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Summary Expression Phenotypes Gene Literature (27) GO Terms (17) Nucleotides (241) Proteins (61) Interactants (77) Wiki
XB-GENEPAGE-5788003

Papers associated with lig3



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HPF1-dependent PARP activation promotes LIG3-XRCC1-mediated backup pathway of Okazaki fragment ligation., Kumamoto S, Nishiyama A, Chiba Y, Miyashita R, Konishi C, Azuma Y, Nakanishi M., Nucleic Acids Res. May 21, 2021; 49 (9): 5003-5016.            

Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder., Czarny P, Kwiatkowski D, Toma M, Gałecki P, Orzechowska A, Bobińska K, Bielecka-Kowalska A, Szemraj J, Berk M, Anderson G, Śliwiński T., Med Sci Monit. November 20, 2016; 22 4455-4474.

Presequence-Independent Mitochondrial Import of DNA Ligase Facilitates Establishment of Cell Lines with Reduced mtDNA Copy Number., Spadafora D, Kozhukhar N, Alexeyev MF., PLoS One. March 31, 2016; 11 (3): e0152705.              

Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination., Masani S, Han L, Meek K, Yu K., Proc Natl Acad Sci U S A. February 2, 2016; 113 (5): 1261-6.

A computational approach to determine susceptibility to cancer by evaluating the deleterious effect of nsSNP in XRCC1 gene on binding interaction of XRCC1 protein with ligase III., Singh PK, Mistry KN., Gene. January 15, 2016; 576 (1 Pt 1): 141-9.  

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk., Kwiatkowski D, Czarny P, Toma M, Korycinska A, Sowinska K, Galecki P, Bachurska A, Bielecka-Kowalska A, Szemraj J, Maes M, Sliwinski T., Neuropsychobiology. January 1, 2016; 73 (2): 98-107.

Oxidative Stress, DNA Damage and DNA Repair in Female Patients with Diabetes Mellitus Type 2., Grindel A, Guggenberger B, Eichberger L, Pöppelmeyer C, Gschaider M, Tosevska A, Mare G, Briskey D, Brath H, Wagner KH., PLoS One. January 1, 2016; 11 (9): e0162082.  

c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-Activated Leukemias., Muvarak N, Kelley S, Robert C, Baer MR, Perrotti D, Gambacorti-Passerini C, Civin C, Scheibner K, Rassool FV., Mol Cancer Res. April 1, 2015; 13 (4): 699-712.

Polymorphism of the LIG3 gene in keratoconus and Fuchs endothelial corneal dystrophy., Synowiec E, Wojcik KA, Izdebska J, Binczyk E, Szaflik J, Blasiak J, Szaflik JP., Cell Mol Biol (Noisy-le-grand). March 28, 2015; 61 (1): 56-63.

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres., Badie S, Carlos AR, Folio C, Okamoto K, Bouwman P, Jonkers J, Tarsounas M., EMBO J. February 3, 2015; 34 (3): 410-24.              

DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency., Paul-Konietzko K, Thomale J, Arakawa H, Iliakis G., Photochem Photobiol. January 1, 2015; 91 (5): 1173-80.

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair., Abdou I, Poirier GG, Hendzel MJ, Weinfeld M., Nucleic Acids Res. January 1, 2015; 43 (2): 875-92.                      

Escape from telomere-driven crisis is DNA ligase III dependent., Jones RE, Oh S, Grimstead JW, Zimbric J, Roger L, Heppel NH, Ashelford KE, Liddiard K, Hendrickson EA, Baird DM., Cell Rep. August 21, 2014; 8 (4): 1063-76.

Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining., Soni A, Siemann M, Grabos M, Murmann T, Pantelias GE, Iliakis G., Nucleic Acids Res. June 1, 2014; 42 (10): 6380-92.            

DNA ligase I is not essential for mammalian cell viability., Han L, Masani S, Hsieh CL, Yu K., Cell Rep. April 24, 2014; 7 (2): 316-320.      

Intrinsic mitochondrial DNA repair defects in Ataxia Telangiectasia., Sharma NK, Lebedeva M, Thomas T, Kovalenko OA, Stumpf JD, Shadel GS, Santos JH., DNA Repair (Amst). January 1, 2014; 13 22-31.

Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance., Shokolenko IN, Fayzulin RZ, Katyal S, McKinnon PJ, Wilson GL, Alexeyev MF., J Biol Chem. September 13, 2013; 288 (37): 26594-605.

DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates., Paul K, Wang M, Mladenov E, Bencsik-Theilen A, Bednar T, Wu W, Arakawa H, Iliakis G., PLoS One. January 1, 2013; 8 (3): e59505.            

Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells., Arakawa H, Bednar T, Wang M, Paul K, Mladenov E, Bencsik-Theilen AA, Iliakis G., Nucleic Acids Res. March 1, 2012; 40 (6): 2599-610.        

DNA ligase III: a spotty presence in eukaryotes, but an essential function where tested., Simsek D, Jasin M., Cell Cycle. November 1, 2011; 10 (21): 3636-44.

Disconnecting XRCC1 and DNA ligase III., Katyal S, McKinnon PJ., Cell Cycle. July 15, 2011; 10 (14): 2269-75.

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation., Simsek D, Brunet E, Wong SY, Katyal S, Gao Y, McKinnon PJ, Lou J, Zhang L, Li J, Rebar EJ, Gregory PD, Holmes MC, Jasin M., PLoS Genet. June 1, 2011; 7 (6): e1002080.            

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair., Simsek D, Furda A, Gao Y, Artus J, Brunet E, Hadjantonakis AK, Van Houten B, Shuman S, McKinnon PJ, Jasin M., Nature. March 10, 2011; 471 (7337): 245-8.

DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair., Gao Y, Katyal S, Lee Y, Zhao J, Rehg JE, Russell HR, McKinnon PJ., Nature. March 10, 2011; 471 (7337): 240-4.

RETRACTED: Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner., Moser J, Kool H, Giakzidis I, Caldecott K, Mullenders LHF, Fousteri MI., Mol Cell. July 20, 2007; 27 (2): 311-323.

Early embryonic lethality due to targeted inactivation of DNA ligase III., Puebla-Osorio N, Lacey DB, Alt FW, Zhu C., Mol Cell Biol. May 1, 2006; 26 (10): 3935-41.

ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha., Dong Z, Tomkinson AE., Nucleic Acids Res. January 1, 2006; 34 (20): 5721-279.              

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