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Deletion of sf3b4 causes splicing defects and gene dysregulation that disrupt craniofacial development and survival. , Griffin C , Coppenrath K , Khan D, Lin Z, Horb M , Saint-Jeannet JP ., Dis Model Mech. March 1, 2025; 18 (3):
Single-cell atlas comparison across vertebrates reveals auditory cell evolution and mechanisms for hair cell regeneration. , Wang Y, Wang H, Zhang P, Zhu B, Li W , Zhao X, Yan M , Song X, Lai F , Dong J, Cui J, Guo X, Wu HJ, Li J., Commun Biol. December 19, 2024; 7 (1): 1648.
Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans. , Wen MH, Barbosa Triana H, Butler R, Hu HW, Dai YH, Lawrence N, Hong JJ, Garrett N, Jones-Green R, Rawlins EL, Dong Z, Koziol MJ, Gurdon JB ., Biol Open. March 1, 2024; 13 (3):
Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation. , Santoni M, Meneau F, Sekhsoukh N, Castella S, Le T, Miot M, Daldello EM., Cell Rep. February 27, 2024; 43 (2): 113782.
Overlapping action of T3 and T4 during Xenopus laevis development. , Tribondeau A, Du Pasquier D, Benchouaia M, Blugeon C, Buisine N , Sachs LM ., Front Endocrinol (Lausanne). January 1, 2024; 15 1360188.
Metamorphic gene regulation programs in Xenopus tropicalis tadpole brain. , Raj S, Sifuentes CJ, Kyono Y, Denver RJ ., PLoS One. January 1, 2023; 18 (6): e0287858.
Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment. , Satou-Kobayashi Y, Kim JD , Fukamizu A, Asashima M ., Sci Rep. July 15, 2021; 11 (1): 14537.
Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis. , Wu HY, Zhou YM, Liao ZQ, Zhong JW, Liu YB , Zhao H , Liang CQ, Huang RJ, Park KS, Feng SS, Zheng L, Cai DQ, Qi XF., NPJ Regen Med. June 29, 2021; 6 (1): 36.
PAK1 Regulates MEC-17 Acetyltransferase Activity and Microtubule Acetylation during Proplatelet Extension. , van Dijk J, Bompard G, Rabeharivelo G, Cau J, Delsert C, Morin N ., Int J Mol Sci. October 13, 2020; 21 (20):
Developmentally-programmed cellular senescence is conserved and widespread in zebrafish. , Da Silva-Álvarez S, Guerra-Varela J, Sobrido-Cameán D, Quelle A, Barreiro-Iglesias A, Sánchez L, Collado M., Aging (Albany NY). September 29, 2020; 12 (18): 17895-17901.
The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy. , Thawani A, Rale MJ , Coudray N, Bhabha G, Stone HA, Shaevitz JW, Petry S ., Elife. June 15, 2020; 9
Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma. , Feng C, Zhang HL , Zeng A, Bai M, Wang XJ ., Mol Ther Nucleic Acids. June 5, 2020; 20 186-195.
TPX2 silencing exerts anti‑tumor effects on hepatocellular carcinoma by regulating the PI3K/AKT signaling pathway. , Huang DH, Jian J, Li S, Zhang Y , Liu LZ., Int J Mol Med. December 1, 2019; 44 (6): 2113-2122.
HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer. , Li F, Su M, Zhao H , Xie W, Cao S, Xu Y , Xu Y , Chen W, Wang L, Hou L, Tan W., Am J Transl Res. November 15, 2019; 11 (11): 7035-7048.
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer. , Chen M, Zhang H , Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.
Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development. , Konjikusic MJ, Yeetong P, Boswell CW, Lee C , Lee C , Roberson EC, Ittiwut R, Suphapeetiporn K, Ciruna B, Gurnett CA, Wallingford JB , Shotelersuk V, Gray RS ., PLoS Genet. November 6, 2018; 14 (11): e1007817.
PDGF-A suppresses contact inhibition during directional collective cell migration. , Nagel M, Winklbauer R ., Development. July 5, 2018; 145 (13):
Regulation of c- MYC transcriptional activity by transforming growth factor-beta 1-stimulated clone 22. , Zheng L, Suzuki H, Nakajo Y, Nakano A, Kato M., Cancer Sci. February 1, 2018; 109 (2): 395-402.
RNAs coordinate nuclear envelope assembly and DNA replication through ELYS recruitment to chromatin. , Aze A, Fragkos M, Bocquet S, Cau J, Méchali M., Nat Commun. December 14, 2017; 8 (1): 2130.
Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells. , Zhang Z , Lei A, Xu L, Chen L, Chen Y , Zhang X, Gao Y, Yang X, Zhang M, Cao Y , Cao Y ., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.
Translational profiling of retinal ganglion cell optic nerve regeneration in Xenopus laevis. , Whitworth GB, Misaghi BC, Rosenthal DM, Mills EA, Heinen DJ, Watson AH, Ives CW, Ali SH, Bezold K , Marsh-Armstrong N , Watson FL ., Dev Biol. June 15, 2017; 426 (2): 360-373.
Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish. , Xiao C, Gao L, Hou Y, Xu C, Chang N, Wang F, Hu K, He A, Luo Y, Wang J , Peng J, Tang F, Zhu X, Xiong JW., Nat Commun. December 8, 2016; 7 13787.
TPX2 promotes glioma cell proliferation and invasion via activation of the AKT signaling pathway. , Gu JJ, Zhang JH, Chen HJ , Wang SS., Oncol Lett. December 1, 2016; 12 (6): 5015-5022.
Small GTPases Rab8a and Rab11a Are Dispensable for Rhodopsin Transport in Mouse Photoreceptors. , Ying G, Gerstner CD, Frederick JM, Boye SL, Hauswirth WW, Baehr W., PLoS One. August 16, 2016; 11 (8): e0161236.
CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart. , Blech-Hermoni Y, Sullivan CB, Jenkins MW, Wessely O , Ladd AN., Dev Dyn. August 1, 2016; 245 (8): 854-73.
MutSα maintains the mismatch repair capability by inhibiting PCNA unloading. , Kawasoe Y, Tsurimoto T, Nakagawa T, Masukata H, Takahashi TS., Elife. July 12, 2016; 5
Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. , He D, Marie C, Zhao C, Kim B, Wang J , Deng Y, Clavairoly A, Frah M, Wang H, He X , Hmidan H, Jones BV, Witte D, Zalc B , Zhou X , Choo DI, Martin DM, Parras C, Lu QR., Nat Neurosci. May 1, 2016; 19 (5): 678-89.
YAP controls retinal stem cell DNA replication timing and genomic stability. , Cabochette P, Vega-Lopez G, Bitard J, Parain K , Chemouny R, Masson C, Borday C, Hedderich M, Henningfeld KA , Locker M , Bronchain O , Perron M ., Elife. September 22, 2015; 4 e08488.
Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay. , Lion M, Raimondi I, Donati S, Jousson O, Ciribilli Y, Inga A., PLoS One. February 10, 2015; 10 (2): e0116177.
Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3. , Juraver-Geslin HA , Durand BC ., Genesis. February 1, 2015; 53 (2): 203-24.
Initiation and maintenance of pluripotency gene expression in the absence of cohesin. , Lavagnolli T, Gupta P, Hörmanseder E , Mira-Bontenbal H, Dharmalingam G, Carroll T , Gurdon JB , Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.
EphA4-dependent Brachyury expression is required for dorsal mesoderm involution in the Xenopus gastrula. , Evren S, Wen JW, Luu O, Damm EW, Nagel M, Winklbauer R ., Development. October 1, 2014; 141 (19): 3649-61.
Thymine DNA glycosylase is a CRL4Cdt2 substrate. , Slenn TJ, Morris B, Havens CG, Freeman RM, Takahashi TS, Walter JC ., J Biol Chem. August 15, 2014; 289 (33): 23043-23055.
FGFR1 signaling stimulates proliferation of human mesenchymal stem cells by inhibiting the cyclin-dependent kinase inhibitors p21(Waf1) and p27( Kip1). , Dombrowski C, Helledie T, Ling L, Grünert M, Canning CA , Jones CM , Hui JH, Nurcombe V, van Wijnen AJ, Cool SM., Stem Cells. December 1, 2013; 31 (12): 2724-36.
PCNA promotes processive DNA end resection by Exo1. , Chen X , Paudyal SC, Chin RI, You Z., Nucleic Acids Res. November 1, 2013; 41 (20): 9325-38.
Myb promotes centriole amplification and later steps of the multiciliogenesis program. , Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T , Kintner C , Krasnow MA., Development. October 1, 2013; 140 (20): 4277-86.
Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation. , Zhu XN, Kim DH, Lin HR, Budhavarapu VN, Rosenbaum HB, Mueller PR , Yew PR., Cell Div. April 22, 2013; 8 (1): 5.
PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth. , Santiago-Medina M, Gregus KA, Gomez TM ., J Cell Sci. March 1, 2013; 126 (Pt 5): 1122-33.
Spatial and temporal expressions of prune reveal a role in Müller gliogenesis during Xenopus retinal development. , Bilitou A, De Marco N , Bello AM, Garzia L, Carotenuto P, Kim M , Campanella C, Ohnuma S , Zollo M ., Gene. November 1, 2012; 509 (1): 93-103.
The endocytic adapter E- Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling. , Jean S, Tremblay MG, Herdman C, Guillou F, Moss T ., Biol Open. August 15, 2012; 1 (8): 731-8.
The p21-activated kinase Pak1 regulates induction and migration of the neural crest in Xenopus. , Bisson N, Wedlich D , Moss T ., Cell Cycle. April 1, 2012; 11 (7): 1316-24.
Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2. , Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC ., J Biol Chem. March 30, 2012; 287 (14): 11410-21.
Xaml1/ Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus. , Park BY, Hong CS , Weaver JR, Rosocha EM, Saint-Jeannet JP ., Dev Biol. February 1, 2012; 362 (1): 65-75.
Pak6 protein kinase is a novel effector of an atypical Rho family GTPase Chp/ RhoV. , Shepelev MV, Korobko IV., Biochemistry (Mosc). January 1, 2012; 77 (1): 26-32.
Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations. , Zimmermann I, Marabelli A, Bertozzi C, Sivilotti LG, Dutzler R., PLoS Biol. January 1, 2012; 10 (11): e1001429.
Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants. , Sapetto-Rebow B, McLoughlin SC, O'Shea LC, O'Leary O, Willer JR, Alvarez Y, Collery R, O'Sullivan J, Van Eeden F, Hensey C, Kennedy BN., BMC Dev Biol. November 23, 2011; 11 71.
The development of the adult intestinal stem cells: Insights from studies on thyroid hormone-dependent amphibian metamorphosis. , Shi YB , Hasebe T , Fu L, Fujimoto K , Ishizuya-Oka A ., Cell Biosci. September 6, 2011; 1 (1): 30.
WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. , Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP., J Biol Chem. August 26, 2011; 286 (34): 30171-80.
Mechanism of CRL4( Cdt2), a PCNA-dependent E3 ubiquitin ligase. , Havens CG, Walter JC ., Genes Dev. August 1, 2011; 25 (15): 1568-82.
VentX trans-activates p53 and p16ink4a to regulate cellular senescence. , Wu X, Gao H, Ke W, Hager M, Xiao S, Freeman MR, Zhu Z., J Biol Chem. April 8, 2011; 286 (14): 12693-701.