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Summary Expression Phenotypes Gene Literature (197) GO Terms (5) Nucleotides (130) Proteins (44) Interactants (1264) Wiki
XB--481643

Papers associated with dkk1



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R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H, Camuto CM, Niehrs C., Nat Commun. February 2, 2024; 15 (1): 1003.                                                                  

In vitro modeling of cranial placode differentiation: Recent advances, challenges, and perspectives., Griffin C, Saint-Jeannet JP., Dev Biol. February 1, 2024; 506 20-30.

The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking., Azbazdar Y, De Robertis EM., Bioessays. January 1, 2024; 46 (1): e2300179.                            

Gene expression analysis of the Xenopus laevis early limb bud proximodistal axis., Hudson DT, Bromell JS, Day RC, McInnes T, Ward JM, Beck CW., Dev Dyn. November 1, 2022; 251 (11): 1880-1896.              

A myeloperoxidase enhancer drives myeloid cell-specific labeling in a transgenic frog line., Yamada-Kondo S, Ogawa A, Fukunaga M, Izutsu Y, Kato T, Maéno M., Dev Growth Differ. September 1, 2022; 64 (7): 362-367.        

Evo-Devo of Urbilateria and its larval forms., De Robertis EM, Tejeda-Muñoz N., Dev Biol. July 1, 2022; 487 10-20.        

The m6A(m)-independent role of FTO in regulating WNT signaling pathways., Kim H, Jang S, Lee YS., Life Sci Alliance. February 15, 2022; 5 (5):


The role of Xenopus developmental biology in unraveling Wnt signalling and antero-posterior axis formation., Niehrs C., Dev Biol. February 1, 2022; 482 1-6.

Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly., Gur M, Bendelac-Kapon L, Shabtai Y, Pillemer G, Fainsod A., Front Cell Dev Biol. January 1, 2022; 10 844619.                        

Rab7 is required for mesoderm patterning and gastrulation in Xenopus., Kreis J, Wielath FM, Vick P., Biol Open. July 15, 2021; 10 (7):                                           

Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs., Aztekin C, Hiscock TW, Gurdon J, Jullien J, Marioni J, Simons BD., Development. June 1, 2021; 148 (11):                                             

Pinhead antagonizes Admp to promote notochord formation., Itoh K, Ossipova O, Sokol SY., iScience. May 7, 2021; 24 (6): 102520.                            

Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., Bright AR, van Genesen S, Li Q, Grasso A, Frölich S, van der Sande M, van Heeringen SJ, Veenstra GJC., EMBO J. May 3, 2021; 40 (9): e104913.                        

Establishing embryonic territories in the context of Wnt signaling., Velloso I, Maia LA, Amado NG, Reis AH, He X, Abreu JG., Int J Dev Biol. January 1, 2021; 65 (4-5-6): 227-233.      

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway., Colozza G, Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM., Sci Rep. December 9, 2020; 10 (1): 21555.            

Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains., Kim J, Han W, Park T, Kim EJ, Bang I, Lee HS, Lee HS, Jeong Y, Roh K, Kim J, Kim JS, Kang C, Seok C, Han JK, Choi HJ., Nat Commun. October 23, 2020; 11 (1): 5357.            

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Pinhead signaling regulates mesoderm heterogeneity via the FGF receptor-dependent pathway., Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY., Development. September 11, 2020; 147 (17):                 

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network., Mukherjee S, Chaturvedi P, Rankin SA, Rankin SA, Fish MB, Wlizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KW, Zorn AM., Elife. September 7, 2020; 9                           

The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C., Elife. January 14, 2020; 9                                                                                               

Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway., Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY., Development. January 1, 2020;                                       

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia., Haas M, Gómez Vázquez JL, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Vleminckx K, Walentek P., Cell Rep. September 24, 2019; 28 (13): 3338-3352.e6.                              

Integration of Wnt and FGF signaling in the Xenopus gastrula at TCF and Ets binding sites shows the importance of short-range repression by TCF in patterning the marginal zone., Kjolby RAS, Truchado-Garcia M, Iruvanti S, Harland RM., Development. August 9, 2019; 146 (15):                           

Mechanistic insights from the LHX1-driven molecular network in building the embryonic head., McMahon R, Sibbritt T, Salehin N, Osteil P, Tam PPL., Dev Growth Differ. June 1, 2019; 61 (5): 327-336.

The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M., Dev Biol. May 1, 2019; 449 (1): 1-13.                                  

Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Jalvy S, Veschambre P, Fédou S, Rezvani HR, Thézé N, Thiébaud P., Dev Biol. March 15, 2019; 447 (2): 200-213.                                  

Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis., Harata A, Hirakawa M, Sakuma T, Yamamoto T, Hashimoto C., Dev Growth Differ. February 1, 2019; 61 (2): 186-197.                                

Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation., Haworth K, Samuel L, Black S, Kirilenko P, Latinkic B., Front Physiol. January 1, 2019; 10 155.              

WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. November 28, 2018; 145 (23):                 

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner., Devotta A, Hong CS, Saint-Jeannet JP., Elife. July 23, 2018; 7                             

SATB1 downregulation induced by oxidative stress participates in trophoblast invasion by regulating β-catenin., Rao H, Bai Y, Li Q, Zhuang B, Yuan Y, Liu Y, Peng W, Baker PN, Tong C, Luo X, Qi H., Biol Reprod. June 1, 2018; 98 (6): 810-820.

Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis., Goto T, Ito Y, Michiue T., Dev Growth Differ. May 1, 2018; 60 (4): 226-238.              

Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis., Rankin SA, Rankin SA, McCracken KW, Luedeke DM, Han L, Wells JM, Shannon JM, Zorn AM., Dev Biol. February 1, 2018; 434 (1): 121-132.          

Using Zebrafish to Study Collective Cell Migration in Development and Disease., Olson HM, Nechiporuk AV., Front Cell Dev Biol. January 1, 2018; 6 83.            

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing., Zhang Z, Zhang Z, Jones AE, Wu W, Kim J, Kang Y, Bi X, Gu Y, Popov IK, Renfrow MB, Vassylyeva MN, Vassylyev DG, Giles KE, Chen D, Kumar A, Fan Y, Tong Y, Liu CF, An W, Chang C, Luo J, Chow LT, Wang H., Proc Natl Acad Sci U S A. September 19, 2017; 114 (38): E7949-E7958.                          

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors., Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ., Sci Signal. June 27, 2017; 10 (485):


Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula., Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MDJ, De Robertis EM., Dev Biol. June 15, 2017; 426 (2): 176-187.                                  

Genome-wide identification of Wnt/β-catenin transcriptional targets during Xenopus gastrulation., Kjolby RAS, Harland RM., Dev Biol. June 15, 2017; 426 (2): 165-175.                                    

The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning., Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A., Development. June 15, 2017; 144 (12): 2234-2247.                                      

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G, Thomas BL, Sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup AS, Dale L, Schett G, Zwerina J, Eltawil N, Pitzalis C, Dell'Accio F., Ann Rheum Dis. January 1, 2017; 76 (1): 218-226.              

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue., Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.              

Apolipoprotein C-I mediates Wnt/Ctnnb1 signaling during neural border formation and is required for neural crest development., Yokota C, Åstrand C, Takahashi S, Hagey DW, Stenman JM., Int J Dev Biol. January 1, 2017; 61 (6-7): 415-425.                      

Cholesterol-rich membrane microdomains modulate Wnt/β-catenin morphogen gradient during Xenopus development., Reis AH, Moreno MM, Maia LA, Oliveira FP, Santos AS, Abreu JG., Mech Dev. November 1, 2016; 142 30-39.                        

Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling., Hamilton PW, Sun Y, Henry JJ., Exp Eye Res. April 1, 2016; 145 206-215.          

Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling., Zhao Y, Shi J, Winey M, Klymkowsky MW., Dev Biol. March 15, 2016; 411 (2): 257-265.                      

Ventricular cell fate can be specified until the onset of myocardial differentiation., Caporilli S, Latinkic BV., Mech Dev. February 1, 2016; 139 31-41.                        

Specification of anteroposterior axis by combinatorial signaling during Xenopus development., Carron C, Shi DL., Wiley Interdiscip Rev Dev Biol. January 1, 2016; 5 (2): 150-68.            

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