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Summary Expression Phenotypes Gene Literature (35) GO Terms (2) Nucleotides (187) Proteins (67) Interactants (454) Wiki
XB--481765

Papers associated with tle4



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Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri., Ahuja SK, Murphy PM., J Biol Chem. October 5, 1993; 268 (28): 20691-4.

Cloning and developmental expression of Xenopus cDNAs encoding the Enhancer of split groucho and related proteins., Choudhury BK, Kim J, Kung HF, Li SS., Gene. August 11, 1997; 195 (1): 41-8.

A tight control over Wnt action., Molenaar M, Destrée O., Int J Dev Biol. January 1, 1999; 43 (7): 675-80.    

Keeping a close eye on Wnt-1/wg signaling in Xenopus., Gradl D, Kühl M, Wedlich D., Mech Dev. August 1, 1999; 86 (1-2): 3-15.    

The HMG-box transcription factor XTcf-4 demarcates the forebrain-midbrain boundary., König A, Gradl D, Kühl M, Wedlich D., Mech Dev. May 1, 2000; 93 (1-2): 211-4.    

Identification of two regulatory elements within the high mobility group box transcription factor XTCF-4., Pukrop T, Gradl D, Henningfeld KA, Knochel W, Wedlich D, Kuhl M., J Biol Chem. March 23, 2001; 276 (12): 8968-78.

Bowline, a novel protein localized to the presomitic mesoderm, interacts with Groucho/TLE in Xenopus., Kondow A, Hitachi K, Ikegame T, Asashima M., Int J Dev Biol. January 1, 2006; 50 (5): 473-9.          

HIC-5 is a novel repressor of lymphoid enhancer factor/T-cell factor-driven transcription., Ghogomu SM, van Venrooy S, Ritthaler M, Wedlich D, Gradl D., J Biol Chem. January 20, 2006; 281 (3): 1755-64.            

Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal., Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM., Development. September 1, 2006; 133 (18): 3709-22.                                    

FoxD3 and Grg4 physically interact to repress transcription and induce mesoderm in Xenopus., Yaklichkin S, Steiner AB, Lu Q, Kessler DS., J Biol Chem. January 26, 2007; 282 (4): 2548-57.

Bowline mediates association of the transcriptional corepressor XGrg-4 with Tbx6 during somitogenesis in Xenopus., Kondow A, Hitachi K, Okabayashi K, Hayashi N, Asashima M., Biochem Biophys Res Commun. August 10, 2007; 359 (4): 959-64.        

Hes6 is required for MyoD induction during gastrulation., Murai K, Vernon AE, Philpott A, Jones P., Dev Biol. December 1, 2007; 312 (1): 61-76.            

Autoregulation of XTcf-4 depends on a Lef/Tcf site on the XTcf-4 promoter., Koenig SF, Lattanzio R, Mansperger K, Rupp RA, Wedlich D, Gradl D., Genesis. February 1, 2008; 46 (2): 81-6.

Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus., van Venrooy S, Fichtner D, Kunz M, Wedlich D, Gradl D., BMC Dev Biol. August 7, 2008; 8 77.                                

The function of the Aristaless-related homeobox (Arx) gene product as a transcriptional repressor is diminished by mutations associated with X-linked mental retardation (XLMR)., Fullenkamp AN, El-Hodiri HM., Biochem Biophys Res Commun. December 5, 2008; 377 (1): 73-8.            

The Xenopus Bowline/Ripply family proteins negatively regulate the transcriptional activity of T-box transcription factors., Hitachi K, Danno H, Tazumi S, Aihara Y, Uchiyama H, Okabayashi K, Kondow A, Asashima M., Int J Dev Biol. January 1, 2009; 53 (4): 631-9.                    

Developmental expression patterns of candidate cofactors for vertebrate six family transcription factors., Neilson KM, Pignoni F, Yan B, Moody SA., Dev Dyn. December 1, 2010; 239 (12): 3446-66.                                                                          

Conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning., Kozmikova I, Smolikova J, Vlcek C, Kozmik Z., PLoS One. February 3, 2011; 6 (2): e14650.                  

EphrinB1 interacts with the transcriptional co-repressor Groucho/xTLE4., Kamata T, Bong YS, Mood K, Park MJ, Nishanian TG, Lee HS., BMB Rep. March 1, 2011; 44 (3): 199-204.

XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling., Hanson AJ, Wallace HA, Freeman TJ, Beauchamp RD, Lee LA, Lee E, Lee E., Mol Cell. March 9, 2012; 45 (5): 619-28.  

Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate., Neilson KM, Klein SL, Mhaske P, Mood K, Daar IO, Moody SA., Dev Biol. May 15, 2012; 365 (2): 363-75.                        

SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest., Lee PC, Taylor-Jaffe KM, Nordin KM, Prasad MS, Lander RM, LaBonne C., J Cell Biol. September 3, 2012; 198 (5): 799-813.              

The vestibuloocular reflex of tadpoles (Xenopus laevis) after knock-down of the isthmus-related transcription factor XTcf-4., Horn ER, El-Yamany NA, Gradl D., J Exp Biol. February 15, 2013; 216 (Pt 4): 733-41.

Conserved structural domains in FoxD4L1, a neural forkhead box transcription factor, are required to repress or activate target genes., Klein SL, Neilson KM, Orban J, Yaklichkin S, Hoffbauer J, Mood K, Daar IO, Moody SA., PLoS One. April 4, 2013; 8 (4): e61845.                  

The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins., Li HY, Grifone R, Saquet A, Carron C, Shi DL., Development. December 1, 2013; 140 (24): 4903-13.                                

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression., Kaltenbrun E, Greco TM, Slagle CE, Kennedy LM, Li T, Cristea IM, Conlon FL., J Proteome Res. December 6, 2013; 12 (12): 5395-409.

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        

Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development., Zhang S, Li J, Lea R, Vleminckx K, Vleminckx K, Amaya E., Development. December 1, 2014; 141 (24): 4794-805.                            

Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm., Gaur S, Mandelbaum M, Herold M, Majumdar HD, Neilson KM, Maynard TM, Mood K, Daar IO, Moody SA., Genesis. June 1, 2016; 54 (6): 334-49.                          

FoxH1 mediates a Grg4 and Smad2 dependent transcriptional switch in Nodal signaling during Xenopus mesoderm development., Reid CD, Steiner AB, Yaklichkin S, Lu Q, Wang S, Hennessy M, Kessler DS., Dev Biol. June 1, 2016; 414 (1): 34-44.                  

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

Barhl2 maintains T cell factors as repressors and thereby switches off the Wnt/β-Catenin response driving Spemann organizer formation., Sena E, Rocques N, Borday C, Muhamad Amin HS, Parain K, Sitbon D, Chesneau A, Durand BC., Development. May 22, 2019; 146 (10):                                             

Influence of Sox protein SUMOylation on neural development and regeneration., Chang KC., Neural Regen Res. March 1, 2022; 17 (3): 477-481.      

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation., Jourdeuil K, Neilson KM, Cousin H, Tavares ALP, Majumdar HD, Alfandari D, Alfandari D, Moody SA., Front Cell Dev Biol. January 1, 2023; 11 1274788.          

Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes., Neal SJ, Rajasekaran A, Jusić N, Taylor L, Read M, Alfandari D, Alfandari D, Pignoni F, Moody SA., J Exp Zool B Mol Dev Evol. October 13, 2023;             

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