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Summary Expression Phenotypes Gene Literature (226) GO Terms (6) Nucleotides (305) Proteins (73) Interactants (445) Wiki
XB--921634

Papers associated with gnao1



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Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels., Tan PS, Perry MD, Ng CA, Vandenberg JI, Hill AP., J Gen Physiol. September 1, 2012; 140 (3): 293-306.                

Acute alteration of cardiac ECG, action potential, I(Kr) and the human ether-a-go-go-related gene (hERG) K+ channel by PCB 126 and PCB 77., Park MH, Park WS, Jo SH., Toxicol Appl Pharmacol. July 1, 2012; 262 (1): 60-9.

Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis., Van Slyke AC, Cheng YM, Mafi P, Allard CR, Hull CM, Shi YP, Claydon TW., Am J Physiol Cell Physiol. June 15, 2012; 302 (12): C1797-806.

Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migration., Theveneau E, Mayor R., Dev Biol. June 1, 2012; 366 (1): 34-54.

Melatonin receptors are anatomically organized to modulate transmission specifically to cone pathways in the retina of Xenopus laevis., Wiechmann AF, Sherry DM., J Comp Neurol. April 15, 2012; 520 (6): 1115-27.                  

The Xenopus retinal ganglion cell as a model neuron to study the establishment of neuronal connectivity., McFarlane S, Lom B., Dev Neurobiol. April 1, 2012; 72 (4): 520-36.

Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2., Aidery P, Kisselbach J, Gaspar H, Baldea I, Schweizer PA, Becker R, Katus HA, Thomas D., Biochem Biophys Res Commun. February 24, 2012; 418 (4): 830-5.

Pharmacophore modeling for hERG channel facilitation., Yamakawa Y, Furutani K, Inanobe A, Ohno Y, Kurachi Y., Biochem Biophys Res Commun. February 3, 2012; 418 (1): 161-6.

A unified anatomy ontology of the vertebrate skeletal system., Dahdul WM, Balhoff JP, Blackburn DC, Diehl AD, Haendel MA, Hall BK, Lapp H, Lundberg JG, Mungall CJ, Ringwald M, Segerdell E, Van Slyke CE, Vickaryous MK, Westerfield M, Mabee PM., PLoS One. January 1, 2012; 7 (12): e51070.            

Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway., Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M., J Biol Chem. November 11, 2011; 286 (45): 39091-9.

Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells., Schuster AM, Glassmeier G, Bauer CK., Mol Pharmacol. November 1, 2011; 80 (5): 930-42.

Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide., Garg V, Stary-Weinzinger A, Sachse F, Sanguinetti MC., Mol Pharmacol. October 1, 2011; 80 (4): 630-7.

Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo., Charalambous A, Antoniades I, Christodoulou N, Skourides PA., J Nanobiotechnology. September 15, 2011; 9 37.              

Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration., Lee BH, Lee SH, Chu D, Hyun JW, Choe H, Choi BH, Jo SH., Acta Pharmacol Sin. September 1, 2011; 32 (9): 1128-37.                  

Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant., Es-Salah-Lamoureux Z, Xiong PY, Goodchild SJ, Ahern CA, Fedida D., Biophys J. August 3, 2011; 101 (3): 662-70.

Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction., Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Jo SH, Choe H, Nah SY., Eur J Pharmacol. August 1, 2011; 663 (1-3): 59-67.

Differential effects of ginsenoside metabolites on HERG k channel currents., Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Oh JW, Bae CS, Lee SH, Nah SY., J Ginseng Res. June 1, 2011; 35 (2): 191-9.        

Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channel., de la Peña P, Alonso-Ron C, Machín A, Fernández-Trillo J, Carretero L, Domínguez P, Barros F., J Biol Chem. May 27, 2011; 286 (21): 19065-75.

hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds., Hishigaki H, Kuhara S., Database (Oxford). May 17, 2011; 2011 bar017.            

Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids., Grevellec A, Graham A, Tucker AS., Dev Biol. May 15, 2011; 353 (2): 194-205.

hERG potassium channel gating is mediated by N- and C-terminal region interactions., Gustina AS, Trudeau MC., J Gen Physiol. March 1, 2011; 137 (3): 315-25.              

Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643., Grunnet M, Abbruzzese J, Sachse FB, Sanguinetti MC., Mol Pharmacol. January 1, 2011; 79 (1): 1-9.

Inner/Outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis., Fichtman B, Ramos C, Rasala B, Harel A, Forbes DJ., Mol Biol Cell. December 1, 2010; 21 (23): 4197-211.                

Current inhibition of human EAG1 potassium channels by the Ca2+ binding protein S100B., Sahoo N, Tröger J, Heinemann SH, Schönherr R., FEBS Lett. September 24, 2010; 584 (18): 3896-900.

Modification of hERG1 channel gating by Cd2+., Abbruzzese J, Sachse FB, Tristani-Firouzi M, Sanguinetti MC., J Gen Physiol. August 1, 2010; 136 (2): 203-24.                                        

Regulation of the voltage-insensitive step of HERG activation by extracellular pH., Zhou Q, Bett GC., Am J Physiol Heart Circ Physiol. June 1, 2010; 298 (6): H1710-8.

Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening., Lin MC, Abramson J, Papazian DM., J Gen Physiol. May 1, 2010; 135 (5): 415-31.                    

The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism., Gessner G, Macianskiene R, Starkus JG, Schönherr R, Heinemann SH., Eur J Pharmacol. April 25, 2010; 632 (1-3): 52-9.

Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine., Hong HK, Park MH, Lee BH, Jo SH., Biochem Biophys Res Commun. April 9, 2010; 394 (3): 536-41.

Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652., Xing J, Ma J, Zhang P, Fan X., Eur J Pharmacol. March 25, 2010; 630 (1-3): 1-9.

Dynamic expression of axon guidance cues required for optic tract development is controlled by fibroblast growth factor signaling., Atkinson-Leadbeater K, Bertolesi GE, Hehr CL, Webber CA, Cechmanek PB, McFarlane S., J Neurosci. January 13, 2010; 30 (2): 685-93.            

Studies on Xenopus laevis intestine reveal biological pathways underlying vertebrate gut adaptation from embryo to adult., Heimeier RA, Das B, Buchholz DR, Fiorentino M, Shi YB., Genome Biol. January 1, 2010; 11 (5): R55.                    

Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa., Hong HK, Yoon WJ, Kim YH, Yoo ES, Jo SH., J Korean Med Sci. December 1, 2009; 24 (6): 1089-98.            

PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance., Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 20075-80.

The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel., Yang YC, Hsieh JY, Kuo CC., J Gen Physiol. August 1, 2009; 134 (2): 95-113.                      

Divalent cations slow activation of EAG family K+ channels through direct binding to S4., Zhang X, Bursulaya B, Lee CC, Lee CC, Chen B, Pivaroff K, Jegla T., Biophys J. July 8, 2009; 97 (1): 110-20.

Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine., Hong HK, Jo SH., Korean J Physiol Pharmacol. June 1, 2009; 13 (3): 215-20.

Resources and transgenesis techniques for functional genomics in Xenopus., Ogino H, Ochi H., Dev Growth Differ. May 1, 2009; 51 (4): 387-401.      

Biophysical properties of zebrafish ether-à-go-go related gene potassium channels., Scholz EP, Niemer N, Hassel D, Zitron E, Bürgers HF, Bloehs R, Seyler C, Scherer D, Thomas D, Kathöfer S, Katus HA, Rottbauer WA, Karle CA., Biochem Biophys Res Commun. April 3, 2009; 381 (2): 159-64.

Specificity of Gbetagamma signaling depends on Galpha subunit coupling with G-protein-sensitive K(+) channels., Geng X, Du XN, Rusinova R, Liu BY, Li F, Zhang X, Chen XJ, Logothetis DE, Zhang HL., Pharmacology. January 1, 2009; 84 (2): 82-90.

CaM kinase II initiates meiotic spindle depolymerization independently of APC/C activation., Reber S, Over S, Kronja I, Gruss OJ., J Cell Biol. December 15, 2008; 183 (6): 1007-17.            

Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin., Tu DN, Zou AR, Liao YH, Du YM, Wang XP, Li L., Sheng Li Xue Bao. August 25, 2008; 60 (4): 525-34.

[The persistent expression of HERG channel in Xenopus oocyte and alteration of current]., Wang XP, Li L, Zou AR, Tu DN, Liao YH., Zhongguo Ying Yong Sheng Li Xue Za Zhi. August 1, 2008; 24 (3): 329-33.

Topological mapping of the asymmetric drug binding to the human ether-à-go-go-related gene product (HERG) potassium channel by use of tandem dimers., Myokai T, Ryu S, Shimizu H, Oiki S., Mol Pharmacol. June 1, 2008; 73 (6): 1643-51.

Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243)., Xu X, Recanatini M, Roberti M, Tseng GN., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.

A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation., Klement G, Nilsson J, Arhem P, Elinder F., Biophys J. April 15, 2008; 94 (8): 3014-22.

A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator., Perry M, Sanguinetti MC., Mol Pharmacol. April 1, 2008; 73 (4): 1044-51.

Structural basis for ether-a-go-go-related gene K+ channel subtype-dependent activation by niflumic acid., Fernandez D, Sargent J, Sachse FB, Sanguinetti MC., Mol Pharmacol. April 1, 2008; 73 (4): 1159-67.

Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants., Hassel D, Scholz EP, Trano N, Friedrich O, Just S, Meder B, Weiss DL, Zitron E, Marquart S, Vogel B, Karle CA, Seemann G, Fishman MC, Katus HA, Rottbauer W., Circulation. February 19, 2008; 117 (7): 866-75.

Relationship between intracellular ice formation in oocytes of the mouse and Xenopus and the physical state of the external medium--a revisit., Mazur P, Kleinhans FW., Cryobiology. February 1, 2008; 56 (1): 22-7.

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