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Summary Expression Phenotypes Gene Literature (530) GO Terms (16) Nucleotides (154) Proteins (48) Interactants (1740) Wiki
XB--493705

Papers associated with wnt8a (and Disease Ontology)



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The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                

The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway., Predes D, Maia LA, Matias I, Araujo HPM, Soares C, Barros-Aragão FGQ, Oliveira LFS, Reis RR, Amado NG, Simas ABC, Mendes FA, Gomes FCA, Figueiredo CP, Abreu JG., Int J Mol Sci. October 11, 2022; 23 (20):                   

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N, De Robertis EM., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.                          

Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Walentek P., Cells Tissues Organs. January 1, 2022; 211 (6): 736-753.

Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly., Gur M, Bendelac-Kapon L, Shabtai Y, Pillemer G, Fainsod A., Front Cell Dev Biol. January 1, 2022; 10 844619.                        

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis., Kim H, Lee YS, Kim SM, Jang S, Choi H, Lee JW, Kim TD, Kim VN., Dev Cell. April 19, 2021; 56 (8): 1118-1130.e6.                                  

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           

Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Jalvy S, Veschambre P, Fédou S, Rezvani HR, Thézé N, Thiébaud P., Dev Biol. March 15, 2019; 447 (2): 200-213.                                  

WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. November 28, 2018; 145 (23):                 

Ketamine Modulates Zic5 Expression via the Notch Signaling Pathway in Neural Crest Induction., Shi Y, Shi Y, Li J, Chen C, Xia Y, Li Y, Zhang P, Xu Y, Xu Y, Li T, Zhou W, Song W., Front Mol Neurosci. February 7, 2018; 11 9.          

Anosmin-1 is essential for neural crest and cranial placodes formation in Xenopus., Bae CJ, Hong CS, Saint-Jeannet JP., Biochem Biophys Res Commun. January 15, 2018; 495 (3): 2257-2263.        

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

Leftward Flow Determines Laterality in Conjoined Twins., Tisler M, Thumberger T, Schneider I, Schweickert A, Blum M., Curr Biol. February 20, 2017; 27 (4): 543-548.                

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis., Nalesso G, Thomas BL, Sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup AS, Dale L, Schett G, Zwerina J, Eltawil N, Pitzalis C, Dell'Accio F., Ann Rheum Dis. January 1, 2017; 76 (1): 218-226.              

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              

Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF, Predes D, Cerqueira DM, Reis AH, Amado NG, Cayres MC, Kuster RM, Oliveira FL, Mendes FA, Abreu JG., PLoS One. March 16, 2015; 10 (3): e0120919.              

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG, Predes D, Fonseca BF, Cerqueira DM, Reis AH, Dudenhoeffer AC, Borges HL, Mendes FA, Abreu JG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  

The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling., Iwasaki Y, Thomsen GH., Development. October 1, 2014; 141 (19): 3740-51.                                          

Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus., Xu S, Cheng F, Liang J, Wu W, Zhang J., PLoS Biol. January 1, 2012; 10 (3): e1001286.                                    

Paraxial T-box genes, Tbx6 and Tbx1, are required for cranial chondrogenesis and myogenesis., Tazumi S, Yabe S, Uchiyama H., Dev Biol. October 15, 2010; 346 (2): 170-80.                                

APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex., Shimomura Y, Agalliu D, Vonica A, Luria V, Wajid M, Baumer A, Belli S, Petukhova L, Schinzel A, Brivanlou AH, Brivanlou AH, Barres BA, Christiano AM., Nature. April 15, 2010; 464 (7291): 1043-7.      

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity., Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R., J Bone Miner Res. November 1, 2006; 21 (11): 1738-49.              

Emilin1 links TGF-beta maturation to blood pressure homeostasis., Zacchigna L, Vecchione C, Notte A, Cordenonsi M, Dupont S, Maretto S, Cifelli G, Ferrari A, Maffei A, Fabbro C, Braghetta P, Marino G, Selvetella G, Aretini A, Colonnese C, Bettarini U, Russo G, Soligo S, Adorno M, Bonaldo P, Volpin D, Piccolo S, Lembo G, Bressan GM., Cell. March 10, 2006; 124 (5): 929-42.    

Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos., Tao Q, Tao Q, Yokota C, Puck H, Kofron M, Birsoy B, Yan D, Asashima M, Wylie CC, Lin X, Heasman J., Cell. March 25, 2005; 120 (6): 857-71.            

Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis., Zohn IE, Brivanlou AH., Dev Biol. November 1, 2001; 239 (1): 118-31.                    

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