J. April 1, 2004; 23 (3): 229-34.

Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells., De Bosscher K, Hill CS, Nicolás FJ., Biochem J. April 1, 2004; 379 (Pt 1): 209-16.

Oncogenic and activated wild-type ras-p21 proteins induce different isoforms of protein kinase C in mitogenic signal transduction., Chie L, Qu Y, Chung D, Boutjdir M, Pincus MR., J Protein Chem. November 1, 2003; 22 (7-8): 625-9.

PAK interacts with NCK and MLK2 to regulate the activation of jun N-terminal kinase., Poitras L, Jean S, Islam N, Moss T., FEBS Lett. May 22, 2003; 543 (1-3): 129-35.

Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition., Tran NH, Frost JA., J Biol Chem. March 28, 2003; 278 (13): 11221-6.

A protein methyl transferase, PRMT5, selectively blocks oncogenic ras-p21 mitogenic signal transduction., Chie L, Cook JR, Chung D, Hoffmann R, Yang Z, Kim Y, Pestka S, Pincus MR., Ann Clin Lab Sci. January 1, 2003; 33 (2): 200-7.

XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis., Souopgui J, Sölter M, Pieler T., EMBO J. December 2, 2002; 21 (23): 6429-39.

Identification of the site of inhibition of mitogenic signaling by oncogenic ras-p21 by a ras effector peptide., Chie L, Friedman FK, Kung HF, Lin MC, Chung D, Pincus MR., J Protein Chem. July 1, 2002; 21 (5): 367-70.

Inhibition of ras-induced oocyte maturation by peptides from ras-p21 and GTPase activating protein (GAP) identified as being effector domains from molecular dynamics calculations., Friedman FK, Chie L, Chung D, Robinson R, Brandt-Rauf P, Yamaizumi Z, Pincus MR., J Protein Chem. July 1, 2002; 21 (5): 361-6.

Expression of geminin as a marker of cell proliferation in normal tissues and malignancies., Wohlschlegel JA, Kutok JL, Weng AP, Dutta A., Am J Pathol. July 1, 2002; 161 (1): 267-73.

Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication., You Z, Harvey K, Kong L, Newport J., Genes Dev. May 15, 2002; 16 (10): 1182-94.

Molecular cloning and characterization of Strabismus 2 (STB2)., Katoh M., Int J Oncol. May 1, 2002; 20 (5): 993-8.

Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation., Wei L, Imanaka-Yoshida K, Wang L, Zhan S, Schneider MD, DeMayo FJ, Schwartz RJ., Development. April 1, 2002; 129 (7): 1705-14.

A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization., Cau J, Faure S, Comps M, Delsert C, Morin N., J Cell Biol. December 10, 2001; 155 (6): 1029-42.                    

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