Papers associated with gli3

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	GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity., Ruppert JM, Vogelstein B, Arheden K, Kinzler KW., Mol Cell Biol. October 1, 1990; 10 (10): 5408-15.
	GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families., Vortkamp A, Gessler M, Grzeschik KH., Nature. August 8, 1991; 352 (6335): 539-40.
	Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) and the mouse mutant extra toes (Xt)., Vortkamp A, Franz T, Gessler M, Grzeschik KH., Mamm Genome. January 1, 1992; 3 (8): 461-3.
	Gli3 expression is affected in the morphogenetic mouse mutants add and Xt., Schimmang T, van der Hoeven F, Rüther U., Prog Clin Biol Res. January 1, 1993; 383A 153-61.
	Isolation of a yeast artificial chromosome contig spanning the Greig cephalopolysyndactyly syndrome (GCPS) gene region., Vortkamp A, Gessler M, Le Paslier D, Elaswarapu R, Smith S, Grzeschik KH., Genomics. August 1, 1994; 22 (3): 563-8.
	Identification of optimized target sequences for the GLI3 zinc finger protein., Vortkamp A, Gessler M, Grzeschik KH., DNA Cell Biol. July 1, 1995; 14 (7): 629-34.
	Apoptosis in the developing CNS., Naruse I, Keino H., Prog Neurobiol. October 1, 1995; 47 (2): 135-55.
	Cloning and sequence analysis of the murine Gli3 cDNA., Thien H, Büscher D, Rüther U., Biochim Biophys Acta. July 17, 1996; 1307 (3): 267-9.
	Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development., Marigo V, Johnson RL, Vortkamp A, Tabin CJ., Dev Biol. November 25, 1996; 180 (1): 273-83.
	Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development., Mo R, Freer AM, Zinyk DL, Crackower MA, Michaud J, Heng HH, Chik KW, Shi XM, Tsui LC, Cheng SH, Joyner AL, Hui C., Development. January 1, 1997; 124 (1): 113-23.
	Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region., Hughes DC, Allen J, Morley G, Sutherland K, Ahmed W, Prosser J, Lettice L, Allan G, Mattei MG, Farrall M, Hill RE., Genomics. January 15, 1997; 39 (2): 205-15.
	Multigenic control of the localization of the zone of polarizing activity in limb morphogenesis in the mouse., Masuya H, Sagai T, Moriwaki K, Shiroishi T., Dev Biol. February 1, 1997; 182 (1): 42-51.
	Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development., Büscher D, Bosse B, Heymer J, Rüther U., Mech Dev. March 1, 1997; 62 (2): 175-82.
	GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome., Kang S, Graham JM, Olney AH, Biesecker LG., Nat Genet. March 1, 1997; 15 (3): 266-8.
	A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro., Sasaki H, Hui C, Nakafuku M, Kondoh H., Development. April 1, 1997; 124 (7): 1313-22.
	A role for Xenopus Gli-type zinc finger proteins in the early embryonic patterning of mesoderm and neuroectoderm., Marine JC, Bellefroid EJ, Pendeville H, Martial JA, Pieler T., Mech Dev. May 1, 1997; 63 (2): 211-25.
	Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Lee J, Platt KA, Censullo P, Ruiz i Altaba A., Development. July 1, 1997; 124 (13): 2537-52.
	Evidence for the involvement of the Gli gene family in embryonic mouse lung development., Grindley JC, Bellusci S, Perkins D, Hogan BL., Dev Biol. August 15, 1997; 188 (2): 337-48.
	Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4., Dunn NR, Winnier GE, Hargett LK, Schrick JJ, Fogo AB, Hogan BL., Dev Biol. August 15, 1997; 188 (2): 235-47.
	Point mutations in human GLI3 cause Greig syndrome., Wild A, Kalff-Suske M, Vortkamp A, Bornholdt D, König R, Grzeschik KH., Hum Mol Genet. October 1, 1997; 6 (11): 1979-84.
	Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours., Dahmane N, Lee J, Lee J, Robins P, Heller P, Ruiz i Altaba A., Nature. October 23, 1997; 389 (6653): 876-81.
	Mutation in GLI3 in postaxial polydactyly type A., Radhakrishna U, Wild A, Grzeschik KH, Antonarakis SE., Nat Genet. November 1, 1997; 17 (3): 269-71.
	Strike three for GLI3., Biesecker LG., Nat Genet. November 1, 1997; 17 (3): 259-60.
	Gene structure and allelic expression assay of the human GLI3 gene., Kang S, Rosenberg M, Ko VD, Biesecker LG., Hum Genet. December 1, 1997; 101 (2): 154-7.
	Expression profile of Gli family members and Shh in normal and mutant mouse limb development., Büscher D, Rüther U., Dev Dyn. January 1, 1998; 211 (1): 88-96.
	The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice., Grove EA, Tole S, Limon J, Yip L, Ragsdale CW., Development. June 1, 1998; 125 (12): 2315-25.
	Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog., Ruiz i Altaba A., Development. June 1, 1998; 125 (12): 2203-12.
	The XtJ allele generates a Gli3 fusion transcript., Büscher D, Grotewold L, Rüther U., Mamm Genome. August 1, 1998; 9 (8): 676-8.
	Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus., Kuo JS, Patel M, Gamse J, Merzdorf C, Liu X, Apekin V, Sive H., Development. August 1, 1998; 125 (15): 2867-82.
	The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants., Hardcastle Z, Mo R, Hui CC, Sharpe PT., Development. August 1, 1998; 125 (15): 2803-11.
	Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus., Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC., Nat Genet. September 1, 1998; 20 (1): 54-7.
	PTCH gene mutations in invasive transitional cell carcinoma of the bladder., McGarvey TW, Maruta Y, Tomaszewski JE, Linnenbach AJ, Malkowicz SB., Oncogene. September 3, 1998; 17 (9): 1167-72.
	The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development., Takahashi M, Tamura K, Tamura K, Büscher D, Masuya H, Yonei-Tamura S, Matsumoto K, Naitoh-Matsuo M, Takeuchi J, Ogura K, Shiroishi T, Ogura T, Izpisúa Belmonte JC., Development. November 1, 1998; 125 (22): 4417-25.
	Carboxy-terminally truncated Gli3 proteins associate with Smads., Liu F, Massagué J, Ruiz i Altaba A., Nat Genet. December 1, 1998; 20 (4): 325-6.
	Progress toward understanding craniofacial malformations., Nuckolls GH, Shum L, Slavkin HC., Cleft Palate Craniofac J. January 1, 1999; 36 (1): 12-26.
	Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity., Zúñiga A, Zeller R., Development. January 1, 1999; 126 (1): 13-21.
	The mouse mutation Pdn (Polydactyly Nagoya) is caused by the integration of a retrotransposon into the Gli3 gene., Thien H, Rüther U., Mamm Genome. March 1, 1999; 10 (3): 205-9.
	GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization., Shin SH, Kogerman P, Lindström E, Toftgárd R, Biesecker LG., Proc Natl Acad Sci U S A. March 16, 1999; 96 (6): 2880-4.
	Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3., Dai P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M, Ishii S., J Biol Chem. March 19, 1999; 274 (12): 8143-52.
	Gli proteins encode context-dependent positive and negative functions: implications for development and disease., Ruiz i Altaba A., Development. June 1, 1999; 126 (14): 3205-16.
	Gli3 is required for Emx gene expression during dorsal telencephalon development., Theil T, Alvarez-Bolado G, Walter A, Rüther U., Development. August 1, 1999; 126 (16): 3561-71.
	Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators., Pearse RV, Collier LS, Scott MP, Tabin CJ., Dev Biol. August 15, 1999; 212 (2): 323-36.
	The phenotypic spectrum of GLI3 morphopathies includes autosomal dominant preaxial polydactyly type-IV and postaxial polydactyly type-A/B; No phenotype prediction from the position of GLI3 mutations., Radhakrishna U, Bornholdt D, Scott HS, Patel UC, Rossier C, Engel H, Bottani A, Chandal D, Blouin JL, Solanki JV, Grzeschik KH, Antonarakis SE., Am J Hum Genet. September 1, 1999; 65 (3): 645-55.
	Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactyly syndrome., Kalff-Suske M, Wild A, Topp J, Wessling M, Jacobsen EM, Bornholdt D, Engel H, Heuer H, Aalfs CM, Ausems MG, Barone R, Herzog A, Heutink P, Homfray T, Gillessen-Kaesbach G, König R, Kunze J, Meinecke P, Müller D, Rizzo R, Strenge S, Superti-Furga A, Grzeschik KH., Hum Mol Genet. September 1, 1999; 8 (9): 1769-77.
	Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling., Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H., Development. September 1, 1999; 126 (17): 3915-24.
	Functional association of retinoic acid and hedgehog signaling in Xenopus primary neurogenesis., Franco PG, Paganelli AR, López SL, Carrasco AE., Development. October 1, 1999; 126 (19): 4257-65.
	Distinct and regulated activities of human Gli proteins in Drosophila., von Mering C, Basler K., Curr Biol. November 18, 1999; 9 (22): 1319-22.
	Zic1 regulates the patterning of vertebral arches in cooperation with Gli3., Aruga J, Mizugishi K, Koseki H, Imai K, Balling R, Noda T, Mikoshiba K., Mech Dev. December 1, 1999; 89 (1-2): 141-50.
	Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J)., Tole S, Ragsdale CW, Grove EA., Dev Biol. January 15, 2000; 217 (2): 254-65.
	Boy with syndactylies, macrocephaly, and severe skeletal dysplasia: not a new syndrome, but two dominant mutations (GLI3 E543X and COL2A1 G973R) in the same individual., Sobetzko D, Eich G, Kalff-Suske M, Grzeschik KH, Superti-Furga A., Am J Med Genet. January 31, 2000; 90 (3): 239-42.

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