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Summary Expression Phenotypes Gene Literature (29) GO Terms (26) Nucleotides (193) Proteins (53) Interactants (408) Wiki
XB-GENEPAGE-481306

Papers associated with smad6



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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor., Hata A, Lagna G, Massagué J, Hemmati-Brivanlou A., Genes Dev. January 15, 1998; 12 (2): 186-97.          

Smad6 functions as an intracellular antagonist of some TGF-beta family members during Xenopus embryogenesis., Nakayama T, Gardner H, Berg LK, Christian JL., Genes Cells. June 1, 1998; 3 (6): 387-94.                

Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer., Casellas R, Brivanlou AH., Dev Biol. June 1, 1998; 198 (1): 1-12.                

A molecular basis for Smad specificity., Lagna G, Hemmati-Brivanlou A., Dev Dyn. March 1, 1999; 214 (3): 269-77.

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals., Christian JL, Nakayama T., Bioessays. May 1, 1999; 21 (5): 382-90.

Evidence for a role of Smad6 in chick cardiac development., Yamada M, Szendro PI, Prokscha A, Schwartz RJ, Eichele G., Dev Biol. November 1, 1999; 215 (1): 48-61.

The Xvex-1 antimorph reveals the temporal competence for organizer formation and an early role for ventral homeobox genes., Shapira E, Marom1 K, Levy V, Yelin R, Fainsod A., Mech Dev. January 1, 2000; 90 (1): 77-87.

Bone morphogenetic protein function is required for terminal differentiation of the heart but not for early expression of cardiac marker genes., Walters MJ, Wayman GA, Christian JL., Mech Dev. February 1, 2001; 100 (2): 263-73.

Dissection of inhibitory Smad proteins: both N- and C-terminal domains are necessary for full activities of Xenopus Smad6 and Smad7., Nakayama T, Berg LK, Christian JL., Mech Dev. February 1, 2001; 100 (2): 251-62.

Human truncated Smad 6 (Smad 6s) inhibits the BMP pathway in Xenopus laevis., Krishnan P, King MW, King MW, Neff AW, Sandusky GE, Bierman KL, Grinnell B, Smith RC., Dev Growth Differ. April 1, 2001; 43 (2): 115-32.

TGF-beta signalling pathways in early Xenopus development., Hill CS., Curr Opin Genet Dev. October 1, 2001; 11 (5): 533-40.    

Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling., Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K., J Biol Chem. July 23, 2004; 279 (30): 31568-74.

A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways., Zuzarte-Luís V, Montero JA, Rodriguez-León J, Merino R, Rodríguez-Rey JC, Hurlé JM., Dev Biol. August 1, 2004; 272 (1): 39-52.

Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition., Delaune E, Lemaire P, Kodjabachian L., Development. January 1, 2005; 132 (2): 299-310.                    

Temporal analysis of the early BMP functions identifies distinct anti-organizer and mesoderm patterning phases., Marom K, Levy V, Pillemer G, Fainsod A., Dev Biol. June 15, 2005; 282 (2): 442-54.              

An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling., Oren T, Torregroza I, Evans T., Nucleic Acids Res. August 1, 2005; 33 (13): 4357-67.              

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

The secreted EGF-Discoidin factor xDel1 is essential for dorsal development of the Xenopus embryo., Arakawa A, Matsuo-Takasaki M, Takai A, Inomata H, Matsumura M, Ikeya M, Takahashi K, Miyachi Y, Sasai N, Sasai Y., Dev Biol. June 1, 2007; 306 (1): 160-9.                    

Unexpected activities of Smad7 in Xenopus mesodermal and neural induction., de Almeida I, Rolo A, Batut J, Hill C, Stern CD, Linker C., Mech Dev. January 1, 2008; 125 (5-6): 421-31.              

Expression cloning of Xenopus zygote arrest 2 (Xzar2) as a novel epidermalization-promoting factor in early embryos of Xenopus laevis., Nakajima Y, Okamoto H, Kubo T, Kubo T., Genes Cells. May 1, 2009; 14 (5): 583-95.                    

Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development., Paulsen M, Legewie S, Eils R, Karaulanov E, Niehrs C., Proc Natl Acad Sci U S A. June 21, 2011; 108 (25): 10202-7.      

Role of BMP, FGF, calcium signaling, and Zic proteins in vertebrate neuroectodermal differentiation., Aruga J, Mikoshiba K., Neurochem Res. July 1, 2011; 36 (7): 1286-92.      

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling., Herhaus L, Al-Salihi MA, Dingwell KS, Cummins TD, Wasmus L, Vogt J, Ewan R, Bruce D, Macartney T, Weidlich S, Smith JC, Sapkota GP., Open Biol. May 1, 2014; 4 (5): 140065.              

Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints., Genikhovich G, Fried P, Prünster MM, Schinko JB, Gilles AF, Fredman D, Meier K, Iber D, Technau U., Cell Rep. March 17, 2015; 10 (10): 1646-1654.            

Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos., Naert T, Tulkens D, Edwards NA, Carron M, Shaidani NI, Wlizla M, Boel A, Demuynck S, Horb ME, Coucke P, Willaert A, Zorn AM, Vleminckx K, Vleminckx K., Sci Rep. September 4, 2020; 10 (1): 14662.                      

Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly., Gur M, Bendelac-Kapon L, Shabtai Y, Pillemer G, Fainsod A., Front Cell Dev Biol. January 1, 2022; 10 844619.                        

HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs., Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q, Xi Q., Cell Rep. July 12, 2022; 40 (2): 111038.                              

Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas., Zhong G, Ahimaz P, Edwards NA, Hagen JJ, Faure C, Lu Q, Kingma P, Middlesworth W, Khlevner J, El Fiky M, Schindel D, Fialkowski E, Kashyap A, Forlenza S, Kenny AP, Zorn AM, Shen Y, Chung WK., HGG Adv. July 14, 2022; 3 (3): 100107.        

Patterning of the Vertebrate Head in Time and Space by BMP Signaling., Zhu K, Spaink HP, Durston AJ., J Dev Biol. July 3, 2023; 11 (3):         

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