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Summary Expression Phenotypes Gene Literature (44) GO Terms (21) Nucleotides (54) Proteins (44) Interactants (42) Wiki
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Papers associated with abcc9



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Role of the C-terminus of SUR in the differential regulation of β-cell and cardiac KATP channels by MgADP and metabolism., Vedovato N, Rorsman O, Hennis K, Ashcroft FM, Proks P., J Physiol. December 1, 2018; 596 (24): 6205-6217.            

Sensitivity of KATP channels to cellular metabolic disorders and the underlying structural basis., Li CG, Cui WY, Wang H., Acta Pharmacol Sin. January 1, 2016; 37 (1): 134-42.        

Kir6.2 activation by sulfonylurea receptors: a different mechanism of action for SUR1 and SUR2A subunits via the same residues., Principalli MA, Dupuis JP, Moreau CJ, Vivaudou M, Revilloud J., Physiol Rep. September 1, 2015; 3 (9):         

Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study., Proks P, de Wet H, Ashcroft FM., J Gen Physiol. November 1, 2014; 144 (5): 469-86.                  

Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development., Liu Z, Li W, Ma X, Ding N, Spallotta F, Southon E, Tessarollo L, Gaetano C, Mukouyama YS, Thiele CJ., J Biol Chem. October 24, 2014; 289 (43): 29801-16.

The unusual stoichiometry of ADP activation of the KATP channel., Hosy E, Vivaudou M., Front Physiol. January 28, 2014; 5 11.        

Neurally Derived Tissues in Xenopus laevis Embryos Exhibit a Consistent Bioelectrical Left-Right Asymmetry., Pai VP, Vandenberg LN, Blackiston D, Levin M., Stem Cells Int. January 1, 2012; 2012 353491.          

The ATP-sensitive K(+)-channel (K(ATP)) controls early left-right patterning in Xenopus and chick embryos., Aw S, Koster JC, Pearson W, Nichols CG, Shi NQ, Carneiro K, Levin M., Dev Biol. October 1, 2010; 346 (1): 39-53.        

Targeting hypertension with a new adenosine triphosphate-sensitive potassium channel opener iptakalim., Pan Z, Huang J, Cui W, Long C, Zhang Y, Wang H., J Cardiovasc Pharmacol. September 1, 2010; 56 (3): 215-28.

Impact of disease-causing SUR1 mutations on the KATP channel subunit interface probed with a rhodamine protection assay., Hosy E, Dupuis JP, Vivaudou M., J Biol Chem. January 29, 2010; 285 (5): 3084-91.

Coassembly of different sulfonylurea receptor subtypes extends the phenotypic diversity of ATP-sensitive potassium (KATP) channels., Wheeler A, Wang C, Yang K, Fang K, Davis K, Styer AM, Mirshahi U, Moreau C, Revilloud J, Vivaudou M, Liu S, Mirshahi T, Chan KW., Mol Pharmacol. November 1, 2008; 74 (5): 1333-44.

Three C-terminal residues from the sulphonylurea receptor contribute to the functional coupling between the K(ATP) channel subunits SUR2A and Kir6.2., Dupuis JP, Revilloud J, Moreau CJ, Vivaudou M., J Physiol. July 1, 2008; 586 (13): 3075-85.

Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition., Chan KW, Wheeler A, Csanády L., J Gen Physiol. January 1, 2008; 131 (1): 43-58.                    

A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit., Tammaro P, Ashcroft FM., J Physiol. November 1, 2007; 584 (Pt 3): 743-53.

The Kir6.2-F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits., Tammaro P, Ashcroft F., J Physiol. June 15, 2007; 581 (Pt 3): 1259-69.

Electrophysiological and pharmacological characterization of the K(ATP) channel involved in the K+-current responses to FSH and adenosine in the follicular cells of Xenopus oocyte., Fujita R, Kimura S, Kawasaki S, Watanabe S, Watanabe N, Hirano H, Matsumoto M, Sasaki K., J Physiol Sci. February 1, 2007; 57 (1): 51-61.

The N-terminal transmembrane domain (TMD0) and a cytosolic linker (L0) of sulphonylurea receptor define the unique intrinsic gating of KATP channels., Fang K, Csanády L, Chan KW., J Physiol. October 15, 2006; 576 (Pt 2): 379-89.

Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels., Tammaro P, Proks P, Ashcroft FM., J Physiol. February 15, 2006; 571 (Pt 1): 3-14.

Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators., Hambrock A, Kayar T, Stumpp D, Osswald H., Diabetes. December 1, 2004; 53 Suppl 3 S128-34.

Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes., Lim JG, Lee HY, Yun JE, Kim SP, Park JW, Suh SI, Jang BC, Cho CH, Bae JH, Kim SS, Han J, Park MJ, Song DK., Biochem Pharmacol. September 1, 2004; 68 (5): 901-10.

Zinc is both an intracellular and extracellular regulator of KATP channel function., Prost AL, Bloc A, Hussy N, Derand R, Vivaudou M., J Physiol. August 15, 2004; 559 (Pt 1): 157-67.

Inhibition of ATP-sensitive K+ channels by substituted benzo[c]quinolizinium CFTR activators., Prost A, Dérand R, Gros L, Becq F, Vivaudou M., Biochem Pharmacol. August 1, 2003; 66 (3): 425-30.

Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides., Reimann F, Dabrowski M, Jones P, Gribble FM, Ashcroft FM., J Physiol. February 15, 2003; 547 (Pt 1): 159-68.

Differential selectivity of insulin secretagogues: mechanisms, clinical implications, and drug interactions., Gribble FM, Reimann F., J Diabetes Complications. January 1, 2003; 17 (2 Suppl): 11-5.

K(ATP) channel activity is required for hatching in Xenopus embryos., Cheng SM, Chen I, Levin M., Dev Dyn. December 1, 2002; 225 (4): 588-91.        

Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding., Matsuo M, Dabrowski M, Ueda K, Ashcroft FM., EMBO J. August 15, 2002; 21 (16): 4250-8.

The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener., Dabrowski M, Ashcroft FM, Ashfield R, Lebrun P, Pirotte B, Egebjerg J, Bondo Hansen J, Wahl P., Diabetes. June 1, 2002; 51 (6): 1896-906.

Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel., Brochiero E, Wallendorf B, Gagnon D, Laprade R, Lapointe JY., Am J Physiol Renal Physiol. February 1, 2002; 282 (2): F289-300.

Amiloride derivatives are potent blockers of KATP channels., Bollensdorff C, Zimmer T, Benndorf K., Naunyn Schmiedebergs Arch Pharmacol. October 1, 2001; 364 (4): 351-8.

Structural basis for the interference between nicorandil and sulfonylurea action., Reimann F, Ashcroft FM, Gribble FM., Diabetes. October 1, 2001; 50 (10): 2253-9.

Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channels., Dabrowski M, Wahl P, Holmes WE, Ashcroft FM., Diabetologia. June 1, 2001; 44 (6): 747-56.

Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels., Song DK, Ashcroft FM., Br J Pharmacol. May 1, 2001; 133 (1): 193-9.

Phospholipids as modulators of K(ATP) channels: distinct mechanisms for control of sensitivity to sulphonylureas, K(+) channel openers, and ATP., Krauter T, Ruppersberg JP, Baukrowitz T., Mol Pharmacol. May 1, 2001; 59 (5): 1086-93.

Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel., Reimann F, Proks P, Ashcroft FM., Br J Pharmacol. April 1, 2001; 132 (7): 1542-8.

Interaction of stilbene disulphonates with cloned K(ATP) channels., Proks P, Jones P, Ashcroft FM., Br J Pharmacol. March 1, 2001; 132 (5): 973-82.

Differential response of K(ATP) channels containing SUR2A or SUR2B subunits to nucleotides and pinacidil., Reimann F, Gribble FM, Ashcroft FM., Mol Pharmacol. December 1, 2000; 58 (6): 1318-25.

Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A., Gribble FM, Reimann F, Ashfield R, Ashcroft FM., Mol Pharmacol. June 1, 2000; 57 (6): 1256-61.

Rat homolog of sulfonylurea receptor 2B determines glibenclamide sensitivity of ROMK2 in Xenopus laevis oocyte., Tanemoto M, Vanoye CG, Dong K, Welch R, Abe T, Hebert SC, Xu JZ., Am J Physiol Renal Physiol. April 1, 2000; 278 (4): F659-66.

Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP., D'hahan N, Moreau C, Prost AL, Jacquet H, Alekseev AE, Terzic A, Vivaudou M., Proc Natl Acad Sci U S A. October 12, 1999; 96 (21): 12162-7.

Interaction of vanadate with the cloned beta cell K(ATP) channel., Proks P, Ashfield R, Ashcroft FM., J Biol Chem. September 3, 1999; 274 (36): 25393-7.

A transmembrane domain of the sulfonylurea receptor mediates activation of ATP-sensitive K(+) channels by K(+) channel openers., D'hahan N, Jacquet H, Moreau C, Catty P, Vivaudou M., Mol Pharmacol. August 1, 1999; 56 (2): 308-15.

Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide., Gribble FM, Ashcroft FM., Diabetologia. July 1, 1999; 42 (7): 845-8.

Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel., Ashfield R, Gribble FM, Ashcroft SJ, Ashcroft FM., Diabetes. June 1, 1999; 48 (6): 1341-7.

Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels., Gribble FM, Tucker SJ, Seino S, Ashcroft FM., Diabetes. September 1, 1998; 47 (9): 1412-8.

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