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Summary Expression Phenotypes Gene Literature (31) GO Terms (7) Nucleotides (294) Proteins (51) Interactants (354) Wiki
XB--478638

Papers associated with dact1



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Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation., Cheyette BN, Waxman JS, Miller JR, Takemaru K, Sheldahl LC, Khlebtsova N, Fox EP, Earnest T, Moon RT., Dev Cell. April 1, 2002; 2 (4): 449-61.  

Frodo interacts with Dishevelled to transduce Wnt signals., Gloy J, Hikasa H, Sokol SY., Nat Cell Biol. May 1, 2002; 4 (5): 351-7.

Identification and characterization of human DAPPER1 and DAPPER2 genes in silico., Katoh M, Katoh M., Int J Oncol. April 1, 2003; 22 (4): 907-13.

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled., Wong HC, Bourdelas A, Krauss A, Lee HJ, Shao Y, Wu D, Mlodzik M, Shi DL, Zheng J., Mol Cell. November 1, 2003; 12 (5): 1251-60.

Two Frodo/Dapper homologs are expressed in the developing brain and mesoderm of zebrafish., Gillhouse M, Wagner Nyholm M, Hikasa H, Sokol SY, Grinblat Y., Dev Dyn. July 1, 2004; 230 (3): 403-9.

The involvement of Frodo in TCF-dependent signaling and neural tissue development., Hikasa H, Sokol SY., Development. October 1, 2004; 131 (19): 4725-34.      

Zebrafish Dapper1 and Dapper2 play distinct roles in Wnt-mediated developmental processes., Waxman JS, Hocking AM, Stoick CL, Moon RT., Development. December 1, 2004; 131 (23): 5909-21.

HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing., Yau TO, Chan CY, Chan KL, Lee MF, Wong CM, Fan ST, Ng IO., Oncogene. February 24, 2005; 24 (9): 1607-14.

A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required for heart development., Brott BK, Sokol SY., Dev Cell. May 1, 2005; 8 (5): 703-15.  

Identification and characterization of rat Dact1 and Dact2 genes in silico., Katoh M., Int J Mol Med. June 1, 2005; 15 (6): 1045-9.

Frodo proteins: modulators of Wnt signaling in vertebrate development., Brott BK, Sokol SY., Differentiation. September 1, 2005; 73 (7): 323-9.      

Vertebrate homologues of Frodo are dynamically expressed during embryonic development in tissues undergoing extensive morphogenetic movements., Hunter NL, Hikasa H, Dymecki SM, Sokol SY., Dev Dyn. January 1, 2006; 235 (1): 279-84.  

Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation., Zhang L, Gao X, Wen J, Ning Y, Chen YG., J Biol Chem. March 31, 2006; 281 (13): 8607-12.

Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals., Park JI, Ji H, Jun S, Gu D, Hikasa H, Li L, Sokol SY, McCrea PD., Dev Cell. November 1, 2006; 11 (5): 683-95.

The evolutionally conserved activity of Dapper2 in antagonizing TGF-beta signaling., Su Y, Zhang L, Gao X, Meng F, Wen J, Zhou H, Meng A, Chen YG., FASEB J. March 1, 2007; 21 (3): 682-90.

Dpr Acts as a molecular switch, inhibiting Wnt signaling when unphosphorylated, but promoting Wnt signaling when phosphorylated by casein kinase Idelta/epsilon., Teran E, Branscomb AD, Seeling JM., PLoS One. January 1, 2009; 4 (5): e5522.          

Use of adenovirus for ectopic gene expression in Xenopus: Chicken dapper genes are versatile markers for mesodermal tissues, embryonic muscle stem cells, neural crest cells, and neurogenic placodes., Alvares LE, Winterbottom FL, Sobreira DR, Xavier-Neto J, Schubert FR, Dietrich S., Dev Dyn. July 1, 2009; 238 (7): spcone.

Downregulation of HDPR1 is associated with poor prognosis and affects expression levels of p120-catenin and beta-catenin in nonsmall cell lung cancer., Yang ZQ, Zhao Y, Liu Y, Zhang JY, Zhang S, Jiang GY, Zhang PX, Yang LH, Liu D, Li QC, Wang EH., Mol Carcinog. May 1, 2010; 49 (5): 508-19.

Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer., Jia Y, Yang Y, Brock MV, Zhan Q, Herman JG, Guo M., J Pathol. June 1, 2013; 230 (2): 194-204.

Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers., Plouhinec JL, Roche DD, Pegoraro C, Figueiredo AL, Maczkowiak F, Brunet LJ, Milet C, Vert JP, Pollet N, Harland RM, Monsoro-Burq AH., Dev Biol. February 15, 2014; 386 (2): 461-72.                                            

Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways., Lee HJ, Shi DL, Zheng JJ., Elife. August 22, 2015; 4 e08142.                      

Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2., Rabadán MA, Herrera A, Fanlo L, Usieto S, Carmona-Fontaine C, Barriga EH, Mayor R, Pons S, Martí E., Development. June 15, 2016; 143 (12): 2194-205.          

Heterozygous Pathogenic Variant in DACT1 Causes an Autosomal-Dominant Syndrome with Features Overlapping Townes-Brocks Syndrome., Webb BD, Metikala S, Wheeler PG, Sherpa MD, Houten SM, Horb ME, Schadt EE., Hum Mutat. April 1, 2017; 38 (4): 373-377.

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        

Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1., Lee H, Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK., Development. April 10, 2018; 145 (7):               

RARγ is required for mesodermal gene expression prior to gastrulation in Xenopus., Janesick A, Tang W, Shioda T, Blumberg B., Development. September 17, 2018; 145 (18):                           

Dact-4 is a Xenopus laevis Spemann organizer gene related to the Dapper/Frodo antagonist of β-catenin family of proteins., Colozza G, De Robertis EM., Gene Expr Patterns. December 1, 2020; 38 119153.                        

Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis., Edwards-Faret G, González-Pinto K, Cebrián-Silla A, Peñailillo J, García-Verdugo JM, Larraín J., Neural Dev. February 2, 2021; 16 (1): 2.                              

Fibroblast dedifferentiation as a determinant of successful regeneration., Lin TY, Gerber T, Taniguchi-Sugiura Y, Murawala P, Hermann S, Grosser L, Shibata E, Treutlein B, Tanaka EM., Dev Cell. May 17, 2021; 56 (10): 1541-1551.e6.                    

Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis., Wu HY, Zhou YM, Liao ZQ, Zhong JW, Liu YB, Zhao H, Liang CQ, Huang RJ, Park KS, Feng SS, Zheng L, Cai DQ, Qi XF., NPJ Regen Med. June 29, 2021; 6 (1): 36.                    

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