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Summary Expression Phenotypes Gene Literature (114) GO Terms (7) Nucleotides (42) Proteins (33) Interactants (74) Wiki
XB-GENEPAGE-6043717

Papers associated with p2rx2



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Dopamine and 5-hydroxytryptamine selectively potentiate neuronal type ATP receptor channels., Nakazawa K, Ohno Y., Eur J Pharmacol. January 18, 1996; 296 (1): 119-22.


Full sensitivity of P2X2 purinoceptor to ATP revealed by changing extracellular pH., King BF, Ziganshina LE, Pintor J, Burnstock G., Br J Pharmacol. April 1, 1996; 117 (7): 1371-3.


Selectivity and activity of adenine dinucleotides at recombinant P2X2 and P2Y1 purinoceptors., Pintor J, King BF, Miras-Portugal MT, Burnstock G., Br J Pharmacol. November 1, 1996; 119 (5): 1006-12.


Domains of P2X receptors involved in desensitization., Werner P, Seward EP, Buell GN, North RA., Proc Natl Acad Sci U S A. December 24, 1996; 93 (26): 15485-90.


Potentiation of ATP-responses at a recombinant P2x2 receptor by neurotransmitters and related substances., Wildman SS, King BF, Burnstock G., Br J Pharmacol. January 1, 1997; 120 (2): 221-4.


Neuropharmacology: a part for purines in pattern generation., Halliday FC, Gibb AJ., Curr Biol. January 1, 1997; 7 (1): R47-9.


Desensitization of the P2X(2) receptor controlled by alternative splicing., Brändle U, Spielmanns P, Osteroth R, Sim J, Surprenant A, Buell G, Ruppersberg JP, Plinkert PK, Zenner HP, Glowatzki E., FEBS Lett. March 10, 1997; 404 (2-3): 294-8.


Effects of neuroamines and divalent cations on cloned and mutated ATP-gated channels., Nakazawa K, Ohno Y., Eur J Pharmacol. April 23, 1997; 325 (1): 101-8.


Potent inhibition by trivalent cations of ATP-gated channels., Nakazawa K, Liu M, Inoue K, Ohno Y., Eur J Pharmacol. May 1, 1997; 325 (2-3): 237-43.


Localization and functional expression of splice variants of the P2X2 receptor., Simon J, Kidd EJ, Smith FM, Chessell IP, Murrell-Lagnado R, Humphrey PP, Barnard EA., Mol Pharmacol. August 1, 1997; 52 (2): 237-48.


Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor., King BF, Wildman SS, Ziganshina LE, Pintor J, Burnstock G., Br J Pharmacol. August 1, 1997; 121 (7): 1445-53.


Mechanically and ATP-induced currents of mouse outer hair cells are independent and differentially blocked by d-tubocurarine., Glowatzki E, Ruppersberg JP, Zenner HP, Rüsch A., Neuropharmacology. September 1, 1997; 36 (9): 1269-75.


pH dependence of facilitation by neurotransmitters and divalent cations of P2X2 purinoceptor/channels., Nakazawa K, Liu M, Inoue K, Ohno Y., Eur J Pharmacol. October 22, 1997; 337 (2-3): 309-14.


Zn2+ modulation of ATP-responses at recombinant P2X2 receptors and its dependence on extracellular pH., Wildman SS, King BF, Burnstock G., Br J Pharmacol. March 1, 1998; 123 (6): 1214-20.


Two mechanisms for inward rectification of current flow through the purinoceptor P2X2 class of ATP-gated channels., Zhou Z, Hume RI., J Physiol. March 1, 1998; 507 ( Pt 2) 353-64.


An aspartic acid residue near the second transmembrane segment of ATP receptor/channel regulates agonist sensitivity., Nakazawa K, Ohno Y, Inoue K., Biochem Biophys Res Commun. March 17, 1998; 244 (2): 599-603.


An asparagine residue regulating conductance through P2X2 receptor/channels., Nakazawa K, Inoue K, Ohno Y., Eur J Pharmacol. April 17, 1998; 347 (1): 141-4.


Membrane topology of an ATP-gated ion channel (P2X receptor)., Newbolt A, Stoop R, Virginio C, Surprenant A, North RA, Buell G, Rassendren F., J Biol Chem. June 12, 1998; 273 (24): 15177-82.


A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors., Jacobson KA, Kim YC, Wildman SS, Mohanram A, Harden TK, Boyer JL, King BF, Burnstock G., J Med Chem. June 18, 1998; 41 (13): 2201-6.


Identification of a site that modifies desensitization of P2X2 receptors., Zhou Z, Monsma LR, Hume RI., Biochem Biophys Res Commun. November 27, 1998; 252 (3): 541-5.


Antagonistic properties of the suramin analogue NF023 at heterologously expressed P2X receptors., Soto F, Lambrecht G, Nickel P, Stühmer W, Busch AE., Neuropharmacology. January 1, 1999; 38 (1): 141-9.


Selectivity of diadenosine polyphosphates for rat P2X receptor subunits., Wildman SS, Brown SG, King BF, Burnstock G., Eur J Pharmacol. February 12, 1999; 367 (1): 119-23.


Block and unblock by imipramine of cloned and mutated P2X2 receptor/channel expressed in Xenopus oocytes., Nakazawa K, Inoue K, Ohno Y., Neurosci Lett. April 2, 1999; 264 (1-3): 93-6.


Neighboring glycine residues are essential for P2X2 receptor/channel function., Nakazawa K, Ohno Y., Eur J Pharmacol. April 16, 1999; 370 (3): R5-6.


Differential modulation by copper and zinc of P2X2 and P2X4 receptor function., Xiong K, Peoples RW, Montgomery JP, Chiang Y, Stewart RR, Weight FF, Li C., J Neurophysiol. May 1, 1999; 81 (5): 2088-94.


Single channel properties of P2X2 purinoceptors., Ding S, Sachs F., J Gen Physiol. May 1, 1999; 113 (5): 695-720.                                


Identification of amino acids within the P2X2 receptor C-terminus that regulate desensitization., Smith FM, Humphrey PP, Murrell-Lagnado RD., J Physiol. October 1, 1999; 520 Pt 1 91-9.


5-Hydroxytryptamine inhibits P2X2 receptor channel pore mutants., Nakazawa K, Ohno Y., Cell Mol Neurobiol. October 1, 1999; 19 (5): 665-9.


Contribution of individual subunits to the multimeric P2X(2) receptor: estimates based on methanethiosulfonate block at T336C., Stoop R, Thomas S, Rassendren F, Kawashima E, Buell G, Surprenant A, North RA., Mol Pharmacol. November 1, 1999; 56 (5): 973-81.


Molecular and functional characterization of human P2X(2) receptors., Lynch KJ, Touma E, Niforatos W, Kage KL, Burgard EC, van Biesen T, Kowaluk EA, Jarvis MF., Mol Pharmacol. December 1, 1999; 56 (6): 1171-81.


A protein kinase C site highly conserved in P2X subunits controls the desensitization kinetics of P2X(2) ATP-gated channels., Boué-Grabot E, Archambault V, Séguéla P., J Biol Chem. April 7, 2000; 275 (14): 10190-5.


Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes., King BF, Townsend-Nicholson A, Wildman SS, Thomas T, Spyer KM, Burnstock G., J Neurosci. July 1, 2000; 20 (13): 4871-7.


In search of selective P2 receptor ligands: interaction of dihydropyridine derivatives at recombinant rat P2X(2) receptors., Jacobson KA, Kim YC, King BF., J Auton Nerv Syst. July 3, 2000; 81 (1-3): 152-7.


State-dependent cross-inhibition between transmitter-gated cation channels., Khakh BS, Zhou X, Sydes J, Galligan JJ, Lester HA., Nature. July 27, 2000; 406 (6794): 405-10.


Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors., Kim YC, Brown SG, Harden TK, Boyer JL, Dubyak G, King BF, Burnstock G, Jacobson KA., J Med Chem. February 1, 2001; 44 (3): 340-9.


Coexpression of P2X(3) and P2X(2) receptor subunits in varying amounts generates heterogeneous populations of P2X receptors that evoke a spectrum of agonist responses comparable to that seen in sensory neurons., Liu M, King BF, Dunn PM, Rong W, Townsend-Nicholson A, Burnstock G., J Pharmacol Exp Ther. March 1, 2001; 296 (3): 1043-50.


Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X2-green fluorescent protein receptors., Khakh BS, Smith WB, Chiu CS, Ju D, Davidson N, Lester HA., Proc Natl Acad Sci U S A. April 24, 2001; 98 (9): 5288-93.


Inflammatory mediators potentiate ATP-gated channels through the P2X(3) subunit., Paukert M, Osteroth R, Geisler HS, Brandle U, Glowatzki E, Ruppersberg JP, Gründer S., J Biol Chem. June 15, 2001; 276 (24): 21077-82.


Single amino acid residue influences the distribution pattern of an inwardly rectifying potassium channel in polarized cells., Wild K, Paysan J., Cell Tissue Res. January 1, 2002; 307 (1): 47-55.


The role of histidine residues in modulation of the rat P2X(2) purinoceptor by zinc and pH., Clyne JD, LaPointe LD, Hume RI., J Physiol. March 1, 2002; 539 (Pt 2): 347-59.


Mutational analysis of the conserved cysteines of the rat P2X2 purinoceptor., Clyne JD, Wang LF, Hume RI., J Neurosci. May 15, 2002; 22 (10): 3873-80.


A highly conserved tryptophane residue indispensable for cloned rat neuronal P2X receptor activation., Nakazawa K, Ojima H, Ohno Y., Neurosci Lett. May 17, 2002; 324 (2): 141-4.


Ethanol sensitivity in ATP-gated P2X receptors is subunit dependent., Davies DL, Machu TK, Guo Y, Alkana RL., Alcohol Clin Exp Res. June 1, 2002; 26 (6): 773-8.


Control of P2X(2) channel permeability by the cytosolic domain., Eickhorst AN, Berson A, Cockayne D, Lester HA, Khakh BS., J Gen Physiol. August 1, 2002; 120 (2): 119-31.                  


Size of side-chain at channel pore mouth affects Ca(2+) block of P2X(2) receptor., Nakazawa K, Sawa H, Ojima H, Ishii-Nozawa R, Takeuchi K, Ohno Y., Eur J Pharmacol. August 9, 2002; 449 (3): 207-11.


Evidence for non-independent gating of P2X2 receptors expressed in Xenopus oocytes., Ding S, Sachs F., BMC Neurosci. November 6, 2002; 3 17.          


Heteromultimerization modulates P2X receptor functions through participating extracellular and C-terminal subdomains., Koshimizu TA, Ueno S, Tanoue A, Yanagihara N, Stojilkovic SS, Tsujimoto G., J Biol Chem. December 6, 2002; 277 (49): 46891-9.


Allosteric modulation of native cochlear P2X receptors: insights from comparison with recombinant P2X2 receptors., Kanjhan R, Raybould NP, Jagger DJ, Greenwood D, Housley GD., Audiol Neurootol. January 1, 2003; 8 (3): 115-28.


Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels., Boué-Grabot E, Barajas-López C, Chakfe Y, Blais D, Bélanger D, Emerit MB, Séguéla P., J Neurosci. February 15, 2003; 23 (4): 1246-53.


Expression level dependent changes in the properties of P2X2 receptors., Clyne JD, Brown TC, Hume RI., Neuropharmacology. March 1, 2003; 44 (3): 403-12.

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