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Genetically programmed retinoic acid deficiency during gastrulation phenocopies most known developmental defects due to acute prenatal alcohol exposure in FASD. , Petrelli B, Oztürk A, Pind M, Ayele H, Fainsod A , Hicks GG., Front Cell Dev Biol. January 1, 2023; 11 1208279.
Alcohol induces neural tube defects by reducing retinoic acid signaling and promoting neural plate expansion. , Edri T, Cohen D, Shabtai Y, Fainsod A ., Front Cell Dev Biol. January 1, 2023; 11 1282273.
Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly. , Gur M, Bendelac-Kapon L, Shabtai Y, Pillemer G, Fainsod A ., Front Cell Dev Biol. January 1, 2022; 10 844619.
Acetaldehyde inhibits retinoic acid biosynthesis to mediate alcohol teratogenicity. , Shabtai Y, Bendelac L, Jubran H, Hirschberg J, Fainsod A ., Sci Rep. January 10, 2018; 8 (1): 347.
RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM(®) genes for hereditary disorders of hearing and balance. , Ramírez-Gordillo D, Powers TR , van Velkinburgh JC, Trujillo-Provencio C, Schilkey F, Serrano EE ., BMC Res Notes. November 18, 2015; 8 691.