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Summary Expression Phenotypes Gene Literature (47) GO Terms (9) Nucleotides (337) Proteins (36) Interactants (553) Wiki
XB-GENEPAGE-478821

Papers associated with map2k1



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3 paper(s) referencing morpholinos

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Injury-induced Erk1/2 signaling tissue-specifically interacts with Ca2+ activity and is necessary for regeneration of spinal cord and skeletal muscle., Levin JB, Borodinsky LN., Cell Calcium. January 1, 2022; 102 102540.                                  


Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning., Reis AH, Sokol SY., Development. January 1, 2020; 147 (10):                   


Predation threats for a 24-h period activated the extension of axons in the brains of Xenopus tadpoles., Mori T, Kitani Y, Hatakeyama D, Machida K, Goto-Inoue N, Hayakawa S, Yamamoto N, Kashiwagi K, Kashiwagi A., Sci Rep. January 1, 2020; 10 (1): 11737.                    


Opposite T3 Response of ACTG1-FOS Subnetwork Differentiate Tailfin Fate in Xenopus Tadpole and Post-hatching Axolotl., Kerdivel G, Blugeon C, Fund C, Rigolet M, Sachs LM, Buisine N., Front Endocrinol (Lausanne). January 1, 2019; 10 194.              


A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway., Popov IK, Hiatt SM, Whalen S, Keren B, Ruivenkamp C, van Haeringen A, Chen MJ, Cooper GM, Korf BR, Chang C., Front Physiol. January 1, 2019; 10 388.                                


NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects., Sequerra EB, Goyal R, Castro PA, Levin JB, Borodinsky LN., J Neurosci. January 1, 2018; 38 (20): 4762-4773.          


Xenopus SOX5 enhances myogenic transcription indirectly through transrepression., Della Gaspera B, Chesneau A, Weill L, Charbonnier F, Chanoine C., Dev Biol. January 1, 2018; 442 (2): 262-275.                    


Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development., Peuchen EH, Cox OF, Sun L, Hebert AS, Coon JJ, Champion MM, Dovichi NJ, Huber PW., Sci Rep. November 15, 2017; 7 (1): 15647.                          


Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2., Scerbo P, Marchal L, Kodjabachian L., Elife. January 1, 2017; 6                               


The Nuclear Proteome of a Vertebrate., Wühr M, Güttler T, Peshkin L, McAlister GC, Sonnett M, Ishihara K, Groen AC, Presler M, Erickson BK, Mitchison TJ, Kirschner MW, Gygi SP., Curr Biol. October 19, 2015; 25 (20): 2663-71.        


Novel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms., Sipieter F, Cappe B, Gonzalez Pisfil M, Spriet C, Bodart JF, Cailliau-Maggio K, Vandenabeele P, Héliot L, Riquet FB., PLoS One. January 1, 2015; 10 (10): e0140924.          


A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis., Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G., Cell. November 6, 2014; 159 (4): 844-56.              


Acute synthesis of CPEB is required for plasticity of visual avoidance behavior in Xenopus., Shen W, Liu HH, Schiapparelli L, McClatchy D, He HY, Yates JR, Cline HT., Cell Rep. February 27, 2014; 6 (4): 737-47.


Mammalian tribbles homologs at the crossroads of endoplasmic reticulum stress and Mammalian target of rapamycin pathways., Cunard R., Scientifica (Cairo). January 1, 2013; 2013 750871.    


Coregulation of multiple signaling mechanisms in pp60v-Src-induced closure of Cx43 gap junction channels., Mitra SS, Xu J, Nicholson BJ., J Membr Biol. August 1, 2012; 245 (8): 495-506.


TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: a new link in the FGF/BMP regulatory network., Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK., Differentiation. April 1, 2012; 83 (4): 210-9.                  


Systematic discovery of nonobvious human disease models through orthologous phenotypes., McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM., Proc Natl Acad Sci U S A. April 6, 2010; 107 (14): 6544-9.                                    


MAPK pathway activation delays G2/M progression by destabilizing Cdc25B., Astuti P, Pike T, Widberg C, Payne E, Harding A, Hancock J, Gabrielli B., J Biol Chem. December 4, 2009; 284 (49): 33781-8.


Activation of extracellular signal-regulated kinases during dehydration in the African clawed frog, Xenopus laevis., Malik AI, Storey KB., J Exp Biol. August 1, 2009; 212 (Pt 16): 2595-603.


Antibody microarray analyses of signal transduction protein expression and phosphorylation during porcine oocyte maturation., Pelech S, Jelinkova L, Susor A, Zhang H, Shi X, Pavlok A, Kubelka M, Kovarova H., J Proteome Res. July 1, 2008; 7 (7): 2860-71.


A comparison of Hsp90alpha and Hsp90beta interactions with cochaperones and substrates., Taherian A, Krone PH, Ovsenek N., Biochem Cell Biol. February 1, 2008; 86 (1): 37-45.


Hes6 is required for MyoD induction during gastrulation., Murai K, Vernon AE, Philpott A, Jones P., Dev Biol. December 1, 2007; 312 (1): 61-76.            


Transgenic Xenopus with prx1 limb enhancer reveals crucial contribution of MEK/ERK and PI3K/AKT pathways in blastema formation during limb regeneration., Suzuki M, Satoh A, Ide H, Tamura K, Tamura K., Dev Biol. April 15, 2007; 304 (2): 675-86.              


Paxillin regulates steroid-triggered meiotic resumption in oocytes by enhancing an all-or-none positive feedback kinase loop., Rasar M, DeFranco DB, Hammes SR., J Biol Chem. December 22, 2006; 281 (51): 39455-64.              


Metaphase arrest by cyclin E-Cdk2 requires the spindle-checkpoint kinase Mps1., Grimison B, Liu J, Lewellyn AL, Maller JL., Curr Biol. October 10, 2006; 16 (19): 1968-73.


Mechanistic studies of the mitotic activation of Mos., Yue J, Ferrell JE., Mol Cell Biol. July 1, 2006; 26 (14): 5300-9.              


B-Raf and C-Raf are required for Ras-stimulated p42 MAP kinase activation in Xenopus egg extracts., Yue J, Xiong W, Ferrell JE., Oncogene. June 1, 2006; 25 (23): 3307-15.


Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field., Rajnicek AM, Foubister LE, McCaig CD., J Cell Sci. May 1, 2006; 119 (Pt 9): 1723-35.


Differential roles of p39Mos-Xp42Mpk1 cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes., Bodart JF, Baert FY, Sellier C, Duesbery NS, Flament S, Vilain JP., Dev Biol. July 15, 2005; 283 (2): 373-83.


Expression of Xenopus suppressor of cytokine signaling 3 (xSOCS3) is induced by epithelial wounding., Kuliyev E, Doherty JR, Mead PE., Dev Dyn. July 1, 2005; 233 (3): 1123-30.      


FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation., Sivak JM, Petersen LF, Amaya E., Dev Cell. May 1, 2005; 8 (5): 689-701.      


Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells., Silverman E, Frödin M, Gammeltoft S, Maller JL., Mol Cell Biol. December 1, 2004; 24 (24): 10573-83.


Mos mediates the mitotic activation of p42 MAPK in Xenopus egg extracts., Yue J, Ferrell JE., Curr Biol. September 7, 2004; 14 (17): 1581-6.


ATM/ATR-independent inhibition of cyclin B accumulation in response to hydroxyurea in nontransformed cell lines is altered in tumour cell lines., Florensa R, Bachs O, Agell N., Oncogene. November 13, 2003; 22 (51): 8283-92.


Mek2 is dispensable for mouse growth and development., Bélanger LF, Roy S, Tremblay M, Brott B, Steff AM, Mourad W, Hugo P, Erikson R, Charron J., Mol Cell Biol. July 1, 2003; 23 (14): 4778-87.


Mechanism of mitosis-specific activation of MEK1., Harding A, Giles N, Burgess A, Hancock JF, Gabrielli BG., J Biol Chem. May 9, 2003; 278 (19): 16747-54.


Anthrax lethal factor proteolysis and inactivation of MAPK kinase., Chopra AP, Boone SA, Liang X, Duesbery NS., J Biol Chem. March 14, 2003; 278 (11): 9402-6.


Signalling pathways in oocyte meiotic maturation., Schmitt A, Nebreda AR., J Cell Sci. June 15, 2002; 115 (Pt 12): 2457-9.  


MAP kinase converts MyoD into an instructive muscle differentiation factor in Xenopus., Zetser A, Frank D, Bengal E., Dev Biol. December 1, 2001; 240 (1): 168-81.                


The polo-like kinase Plx1 is required for activation of the phosphatase Cdc25C and cyclin B-Cdc2 in Xenopus oocytes., Qian YW, Erikson E, Taieb FE, Maller JL., Mol Biol Cell. June 1, 2001; 12 (6): 1791-9.


Bub1 is activated by the protein kinase p90(Rsk) during Xenopus oocyte maturation., Schwab MS, Roberts BT, Gross SD, Tunquist BJ, Taieb FE, Lewellyn AL, Maller JL., Curr Biol. February 6, 2001; 11 (3): 141-50.  


Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta., Giroux S, Tremblay M, Bernard D, Cardin-Girard JF, Aubry S, Larouche L, Rousseau S, Huot J, Landry J, Jeannotte L, Charron J., Curr Biol. April 8, 1999; 9 (7): 369-72.


The 96 kDa protein kinase activated by oncogenic Ras in Xenopus egg extracts is also activated by constitutively active Mek: activation requires serine/threonine phosphorylation., Pan BT, Zhang Y, Brott B, Chen DH., Oncogene. April 10, 1997; 14 (14): 1653-60.


KSR modulates signal propagation within the MAPK cascade., Therrien M, Michaud NR, Rubin GM, Morrison DK., Genes Dev. November 1, 1996; 10 (21): 2684-95.


Biochemical and biological analysis of Mek1 phosphorylation site mutants., Huang W, Kessler DS, Erikson RL., Mol Biol Cell. March 1, 1995; 6 (3): 237-45.


MAP kinase-dependent pathways in cell cycle control., Pelech SL, Charest DL., Prog Cell Cycle Res. January 1, 1995; 1 33-52.


Molecular cloning and sequencing of a carp cDNA encoding mitogen-activated protein kinase kinase., Huang CJ, Lee MS, Chang GD, Huang FL, Lo TB., Biochim Biophys Acta. January 13, 1994; 1220 (2): 223-5.

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