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Summary Expression Phenotypes Gene Literature (428) GO Terms (11) Nucleotides (101) Proteins (30) Interactants (2288) Wiki
XB-GENEPAGE-488038

Papers associated with shh



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49 paper(s) referencing morpholinos

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referenced by:


Pinhead antagonizes Admp to promote notochord formation., Itoh K, Ossipova O, Sokol SY., iScience. June 25, 2021; 24 (6): 102520.                            


Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT, Willsey HR., Genesis. January 1, 2021; 59 (1-2): e23405.          


A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone., Kakebeen AD, Huebner RJ, Shindo A, Kwon K, Kwon T, Wills AE, Wallingford JB., Dev Dyn. January 1, 2021; 250 (5): 717-731.              


Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience., Willsey HR, Exner CRT, Xu Y, Xu Y, Everitt A, Sun N, Wang B, Dea J, Schmunk G, Zaltsman Y, Teerikorpi N, Kim A, Anderson AS, Shin D, Seyler M, Nowakowski TJ, Harland RM, Willsey AJ, State MW., Neuron. January 1, 2021; 109 (5): 788-804.e8.


Thyroid Hormone Receptor Is Essential for Larval Epithelial Apoptosis and Adult Epithelial Stem Cell Development but Not Adult Intestinal Morphogenesis during Xenopus tropicalis Metamorphosis., Shibata Y, Tanizaki Y, Zhang H, Lee H, Dasso M, Shi YB, Shi YB., Cells. January 1, 2021; 10 (3):                             


Rab7 is required for mesoderm patterning and gastrulation in Xenopus., Kreis J, Wielath FM, Vick P., Biol Open. January 1, 2021; 10 (7):                               


Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development., Rankin SA, Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, Ikegami K, Herriges MJ, Moskowitz IP, Zorn AM., Elife. January 1, 2021; 10


Model systems for regeneration: Xenopus., Phipps LS, Marshall L, Dorey K, Amaya E., Development. January 1, 2020; 147 (6):           


RA Signaling in Limb Development and Regeneration in Different Species., Maden M., Subcell Biochem. January 1, 2020; 95 87-117.


The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation., Wang Y, Wang H, Yan Z, Li G, Hu G, Zhang H, Huang D, Wang Y, Zhang X, Yan Y, Lu Q, Cheng M, Luo S., Cell Commun Signal. January 1, 2020; 18 (1): 116.              


TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. January 1, 2020; 9                                                                                           


Thyroid hormone-induced expression of Foxl1 in subepithelial fibroblasts correlates with adult stem cell development during Xenopus intestinal remodeling., Hasebe T, Fujimoto K, Ishizuya-Oka A., Sci Rep. January 1, 2020; 10 (1): 20715.                


Cell type-specific transcriptome analysis unveils secreted signaling molecule genes expressed in apical epithelial cap during appendage regeneration., Okumura A, Hayashi T, Ebisawa M, Yoshimura M, Sasagawa Y, Nikaido I, Umesono Y, Mochii M., Dev Growth Differ. December 1, 2019; 61 (9): 447-456.                


Xenopus slc7a5 is essential for notochord function and eye development., Katada T, Sakurai H., Mech Dev. January 1, 2019; 155 48-59.                


More Than Just a Bandage: Closing the Gap Between Injury and Appendage Regeneration., Kakebeen AD, Wills AE., Front Physiol. January 1, 2019; 10 81.      


Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway., Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E., Mech Dev. January 1, 2019; 156 20-31.                              


Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis., Piprek RP, Damulewicz M, Tassan JP, Kloc M, Kubiak JZ., Dev Genes Evol. January 1, 2019; 229 (2-3): 53-72.        


A dual function of FGF signaling in Xenopus left-right axis formation., Schneider I, Kreis J, Schweickert A, Blum M, Vick P., Development. January 1, 2019; 146 (9):                               


Barhl2 maintains T cell factors as repressors and thereby switches off the Wnt/β-Catenin response driving Spemann organizer formation., Sena E, Rocques N, Borday C, Muhamad Amin HS, Parain K, Sitbon D, Chesneau A, Durand BC., Development. January 1, 2019; 146 (10):                                             


Smoothened stimulation by membrane sterols drives Hedgehog pathway activity., Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A., Nature. January 1, 2019; 571 (7764): 284-288.


Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN)., Tuladhar R, Yarravarapu N, Ma Y, Zhang C, Herbert J, Kim J, Chen C, Lum L., J Biol Chem. January 1, 2019; 294 (16): 6273-6282.              


Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation., Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, Robert J, Robert J, Gilmore N, Gan L, Que J., Dev Cell. January 1, 2019; 51 (6): 675-683.e4.          


Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation., Nasr T, Mancini P, Rankin SA, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, Trisno SL, Cha SW, Wells JM, Kofron MJ, Zorn AM., Dev Cell. January 1, 2019; 51 (6): 665-674.e6.                  


Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate., Kremnyov S, Henningfeld K, Viebahn C, Tsikolia N., Evodevo. January 1, 2018; 9 4.                    


Hyperinnervation improves Xenopus laevis limb regeneration., Mitogawa K, Makanae A, Satoh A., Dev Biol. January 1, 2018; 433 (2): 276-286.                    


Musashi and Plasticity of Xenopus and Axolotl Spinal Cord Ependymal Cells., Chernoff EAG, Sato K, Salfity HVN, Sarria DA, Belecky-Adams T., Front Cell Neurosci. January 1, 2018; 12 45.                          


Gli2 is required for the induction and migration of Xenopus laevis neural crest., Cerrizuela S, Vega-López GA, Palacio MB, Tríbulo C, Aybar MJ, Aybar MJ., Mech Dev. January 1, 2018; 154 219-239.                      


The cytoskeletal protein Zyxin interacts with the zinc-finger transcription factor Zic1 and plays the role of a scaffold for Gli1 and Zic1 interactions during early development of Xenopus laevis., Martynova NY, Parshina EA, Ermolina LV, Zaraisky AG., Biochem Biophys Res Commun. January 1, 2018; 504 (1): 251-256.


Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development., Steimle JD, Rankin SA, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP., Proc Natl Acad Sci U S A. January 1, 2018; 115 (45): E10615-E10624.                                  


WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. January 1, 2018; 145 (23):                 


Structural Basis of Smoothened Activation in Hedgehog Signaling., Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A., Cell. January 1, 2018; 174 (2): 312-324.e16.


Coordinated d-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway., Fink DM, Sun MR, Heyne GW, Everson JL, Chung HM, Park S, Sheets MD, Lipinski RJ., Cell Signal. January 1, 2018; 44 1-9.


A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 1, 2017; 15 (10): e2004045.                                              


High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  


Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing., Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C., Dev Biol. January 1, 2017; 426 (2): 429-441.                    


The Sox transcriptional factors: Functions during intestinal development in vertebrates., Fu L, Shi YB., Semin Cell Dev Biol. January 1, 2017; 63 58-67.        


A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse., Ulmer B, Tingler M, Kurz S, Maerker M, Andre P, Mönch D, Campione M, Deißler K, Lewandoski M, Thumberger T, Schweickert A, Fainsod A, Steinbeißer H, Blum M., Sci Rep. January 1, 2017; 7 43010.                  


Mouth development., Chen J, Jacox LA, Saldanha F, Sive H., Wiley Interdiscip Rev Dev Biol. January 1, 2017; 6 (5):               


Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis., Pitcairn E, Harris H, Epiney J, Pai VP, Lemire JM, Ye B, Shi NQ, Levin M, McLaughlin KA., Commun Integr Biol. January 1, 2017; 10 (3): e1309488.                            


hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus., Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K., Dev Biol. January 1, 2017; 430 (1): 188-201.                      


Folate-dependent methylation of septins governs ciliogenesis during neural tube closure., Toriyama M, Toriyama M, Wallingford JB, Finnell RH., FASEB J. January 1, 2017; 31 (8): 3622-3635.                    


Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear., Zarei S, Zarei K, Fritzsch B, Elliott KL., Dev Neurobiol. January 1, 2017; 77 (12): 1385-1400.                


Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways., Sigg MA, Menchen T, Lee C, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF., Dev Cell. January 1, 2017; 43 (6): 744-762.e11.      


SHH signaling directed by two oral epithelium-specific enhancers controls tooth and oral development., Sagai T, Amano T, Maeno A, Kiyonari H, Seo H, Cho SW, Shiroishi T., Sci Rep. January 1, 2017; 7 (1): 13004.          


Regulation of TRPP3 Channel Function by N-terminal Domain Palmitoylation and Phosphorylation., Zheng W, Yang J, Beauchamp E, Cai R, Hussein S, Hofmann L, Li Q, Flockerzi V, Berthiaume LG, Tang J, Chen XZ., J Biol Chem. December 2, 2016; 291 (49): 25678-25691.


An Evolutionarily Conserved Network Mediates Development of the zona limitans intrathalamica, a Sonic Hedgehog-Secreting Caudal Forebrain Signaling Center., Sena E, Feistel K, Durand BC., J Dev Biol. October 20, 2016; 4 (4):       


Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling., Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A., Cell. August 25, 2016; 166 (5): 1176-1187.e14.


The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery., Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun DA, Pierquin G, Biver A, Wagner K, Malfroot A, Panigrahi I, Franco B, Al-Lami HA, Yeung Y, Choi YJ, null null, Duffourd Y, Faivre L, Rivière JB, Chen J, Liu KJ, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB., Nat Genet. June 1, 2016; 48 (6): 648-56.                              


Localized JNK signaling regulates organ size during development., Willsey HR, Zheng X, Carlos Pastor-Pareja J, Willsey AJ, Beachy PA, Xu T., Elife. March 28, 2016; 5                       


Xenopus Limb bud morphogenesis., Keenan SR, Beck CW., Dev Dyn. March 1, 2016; 245 (3): 233-43.            

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