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Summary Expression Phenotypes Gene Literature (114) GO Terms (3) Nucleotides (247) Proteins (43) Interactants (652) Wiki
XB--5755356

Papers associated with slc2a1



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referenced by:

Cysteine-scanning mutagenesis and substituted cysteine accessibility analysis of transmembrane segment 4 of the Glut1 glucose transporter., Mueckler M, Makepeace C., J Biol Chem. November 25, 2005; 280 (47): 39562-8.

Microarray-based identification of VegT targets in Xenopus., Taverner NV, Kofron M, Kofron M, Shin Y, Kabitschke C, Gilchrist MJ, Wylie C, Cho KW, Heasman J, Smith JC., Mech Dev. March 1, 2005; 122 (3): 333-54.                                          

6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways., Corpe CP, Lee JH, Lee JH, Kwon O, Eck P, Narayanan J, Kirk KL, Levine M., J Biol Chem. February 18, 2005; 280 (7): 5211-20.

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity., Hertel J, Struthers H, Horj CB, Hruz PW., J Biol Chem. December 31, 2004; 279 (53): 55147-52.

Transmembrane segment 3 of the Glut1 glucose transporter is an outer helix., Mueckler M, Roach W, Makepeace C., J Biol Chem. November 5, 2004; 279 (45): 46876-81.

Relative proximity and orientation of helices 4 and 8 of the GLUT1 glucose transporter., Alisio A, Mueckler M., J Biol Chem. June 18, 2004; 279 (25): 26540-5.

Analysis of transmembrane segment 8 of the GLUT1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility., Mueckler M, Makepeace C., J Biol Chem. March 12, 2004; 279 (11): 10494-9.

Cysteine-scanning mutagenesis of transmembrane segment 1 of glucose transporter GLUT1: extracellular accessibility of helix positions., Heinze M, Monden I, Keller K., Biochemistry. February 3, 2004; 43 (4): 931-6.

Functional studies of threonine 310 mutations in Glut1: T310I is pathogenic, causing Glut1 deficiency., Wang D, Pascual JM, Iserovich P, Yang H, Ma L, Kuang K, Zuniga FA, Sun RP, Swaroop KM, Fischbarg J, De Vivo DC., J Biol Chem. December 5, 2003; 278 (49): 49015-21.

Functional consequences of an in vivo mutation in exon 10 of the human GLUT1 gene., Lange P, Gertsen E, Monden I, Klepper J, Keller K., FEBS Lett. December 4, 2003; 555 (2): 274-8.

Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 (RSC1A1) is dependent on dynamin and protein kinase C., Veyhl M, Wagner CA, Gorboulev V, Schmitt BM, Lang F, Koepsell H., J Membr Biol. November 1, 2003; 196 (1): 71-81.

Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters., Bormans GM, Van Oosterwyck G, De Groot TJ, Veyhl M, Mortelmans L, Verbruggen AM, Koepsell H., J Nucl Med. July 1, 2003; 44 (7): 1075-81.

Validation of the hexose transporter of Plasmodium falciparum as a novel drug target., Joet T, Eckstein-Ludwig U, Morin C, Krishna S., Proc Natl Acad Sci U S A. June 24, 2003; 100 (13): 7476-9.

Mutational analysis of the hexose transporter of Plasmodium falciparum and development of a three-dimensional model., Manning SK, Woodrow C, Zuniga FA, Iserovich P, Fischbarg J, Louw AI, Krishna S., J Biol Chem. August 23, 2002; 277 (34): 30942-9.

Changes in glucose transport and water permeability resulting from the T310I pathogenic mutation in Glut1 are consistent with two transport channels per monomer., Iserovich P, Wang D, Ma L, Yang H, Zuniga FA, Pascual JM, Kuang K, De Vivo DC, Fischbarg J., J Biol Chem. August 23, 2002; 277 (34): 30991-7.  

GLUT2 is a high affinity glucosamine transporter., Uldry M, Ibberson M, Hosokawa M, Thorens B., FEBS Lett. July 31, 2002; 524 (1-3): 199-203.

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations., Murata H, Hruz PW, Mueckler M., AIDS. April 12, 2002; 16 (6): 859-63.

Analysis of transmembrane segment 10 of the Glut1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility., Mueckler M, Makepeace C., J Biol Chem. February 1, 2002; 277 (5): 3498-503.

The large cytoplasmic loop of the glucose transporter GLUT1 is an essential structural element for function., Monden I, Olsowski A, Krause G, Keller K., Biol Chem. November 1, 2001; 382 (11): 1551-8.

Rainbow trout glucose transporter (OnmyGLUT1): functional assessment in Xenopus laevis oocytes and expression in fish embryos., Teerijoki H, Krasnov A, Gorodilov Y, Krishna S, Mölsä H., J Exp Biol. August 1, 2001; 204 (Pt 15): 2667-73.

The predicted ATP-binding domains in the hexose transporter GLUT1 critically affect transporter activity., Liu Q, Vera JC, Peng H, Golde DW., Biochemistry. July 3, 2001; 40 (26): 7874-81.

Functional consequences of the autosomal dominant G272A mutation in the human GLUT1 gene., Klepper J, Monden I, Guertsen E, Voit T, Willemsen M, Keller K., FEBS Lett. June 1, 2001; 498 (1): 104-9.

Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1., Dawson PA, Mychaleckyj JC, Fossey SC, Mihic SJ, Craddock AL, Bowden DW., Mol Genet Metab. January 1, 2001; 74 (1-2): 186-99.

Dehydroascorbic acid transport by GLUT4 in Xenopus oocytes and isolated rat adipocytes., Rumsey SC, Daruwala R, Al-Hasani H, Zarnowski MJ, Simpson IA, Levine M., J Biol Chem. September 8, 2000; 275 (36): 28246-53.

Cysteine-scanning mutagenesis of transmembrane segment 11 of the GLUT1 facilitative glucose transporter., Hruz PW, Mueckler MM., Biochemistry. August 8, 2000; 39 (31): 9367-72.

The mechanism of insulin resistance caused by HIV protease inhibitor therapy., Murata H, Hruz PW, Mueckler M., J Biol Chem. July 7, 2000; 275 (27): 20251-4.

Cysteine scanning mutagenesis of helices 2 and 7 in GLUT1 identifies an exofacial cleft in both transmembrane segments., Olsowski A, Monden I, Krause G, Keller K., Biochemistry. March 14, 2000; 39 (10): 2469-74.

Constitutively active mitogen-activated protein kinase kinase increases GLUT1 expression and recruits both GLUT1 and GLUT4 at the cell surface in 3T3-L1 adipocytes., Yamamoto Y, Yoshimasa Y, Koh M, Suga J, Masuzaki H, Ogawa Y, Hosoda K, Nishimura H, Watanabe Y, Inoue G, Nakao K., Diabetes. March 1, 2000; 49 (3): 332-9.

GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues., Ibberson M, Uldry M, Thorens B., J Biol Chem. February 18, 2000; 275 (7): 4607-12.

Cysteine-scanning mutagenesis of transmembrane segment 7 of the GLUT1 glucose transporter., Hruz PW, Mueckler MM., J Biol Chem. December 17, 1999; 274 (51): 36176-80.

Selective expression of the large neutral amino acid transporter at the blood-brain barrier., Boado RJ, Li JY, Nagaya M, Zhang C, Pardridge WM., Proc Natl Acad Sci U S A. October 12, 1999; 96 (21): 12079-84.

A conserved amino acid motif (R-X-G-R-R) in the Glut1 glucose transporter is an important determinant of membrane topology., Sato M, Mueckler M., J Biol Chem. August 27, 1999; 274 (35): 24721-5.

Specificity of ascorbate analogs for ascorbate transport. Synthesis and detection of [(125)I]6-deoxy-6-iodo-L-ascorbic acid and characterization of its ascorbate-specific transport properties., Rumsey SC, Welch RW, Garraffo HM, Ge P, Lu SF, Crossman AT, Kirk KL, Levine M., J Biol Chem. August 13, 1999; 274 (33): 23215-22.

Transmembrane segment 5 of the Glut1 glucose transporter is an amphipathic helix that forms part of the sugar permeation pathway., Mueckler M, Makepeace C., J Biol Chem. April 16, 1999; 274 (16): 10923-6.

Cysteine-scanning mutagenesis of flanking regions at the boundary between external loop I or IV and transmembrane segment II or VII in the GLUT1 glucose transporter., Olsowski A, Monden I, Keller K., Biochemistry. July 28, 1998; 37 (30): 10738-45.

Identification of an amino acid residue that lies between the exofacial vestibule and exofacial substrate-binding site of the Glut1 sugar permeation pathway., Mueckler M, Makepeace C., J Biol Chem. November 28, 1997; 272 (48): 30141-6.

Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid., Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M., J Biol Chem. July 25, 1997; 272 (30): 18982-9.

Heterologous expression of rab4 reduces glucose transport and GLUT4 abundance at the cell surface in oocytes., Mora S, Monden I, Zorzano A, Keller K., Biochem J. June 1, 1997; 324 ( Pt 2) 455-9.

C-terminal mutations that alter the turnover number for 3-O-methylglucose transport by GLUT1 and GLUT4., Dauterive R, Laroux S, Bunn RC, Chaisson A, Sanson T, Reed BC., J Biol Chem. May 10, 1996; 271 (19): 11414-21.

Insulin and insulin-like growth factor I (IGF-I) stimulate GLUT4 glucose transporter translocation in Xenopus oocytes., Mora S, Kaliman P, Chillarón J, Testar X, Palacín M, Zorzano A., Biochem J. October 1, 1995; 311 ( Pt 1) 59-65.

From triple cysteine mutants to the cysteine-less glucose transporter GLUT1: a functional analysis., Wellner M, Monden I, Keller K., FEBS Lett. August 14, 1995; 370 (1-2): 19-22.

Role of the C-terminal tail of the GLUT1 glucose transporter in its expression and function in Xenopus laevis oocytes., Due AD, Qu ZC, Thomas JM, Buchs A, Powers AC, May JM., Biochemistry. April 25, 1995; 34 (16): 5462-71.

A "cysteineless" GLUT1 glucose transporter has normal function when expressed in Xenopus oocytes., Due AD, Cook JA, Fletcher SJ, Qu ZC, Powers AC, May JM., Biochem Biophys Res Commun. March 17, 1995; 208 (2): 590-6.

Functional consequences of proline mutations in the putative transmembrane segments 6 and 10 of the glucose transporter GLUT1., Wellner M, Monden I, Mueckler MM, Keller K., Eur J Biochem. January 15, 1995; 227 (1-2): 454-8.

Discrete structural domains determine differential endoplasmic reticulum to Golgi transit times for glucose transporter isoforms., Hresko RC, Murata H, Marshall BA, Mueckler M., J Biol Chem. December 23, 1994; 269 (51): 32110-9.

Characterization of glucose transport and cloning of a hexose transporter gene in Trypanosoma cruzi., Tetaud E, Bringaud F, Chabas S, Barrett MP, Baltz T., Proc Natl Acad Sci U S A. August 16, 1994; 91 (17): 8278-82.

Glutamine 161 of Glut1 glucose transporter is critical for transport activity and exofacial ligand binding., Mueckler M, Weng W, Kruse M., J Biol Chem. August 12, 1994; 269 (32): 20533-8.

Production of functional GLUT1 by co-expression of N- and C-terminal half molecules in Xenopus oocytes., Preston RA, Sami AJ, Charalambous BM, Baldwin SA., Biochem Soc Trans. August 1, 1994; 22 (3): 276S.

The role of cysteine residues in glucose-transporter-GLUT1-mediated transport and transport inhibition., Wellner M, Monden I, Keller K., Biochem J. May 1, 1994; 299 ( Pt 3) 813-7.

Evidence that facilitative glucose transporters may fold as beta-barrels., Fischbarg J, Cheung M, Czegledy F, Li J, Iserovich P, Kuang K, Hubbard J, Garner M, Rosen OM, Golde DW., Proc Natl Acad Sci U S A. December 15, 1993; 90 (24): 11658-62.

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