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Summary Expression Phenotypes Gene Literature (86) GO Terms (3) Nucleotides (387) Proteins (49) Interactants (475) Wiki
XB--486986

Papers associated with tnni3



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Expression cloning of a human B1 bradykinin receptor., Menke JG, Borkowski JA, Bierilo KK, MacNeil T, Derrick AW, Schneck KA, Ransom RW, Strader CD, Linemeyer DL, Hess JF., J Biol Chem. August 26, 1994; 269 (34): 21583-6.

Cardiac troponin I is a heart-specific marker in the Xenopus embryo: expression during abnormal heart morphogenesis., Drysdale TA, Tonissen KF, Patterson KD, Crawford MJ, Krieg PA., Dev Biol. October 1, 1994; 165 (2): 432-41.              

Former neuritic pathways containing endogenous neural agrin have high synaptogenic activity., Cohen MW, Moody-Corbett F, Godfrey EW., Dev Biol. February 1, 1995; 167 (2): 458-68.              

Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists., Claude PA, Wotta DR, Zhang XH, Prather PL, McGinn TM, Erickson LJ, Loh HH, Law PY., Proc Natl Acad Sci U S A. June 11, 1996; 93 (12): 5715-9.

Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia., Cleaver OB, Patterson KD, Krieg PA., Development. November 1, 1996; 122 (11): 3549-56.          

Apoptosis in Xenopus tadpole tail muscles involves Bax-dependent pathways., Sachs LM, Abdallah B, Hassan A, Levi G, De Luze A, Reed JC, Demeneix BA., FASEB J. August 1, 1997; 11 (10): 801-8.

Retinoic acid can block differentiation of the myocardium after heart specification., Drysdale TA, Patterson KD, Saha M, Krieg PA., Dev Biol. August 15, 1997; 188 (2): 205-15.          

Differential expression of nucleoside diphosphate kinases (NDPK/NM23) during Xenopus early development., Ouatas T, Sélo M, Sadji Z, Hourdry J, Denis H, Mazabraud A., Int J Dev Biol. January 1, 1998; 42 (1): 43-52.              

Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner., Fu Y, Yan W, Mohun TJ, Evans SM., Development. November 1, 1998; 125 (22): 4439-49.            

Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5., Grow MW, Krieg PA., Dev Biol. December 1, 1998; 204 (1): 187-96.      

The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping., Campione M, Steinbeisser H, Schweickert A, Deissler K, van Bebber F, Lowe LA, Nowotschin S, Viebahn C, Haffter P, Kuehn MR, Blum M., Development. March 1, 1999; 126 (6): 1225-34.            

The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus., Cheng AM, Thisse B, Thisse C, Wright CV., Development. March 1, 2000; 127 (5): 1049-61.                

BMP signaling is required for heart formation in vertebrates., Shi Y, Shi Y, Katsev S, Cai C, Evans S., Dev Biol. August 15, 2000; 224 (2): 226-37.          

Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis., Rones MS, McLaughlin KA, Raffin M, Mercola M., Development. September 1, 2000; 127 (17): 3865-76.                  

Ion interactions in the high-affinity binding locus of a voltage-gated Ca(2+) channel., Cloues RK, Cibulsky SM, Sather WA., J Gen Physiol. October 1, 2000; 116 (4): 569-86.                      

Fox (forkhead) genes are involved in the dorso-ventral patterning of the Xenopus mesoderm., El-Hodiri H, Bhatia-Dey N, Kenyon K, Ault K, Dirksen M, Jamrich M., Int J Dev Biol. January 1, 2001; 45 (1): 265-71.        

Wnt antagonism initiates cardiogenesis in Xenopus laevis., Schneider VA, Mercola M., Genes Dev. February 1, 2001; 15 (3): 304-15.        

The Twisted gastrulation family of proteins, together with the IGFBP and CCN families, comprise the TIC superfamily of cysteine rich secreted factors., Vilmos P, Gaudenz K, Hegedus Z, Marsh JL., Mol Pathol. October 1, 2001; 54 (5): 317-23.

Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation., Habets PE, Moorman AF, Clout DE, van Roon MA, Lingbeek M, van Lohuizen M, Campione M, Christoffels VM., Genes Dev. May 15, 2002; 16 (10): 1234-46.

The slow isoform of Xenopus troponin I is expressed in developing skeletal muscle but not in the heart., Warkman AS, Atkinson BG., Mech Dev. July 1, 2002; 115 (1-2): 143-6.                      

Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells., Hidaka K, Lee JK, Lee JK, Kim HS, Ihm CH, Iio A, Ogawa M, Nishikawa S, Kodama I, Morisaki T., FASEB J. April 1, 2003; 17 (6): 740-2.

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos., Sheldahl LC, Slusarski DC, Pandur P, Miller JR, Kühl M, Moon RT., J Cell Biol. May 26, 2003; 161 (4): 769-77.            

Amphibian in vitro heart induction: a simple and reliable model for the study of vertebrate cardiac development., Ariizumi T, Kinoshita M, Yokota C, Takano K, Fukuda K, Moriyama N, Malacinski GM, Asashima M., Int J Dev Biol. September 1, 2003; 47 (6): 405-10.      

Regulation of heart size in Xenopus laevis., Garriock RJ, Drysdale TA., Differentiation. October 1, 2003; 71 (8): 506-15.            

Amphibian cardiac troponin I gene's organization, developmental expression, and regulatory properties are different from its mammalian homologue., Warkman AS, Atkinson BG., Dev Dyn. February 1, 2004; 229 (2): 275-88.

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            

Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis., Brown DD, Martz SN, Binder O, Goetz SC, Price BM, Smith JC, Conlon FL., Development. February 1, 2005; 132 (3): 553-63.                

Myocardin is sufficient and necessary for cardiac gene expression in Xenopus., Small EM, Warkman AS, Wang DZ, Sutherland LB, Olson EN, Krieg PA., Development. March 1, 2005; 132 (5): 987-97.            

SOX7 and SOX18 are essential for cardiogenesis in Xenopus., Zhang C, Basta T, Klymkowsky MW., Dev Dyn. December 1, 2005; 234 (4): 878-91.                    

Retinoic acid signaling is essential for formation of the heart tube in Xenopus., Collop AH, Broomfield JA, Chandraratna RA, Yong Z, Deimling SJ, Kolker SJ, Weeks DL, Drysdale TA., Dev Biol. March 1, 2006; 291 (1): 96-109.                  

TBX5 is required for embryonic cardiac cell cycle progression., Goetz SC, Brown DD, Conlon FL., Development. July 1, 2006; 133 (13): 2575-84.                

Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis., Inui M, Fukui A, Ito Y, Asashima M., Dev Biol. October 1, 2006; 298 (1): 188-200.                

Characterization of myeloid cells derived from the anterior ventral mesoderm in the Xenopus laevis embryo., Tashiro S, Sedohara A, Asashima M, Izutsu Y, Maéno M., Dev Growth Differ. October 1, 2006; 48 (8): 499-512.                    

Reduction of XNkx2-10 expression leads to anterior defects and malformation of the embryonic heart., Allen BG, Allen-Brady K, Weeks DL., Mech Dev. October 1, 2006; 123 (10): 719-29.          

ADMP2 is essential for primitive blood and heart development in Xenopus., Kumano G, Ezal C, Smith WC., Dev Biol. November 15, 2006; 299 (2): 411-23.                

Multiple functions of Cerberus cooperate to induce heart downstream of Nodal., Foley AC, Korol O, Timmer AM, Mercola M., Dev Biol. March 1, 2007; 303 (1): 57-65.        

The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos., Vonica A, Brivanlou AH., Dev Biol. March 1, 2007; 303 (1): 281-94.              

The amphibian second heart field: Xenopus islet-1 is required for cardiovascular development., Brade T, Gessert S, Kühl M, Pandur P., Dev Biol. November 15, 2007; 311 (2): 297-310.          

HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus., Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R., J Biol Chem. April 25, 2008; 283 (17): 11841-9.                        

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis., Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M, Komuro I., Nature. July 17, 2008; 454 (7202): 345-9.                        

GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos., Haworth KE, Kotecha S, Mohun TJ, Latinkic BV., BMC Dev Biol. July 28, 2008; 8 74.                        

Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1., Movassagh M, Philpott A., Cardiovasc Res. August 1, 2008; 79 (3): 436-47.                                

DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells., Gessert S, Maurus D, Brade T, Walther P, Pandur P, Kühl M., Dev Biol. September 1, 2008; 321 (1): 150-61.            

A crucial role for hnRNP K in axon development in Xenopus laevis., Liu Y, Gervasi C, Szaro BG., Development. September 1, 2008; 135 (18): 3125-35.                

GATA transcription factors integrate Wnt signalling during heart development., Afouda BA, Martin J, Liu F, Ciau-Uitz A, Patient R, Hoppler S., Development. October 1, 2008; 135 (19): 3185-90.        

Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling., Li Y, Rankin SA, Rankin SA, Sinner D, Kenny AP, Krieg PA, Zorn AM., Genes Dev. November 1, 2008; 22 (21): 3050-63.                        

Wnt6 signaling regulates heart muscle development during organogenesis., Lavery DL, Martin J, Turnbull YD, Hoppler S., Dev Biol. November 15, 2008; 323 (2): 177-88.            

Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5., Espinoza-Lewis RA, Yu L, He F, Liu H, Tang R, Shi J, Sun X, Martin JF, Wang D, Yang J, Chen Y., Dev Biol. March 15, 2009; 327 (2): 376-85.      

In vitro organogenesis from undifferentiated cells in Xenopus., Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T., Dev Dyn. June 1, 2009; 238 (6): 1309-20.                      

Comparative gene expression analysis and fate mapping studies suggest an early segregation of cardiogenic lineages in Xenopus laevis., Gessert S, Kühl M., Dev Biol. October 15, 2009; 334 (2): 395-408.          

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