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Summary Expression Phenotypes Gene Literature (134) GO Terms (21) Nucleotides (172) Proteins (52) Interactants (310) Wiki
XB--985622

Papers associated with dtl



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The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus., Griffin JN, Sondalle SB, Del Viso F, Baserga SJ, Khokha MK., PLoS Genet. March 10, 2015; 11 (3): e1005018.                              

A novel PKD2L1 C-terminal domain critical for trimerization and channel function., Zheng W, Hussein S, Yang J, Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y, Cao Y, Zeng H, Tang J, Chen XZ., Sci Rep. January 12, 2015; 5 9460.              

Activation of TRESK channels by the inflammatory mediator lysophosphatidic acid balances nociceptive signalling., Kollert S, Dombert B, Döring F, Wischmeyer E., Sci Rep. January 12, 2015; 5 12548.            

Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca(2.)., Hussein S, Zheng W, Dyte C, Wang Q, Yang J, Zhang F, Tang J, Cao Y, Cao Y, Chen XZ., Sci Rep. January 12, 2015; 5 15752.                  

Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels., Chang HK, Iwamoto M, Oiki S, Shieh RC., Sci Rep. January 12, 2015; 5 18404.              

Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries., Bagriantsev SN, Chatelain FC, Clark KA, Alagem N, Reuveny E, Minor DL., ACS Chem Neurosci. September 17, 2014; 5 (9): 812-22.              

Intracellular ATP does not inhibit Slo2.1 K+ channels., Garg P, Sanguinetti MC., Physiol Rep. September 11, 2014; 2 (9):         

Ion conduction and selectivity in acid-sensing ion channel 1., Yang L, Palmer LG., J Gen Physiol. September 1, 2014; 144 (3): 245-55.                              

Thymine DNA glycosylase is a CRL4Cdt2 substrate., Slenn TJ, Morris B, Havens CG, Freeman RM, Takahashi TS, Walter JC., J Biol Chem. August 15, 2014; 289 (33): 23043-23055.

Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR., Cui G, Rahman KS, Infield DT, Kuang C, Prince CZ, McCarty NA., J Gen Physiol. August 1, 2014; 144 (2): 159-79.                          

Biomechanics and the thermotolerance of development., von Dassow M, Miller CJ, Davidson LA., PLoS One. January 1, 2014; 9 (4): e95670.            

2-Aminoethoxydiphenyl borate activates the mechanically gated human KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK), and KCNK 10 (TREK-2)., Beltrán L, Beltrán M, Aguado A, Gisselmann G, Hatt H., Front Pharmacol. May 15, 2013; 4 63.      

Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation., Zhu XN, Kim DH, Lin HR, Budhavarapu VN, Rosenbaum HB, Mueller PR, Yew PR., Cell Div. April 22, 2013; 8 (1): 5.              

Molecular mechanism of voltage sensing in voltage-gated proton channels., Gonzalez C, Rebolledo S, Perez ME, Larsson HP., J Gen Physiol. March 1, 2013; 141 (3): 275-85.              

The eag domain regulates hERG channel inactivation gating via a direct interaction., Gustina AS, Trudeau MC., J Gen Physiol. February 1, 2013; 141 (2): 229-41.                  

The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK., Beltrán LR, Dawid C, Beltrán M, Gisselmann G, Degenhardt K, Mathie K, Hofmann T, Hatt H., Front Pharmacol. January 1, 2013; 4 141.              

Cargo transport by cytoplasmic Dynein can center embryonic centrosomes., Longoria RA, Shubeita GT., PLoS One. January 1, 2013; 8 (7): e67710.            

Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains., Bagriantsev SN, Clark KA, Minor DL., EMBO J. August 1, 2012; 31 (15): 3297-308.            

Inhibition of voltage-gated Na(+) currents in sensory neurones by the sea anemone toxin APETx2., Blanchard MG, Rash LD, Kellenberger S., Br J Pharmacol. April 1, 2012; 165 (7): 2167-77.

Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2., Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC., J Biol Chem. March 30, 2012; 287 (14): 11410-21.

Infrared light excites cells by changing their electrical capacitance., Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F., Nat Commun. March 13, 2012; 3 736.          

Covalent modification of mutant rat P2X2 receptors with a thiol-reactive fluorophore allows channel activation by zinc or acidic pH without ATP., Dellal SS, Hume RI., PLoS One. January 1, 2012; 7 (10): e47147.                    

Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytes., Maksaev G, Haswell ES., J Gen Physiol. December 1, 2011; 138 (6): 641-9.        

Molecular dynamics simulations of the Cx26 hemichannel: evaluation of structural models with Brownian dynamics., Kwon T, Harris AL, Rossi A, Bargiello TA., J Gen Physiol. November 1, 2011; 138 (5): 475-93.            

A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction., Raman M, Havens CG, Walter JC, Harper JW., Mol Cell. October 7, 2011; 44 (1): 72-84.

5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals., McKinnon NK, Reeves DC, Akabas MH., J Gen Physiol. October 1, 2011; 138 (4): 453-66.                

TRPM7 is required within zebrafish sensory neurons for the activation of touch-evoked escape behaviors., Low SE, Amburgey K, Horstick E, Linsley J, Sprague SM, Cui WW, Zhou W, Hirata H, Saint-Amant L, Hume RI, Kuwada JY., J Neurosci. August 10, 2011; 31 (32): 11633-44.                  

Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase., Havens CG, Walter JC., Genes Dev. August 1, 2011; 25 (15): 1568-82.

Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4(Cdt2) -mediated proteolysis., Michishita M, Morimoto A, Ishii T, Komori H, Shiomi Y, Higuchi Y, Nishitani H., Genes Cells. January 1, 2011; 16 (1): 12-22.        

A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons., Park JY, Remy S, Varela J, Cooper DC, Chung S, Kang HW, Lee JH, Spruston N., PLoS Biol. November 16, 2010; 8 (11): e1000534.                    

CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase., Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC, Zou L., Mol Cell. October 8, 2010; 40 (1): 22-33.

The CRL4Cdt2 ubiquitin ligase mediates the proteolysis of cyclin-dependent kinase inhibitor Xic1 through a direct association with PCNA., Kim DH, Budhavarapu VN, Herrera CR, Nam HW, Kim YS, Yew PR., Mol Cell Biol. September 1, 2010; 30 (17): 4120-33.

Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other., Ambrosi C, Gassmann O, Pranskevich JN, Boassa D, Smock A, Wang J, Dahl G, Steinem C, Sosinsky GE., J Biol Chem. August 6, 2010; 285 (32): 24420-31.                    

Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome., Sánchez HA, Mese G, Srinivas M, White TW, Verselis VK., J Gen Physiol. July 1, 2010; 136 (1): 47-62.                  

An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors., Stürzebecher AS, Hu J, Smith ES, Frahm S, Santos-Torres J, Kampfrath B, Auer S, Lewin GR, Ibañez-Tallon I., J Physiol. May 15, 2010; 588 (Pt 10): 1695-707.        

The N terminus of monoamine transporters is a lever required for the action of amphetamines., Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH., J Biol Chem. April 2, 2010; 285 (14): 10924-38.                      

Activation of Slo2.1 channels by niflumic acid., Dai L, Garg V, Sanguinetti MC., J Gen Physiol. March 1, 2010; 135 (3): 275-95.                                

Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics., Larsen AP, Olesen SP., PLoS One. February 2, 2010; 5 (2): e9021.            

Functional characterization of intracellular Dictyostelium discoideum P2X receptors., Ludlow MJ, Durai L, Ennion SJ., J Biol Chem. December 11, 2009; 284 (50): 35227-39.                

The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line., Swayne LA, Mezghrani A, Varrault A, Chemin J, Bertrand G, Dalle S, Bourinet E, Lory P, Miller RJ, Nargeot J, Monteil A., EMBO Rep. August 1, 2009; 10 (8): 873-80.        

Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels., Nagatomo K, Kubo Y., Proc Natl Acad Sci U S A. November 11, 2008; 105 (45): 17373-8.    

Divalent cations regulate connexin hemichannels by modulating intrinsic voltage-dependent gating., Verselis VK, Srinivas M., J Gen Physiol. September 1, 2008; 132 (3): 315-27.            

Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition., Chan KW, Wheeler A, Csanády L., J Gen Physiol. January 1, 2008; 131 (1): 43-58.                    

Charge scan reveals an extended region at the intracellular end of the GABA receptor pore that can influence ion selectivity., Wotring VE, Weiss DS., J Gen Physiol. January 1, 2008; 131 (1): 87-97.              

Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.                                                                        

A combined patch-clamp and electrorotation study of the voltage- and frequency-dependent membrane capacitance caused by structurally dissimilar lipophilic anions., Zimmermann D, Kiesel M, Terpitz U, Zhou A, Reuss R, Kraus J, Schenk WA, Bamberg E, Sukhorukov VL., J Membr Biol. January 1, 2008; 221 (2): 107-21.            

State-dependent block of BK channels by synthesized shaker ball peptides., Li W, Aldrich RW., J Gen Physiol. October 1, 2006; 128 (4): 423-41.                        

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1., Jin J, Arias EE, Chen J, Harper JW, Walter JC., Mol Cell. September 1, 2006; 23 (5): 709-21.

Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channels., Xie LH, John SA, Ribalet B, Weiss JN., J Gen Physiol. December 1, 2005; 126 (6): 541-9.              

Sensitization and translocation of TRPV1 by insulin and IGF-I., Van Buren JJ, Bhat S, Rotello R, Pauza ME, Premkumar LS., Mol Pain. April 27, 2005; 1 17.        

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