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Summary Expression Phenotypes Gene Literature (132) GO Terms (1) Nucleotides (120) Proteins (61) Interactants (71) Wiki
XB--977698

Papers associated with asic1



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Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels., Gupta K, Zamanian M, Bae C, Milescu M, Krepkiy D, Tilley DC, Sack JT, Yarov-Yarovoy V, Kim JI, Swartz KJ., Elife. January 6, 2015; 4 e06774.                


The comprehensive analysis of DEG/ENaC subunits in Hydra reveals a large variety of peptide-gated channels, potentially involved in neuromuscular transmission., Assmann M, Kuhn A, Dürrnagel S, Holstein TW, Gründer S., BMC Biol. October 14, 2014; 12 84.                      


Intersubunit conformational changes mediate epithelial sodium channel gating., Collier DM, Tomkovicz VR, Peterson ZJ, Benson CJ, Snyder PM., J Gen Physiol. October 1, 2014; 144 (4): 337-48.                    


Ion conduction and selectivity in acid-sensing ion channel 1., Yang L, Palmer LG., J Gen Physiol. September 1, 2014; 144 (3): 245-55.                              


Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry., Bartoi T, Augustinowski K, Polleichtner G, Gründer S, Ulbrich MH., Proc Natl Acad Sci U S A. June 3, 2014; 111 (22): 8281-6.


Protonation controls ASIC1a activity via coordinated movements in multiple domains., Bonifacio G, Lelli CI, Kellenberger S., J Gen Physiol. January 1, 2014; 143 (1): 105-18.                  


The bile acid-sensitive ion channel (BASIC) is activated by alterations of its membrane environment., Schmidt A, Lenzig P, Oslender-Bujotzek A, Kusch J, Lucas SD, Gründer S, Wiemuth D., PLoS One. January 1, 2014; 9 (10): e111549.                    


Independent contribution of extracellular proton binding sites to ASIC1a activation., Krauson AJ, Rued AC, Carattino MD., J Biol Chem. November 29, 2013; 288 (48): 34375-83.


Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation., Frey EN, Pavlovicz RE, Wegman CJ, Li C, Askwith CC., PLoS One. August 12, 2013; 8 (8): e71733.            


Gating transitions in the palm domain of ASIC1a., Della Vecchia MC, Rued AC, Carattino MD., J Biol Chem. February 22, 2013; 288 (8): 5487-95.


Impact of recovery from desensitization on acid-sensing ion channel-1a (ASIC1a) current and response to high frequency stimulation., Li T, Yang Y, Canessa CM., J Biol Chem. November 23, 2012; 287 (48): 40680-9.


Black mamba venom peptides target acid-sensing ion channels to abolish pain., Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert-Gay AS, Debayle D, Friend V, Alloui A, Lazdunski M, Lingueglia E., Nature. October 25, 2012; 490 (7421): 552-5.


Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline., Alijevic O, Kellenberger S., J Biol Chem. October 19, 2012; 287 (43): 36059-70.


High Ca(2+) permeability of a peptide-gated DEG/ENaC from Hydra., Dürrnagel S, Falkenburger BH, Gründer S., J Gen Physiol. October 1, 2012; 140 (4): 391-402.                


Lignan from thyme possesses inhibitory effect on ASIC3 channel current., Dubinnyi MA, Osmakov DI, Koshelev SG, Kozlov SA, Andreev YA, Zakaryan NA, Dyachenko IA, Bondarenko DA, Arseniev AS, Grishin EV., J Biol Chem. September 21, 2012; 287 (39): 32993-3000.


Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity., Carattino MD, Della Vecchia MC., J Biol Chem. April 13, 2012; 287 (16): 12927-34.


N-glycosylation of acid-sensing ion channel 1a regulates its trafficking and acidosis-induced spine remodeling., Jing L, Chu XP, Jiang YQ, Collier DM, Wang B, Jiang Q, Snyder PM, Zha XM., J Neurosci. March 21, 2012; 32 (12): 4080-91.


A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain., Bohlen CJ, Chesler AT, Sharif-Naeini R, Medzihradszky KF, Zhou S, King D, Sánchez EE, Burlingame AL, Basbaum AI, Julius D., Nature. November 16, 2011; 479 (7373): 410-4.      


Cross-reactivity of acid-sensing ion channel and Na⁺-H⁺ exchanger antagonists with nicotinic acetylcholine receptors., Santos-Torres J, Ślimak MA, Auer S, Ibañez-Tallon I., J Physiol. November 1, 2011; 589 (Pt 21): 5109-23.


The interaction between two extracellular linker regions controls sustained opening of acid-sensing ion channel 1., Springauf A, Bresenitz P, Gründer S., J Biol Chem. July 8, 2011; 286 (27): 24374-84.


Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death., Sherwood TW, Lee KG, Gormley MG, Askwith CC., J Neurosci. June 29, 2011; 31 (26): 9723-34.


Insights into the mechanism of pore opening of acid-sensing ion channel 1a., Tolino LA, Okumura S, Kashlan OB, Carattino MD., J Biol Chem. May 6, 2011; 286 (18): 16297-307.


Base of the thumb domain modulates epithelial sodium channel gating., Shi S, Ghosh DD, Okumura S, Carattino MD, Kashlan OB, Sheng S, Kleyman TR., J Biol Chem. April 29, 2011; 286 (17): 14753-61.


Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis., Edelheit O, Hanukoglu I, Dascal N, Hanukoglu A., Am J Physiol Renal Physiol. April 1, 2011; 300 (4): F887-97.


Asp433 in the closing gate of ASIC1 determines stability of the open state without changing properties of the selectivity filter or Ca2+ block., Li T, Yang Y, Canessa CM., J Gen Physiol. March 1, 2011; 137 (3): 289-97.            


Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1., Li T, Yang Y, Canessa CM., Nat Commun. January 1, 2011; 2 399.


Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant., Hoagland EN, Sherwood TW, Lee KG, Walker CJ, Askwith CC., J Biol Chem. December 31, 2010; 285 (53): 41852-62.


Asn415 in the beta11-beta12 linker decreases proton-dependent desensitization of ASIC1., Li T, Yang Y, Canessa CM., J Biol Chem. October 8, 2010; 285 (41): 31285-91.


Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase., Clark EB, Jovov B, Rooj AK, Fuller CM, Benos DJ., J Biol Chem. August 27, 2010; 285 (35): 27130-43.


Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation., Li T, Yang Y, Canessa CM., J Biol Chem. July 16, 2010; 285 (29): 22706-12.


Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel., Li T, Yang Y, Canessa CM., Am J Physiol Cell Physiol. July 1, 2010; 299 (1): C66-73.


Diarylamidines: high potency inhibitors of acid-sensing ion channels., Chen X, Qiu L, Li M, Dürrnagel S, Orser BA, Xiong ZG, MacDonald JF., Neuropharmacology. June 1, 2010; 58 (7): 1045-53.


The contact region between three domains of the extracellular loop of ASIC1a is critical for channel function., Bargeton B, Kellenberger S., J Biol Chem. April 30, 2010; 285 (18): 13816-26.


The Drosophila gene CheB42a is a novel modifier of Deg/ENaC channel function., Ben-Shahar Y, Lu B, Collier DM, Snyder PM, Schnizler M, Welsh MJ., PLoS One. February 2, 2010; 5 (2): e9395.              


Conformational changes associated with proton-dependent gating of ASIC1a., Passero CJ, Okumura S, Carattino MD., J Biol Chem. December 25, 2009; 284 (52): 36473-36481.


Structural elements for the generation of sustained currents by the acid pain sensor ASIC3., Salinas M, Lazdunski M, Lingueglia E., J Biol Chem. November 13, 2009; 284 (46): 31851-9.


Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death., Sherwood TW, Askwith CC., J Neurosci. November 11, 2009; 29 (45): 14371-80.


Insights into the molecular determinants of proton inhibition in an acid-inactivated degenerins and mammalian epithelial Na(+) channel., Wang Y, Bianchi L., Biochemistry. October 27, 2009; 48 (42): 10005-13.


Extracellular chloride regulates the epithelial sodium channel., Collier DM, Snyder PM., J Biol Chem. October 23, 2009; 284 (43): 29320-5.


Identification of protein domains that control proton and calcium sensitivity of ASIC1a., Sherwood T, Franke R, Conneely S, Joyner J, Arumugan P, Askwith C., J Biol Chem. October 9, 2009; 284 (41): 27899-907.


Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits., Zha XM, Wang R, Collier DM, Snyder PM, Wemmie JA, Welsh MJ., Proc Natl Acad Sci U S A. March 3, 2009; 106 (9): 3573-8.


Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels., Li T, Yang Y, Canessa CM., J Biol Chem. February 13, 2009; 284 (7): 4689-94.          


Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function., Bashari E, Qadri YJ, Zhou ZH, Kapoor N, Anderson SJ, Meltzer RH, Fuller CM, Benos DJ., Am J Physiol Cell Physiol. February 1, 2009; 296 (2): C372-84.


Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b., Kadurin I, Golubovic A, Leisle L, Schindelin H, Gründer S., Biochem J. June 15, 2008; 412 (3): 469-75.


Endogenous arginine-phenylalanine-amide-related peptides alter steady-state desensitization of ASIC1a., Sherwood TW, Askwith CC., J Biol Chem. January 25, 2008; 283 (4): 1818-30.


Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a., Paukert M, Chen X, Polleichtner G, Schindelin H, Gründer S., J Biol Chem. January 4, 2008; 283 (1): 572-581.


Nafamostat mesilate reversibly blocks acid-sensing ion channel currents., Ugawa S, Ishida Y, Ueda T, Inoue K, Nagao M, Shimada S., Biochem Biophys Res Commun. November 9, 2007; 363 (1): 203-8.


Zebrafish acid-sensing ion channel (ASIC) 4, characterization of homo- and heteromeric channels, and identification of regions important for activation by H+., Chen X, Polleichtner G, Kadurin I, Gründer S., J Biol Chem. October 19, 2007; 282 (42): 30406-13.


Permeating protons contribute to tachyphylaxis of the acid-sensing ion channel (ASIC) 1a., Chen X, Gründer S., J Physiol. March 15, 2007; 579 (Pt 3): 657-70.


Strong modulation by RFamide neuropeptides of the ASIC1b/3 heteromer in competition with extracellular calcium., Chen X, Paukert M, Kadurin I, Pusch M, Gründer S., Neuropharmacology. June 1, 2006; 50 (8): 964-74.

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