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Summary Expression Phenotypes Gene Literature (41) GO Terms (4) Nucleotides (59) Proteins (11) Interactants (256) Wiki
XB-GENEPAGE-855943

Papers associated with h2ax



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Mebendazole preferentially inhibits cilia formation and exerts anticancer activity by synergistically augmenting DNA damage., Hong J, Kwon KY, Jang DG, Kwon T, Yoon H, Park TJ., Biomed Pharmacother. March 20, 2024; 174 116434.                              

The molecular mechanisms underlying the regeneration process in the earthworm, Perionyx excavatus exhibit indications of apoptosis-induced compensatory proliferation (AICP)., Rajagopalan K, Christyraj JDS, Chelladurai KS, Christyraj JRSS, Das P, Roy A, Vrushali C, Chemmet NSM., In Vitro Cell Dev Biol Anim. March 1, 2024; 60 (3): 222-235.

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair., Zhu S, Paydar M, Wang F, Li Y, Wang L, Barrette B, Bessho T, Kwok BH, Peng A., Elife. January 17, 2020; 9                                                         

Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements., Deng L, Wu RA, Sonneville R, Kochenova OV, Labib K, Pellman D, Walter JC., Mol Cell. March 7, 2019; 73 (5): 915-929.e6.                              

Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund-Thomson syndrome., Yokoyama H, Moreno-Andres D, Astrinidis SA, Hao Y, Weberruss M, Schellhaus AK, Lue H, Haramoto Y, Gruss OJ, Antonin W., Life Sci Alliance. February 4, 2019; 2 (1):                                   

Nuclear ARP2/3 drives DNA break clustering for homology-directed repair., Schrank BR, Aparicio T, Li Y, Chang W, Chait BT, Gundersen GG, Gottesman ME, Gautier J., Nature. July 1, 2018; 559 (7712): 61-66.                              

Paternal chromosome loss and metabolic crisis contribute to hybrid inviability in Xenopus., Gibeaux R, Acker R, Kitaoka M, Georgiou G, van Kruijsbergen I, Ford B, Marcotte EM, Nomura DK, Kwon T, Veenstra GJC, Heald R., Nature. January 18, 2018; 553 (7688): 337-341.      

Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining., Zhu S, Fisher LA, Bessho T, Peng A., Nucleic Acids Res. October 13, 2017; 45 (18): 10583-10594.            

Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2., Dankert JF, Rona G, Clijsters L, Geter P, Skaar JR, Bermudez-Hernandez K, Sassani E, Fenyö D, Ueberheide B, Schneider R, Pagano M., Mol Cell. November 3, 2016; 64 (3): 507-519.

CRN13 candidate effectors from plant and animal eukaryotic pathogens are DNA-binding proteins which trigger host DNA damage response., Ramirez-Garcés D, Camborde L, Pel MJ, Jauneau A, Martinez Y, Néant I, Leclerc C, Moreau M, Dumas B, Gaulin E., New Phytol. April 1, 2016; 210 (2): 602-17.

Sexually dimorphic expression of Dmrt1 and γH2AX in germ stem cells during gonadal development in Xenopus laevis., Fujitani K, Otomo A, Wada M, Takamatsu N, Ito M., FEBS Open Bio. February 26, 2016; 6 (4): 276-84.                        

YAP controls retinal stem cell DNA replication timing and genomic stability., Cabochette P, Vega-Lopez G, Bitard J, Parain K, Chemouny R, Masson C, Borday C, Hedderich M, Henningfeld KA, Locker M, Bronchain O, Perron M., Elife. September 22, 2015; 4 e08488.                                    

Reconstitution of mitotic chromatids with a minimum set of purified factors., Shintomi K, Takahashi TS, Hirano T., Nat Cell Biol. August 1, 2015; 17 (8): 1014-23.

Downregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cells., Krishnamurthy N, Liu L, Xiong X, Zhang J, Montano MM., Cancer Biol Ther. January 1, 2015; 16 (4): 518-27.

Initiation and maintenance of pluripotency gene expression in the absence of cohesin., Lavagnolli T, Gupta P, Hörmanseder E, Mira-Bontenbal H, Dharmalingam G, Carroll T, Gurdon JB, Fisher AG, Merkenschlager M., Genes Dev. January 1, 2015; 29 (1): 23-38.              

Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development., Wang WL, Anderson LC, Nicklay JJ, Chen H, Gamble MJ, Shabanowitz J, Hunt DF, Shechter D., Epigenetics Chromatin. September 6, 2014; 7 22.                

Proteomic analysis of fibroblastema formation in regenerating hind limbs of Xenopus laevis froglets and comparison to axolotl., Rao N, Song F, Jhamb D, Wang M, Milner DJ, Price NM, Belecky-Adams TL, Palakal MJ, Cameron JA, Li B, Chen X, Stocum DL., BMC Dev Biol. July 25, 2014; 14 32.                        

Transcriptomic profiling in Silurana tropicalis testes exposed to finasteride., Bissegger S, Martyniuk CJ, Langlois VS., Gen Comp Endocrinol. July 1, 2014; 203 137-45.

Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity., Ho MC, Wilczek C, Bonanno JB, Xing L, Seznec J, Matsui T, Carter LG, Onikubo T, Kumar PR, Chan MK, Brenowitz M, Cheng RH, Reimer U, Almo SC, Shechter D., PLoS One. January 1, 2013; 8 (2): e57008.              

DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates., Paul K, Wang M, Mladenov E, Bencsik-Theilen A, Bednar T, Wu W, Arakawa H, Iliakis G., PLoS One. January 1, 2013; 8 (3): e59505.            

Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation., Neumayer G, Helfricht A, Shim SY, Le HT, Lundin C, Belzil C, Chansard M, Yu Y, Lees-Miller SP, Gruss OJ, van Attikum H, Helleday T, Nguyen MD., J Biol Chem. December 7, 2012; 287 (50): 42206-22.

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks., Hashimoto Y, Puddu F, Costanzo V., Nat Struct Mol Biol. December 4, 2011; 19 (1): 17-24.          

Uracil DNA N-glycosylase promotes assembly of human centromere protein A., Zeitlin SG, Chapados BR, Baker NM, Tai C, Slupphaug G, Wang JY., PLoS One. March 2, 2011; 6 (3): e17151.                        

Histone XH2AX is required for Xenopus anterior neural development: critical role of threonine 16 phosphorylation., Lee SY, Lau AT, Jeong CH, Shim JH, Kim HG, Kim J, Bode AM, Dong Z., J Biol Chem. September 17, 2010; 285 (38): 29525-34.                  

Treslin collaborates with TopBP1 in triggering the initiation of DNA replication., Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Cell. February 5, 2010; 140 (3): 349-59.                        

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors., Landais I, Hiddingh S, McCarroll M, Yang C, Sun A, Turker MS, Snyder JP, Hoatlin ME., Mol Cancer. December 31, 2009; 8 133.                

Replication initiation complex formation in the absence of nuclear function in Xenopus., Krasinska L, Fisher D., Nucleic Acids Res. April 1, 2009; 37 (7): 2238-48.            

A distinct H2A.X isoform is enriched in Xenopus laevis eggs and early embryos and is phosphorylated in the absence of a checkpoint., Shechter D, Chitta RK, Xiao A, Shabanowitz J, Hunt DF, Allis CD., Proc Natl Acad Sci U S A. January 20, 2009; 106 (3): 749-54.

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity., Jazayeri A, Balestrini A, Garner E, Haber JE, Costanzo V., EMBO J. July 23, 2008; 27 (14): 1953-62.              

NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells., Qi W, Shakalya K, Stejskal A, Goldman A, Beeck S, Cooke L, Mahadevan D., Oncogene. July 10, 2008; 27 (30): 4210-20.

Undamaged DNA transmits and enhances DNA damage checkpoint signals in early embryos., Peng A, Lewellyn AL, Maller JL., Mol Cell Biol. October 1, 2007; 27 (19): 6852-62.

Non-transcriptional control of DNA replication by c-Myc., Dominguez-Sola D, Ying CY, Grandori C, Ruggiero L, Chen B, Li M, Galloway DA, Gu W, Gautier J, Dalla-Favera R., Nature. July 26, 2007; 448 (7152): 445-51.      

Differential recruitment of DNA Ligase I and III to DNA repair sites., Mortusewicz O, Rothbauer U, Cardoso MC, Leonhardt H., Nucleic Acids Res. January 1, 2006; 34 (12): 3523-32.                  

Human TopBP1 ensures genome integrity during normal S phase., Kim JE, McAvoy SA, Smith DI, Chen J., Mol Cell Biol. December 1, 2005; 25 (24): 10907-15.

A hypophosphorylated form of RPA34 is a specific component of pre-replication centers., Françon P, Lemaître JM, Dreyer C, Maiorano D, Cuvier O, Méchali M., J Cell Sci. October 1, 2004; 117 (Pt 21): 4909-20.                      

Mre11 assembles linear DNA fragments into DNA damage signaling complexes., Costanzo V, Paull T, Gottesman M, Gautier J., PLoS Biol. May 1, 2004; 2 (5): E110.          

Focus-formation of replication protein A, activation of checkpoint system and DNA repair synthesis induced by DNA double-strand breaks in Xenopus egg extract., Kobayashi T, Tada S, Tsuyama T, Murofushi H, Seki M, Enomoto T., J Cell Sci. August 1, 2002; 115 (Pt 15): 3159-69.

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication., Costanzo V, Robertson K, Bibikova M, Kim E, Grieco D, Gottesman M, Carroll D, Gautier J., Mol Cell. July 1, 2001; 8 (1): 137-47.

Megabase chromatin domains involved in DNA double-strand breaks in vivo., Rogakou EP, Boon C, Redon C, Bonner WM., J Cell Biol. September 6, 1999; 146 (5): 905-16.              

Remodeling sperm chromatin in Xenopus laevis egg extracts: the role of core histone phosphorylation and linker histone B4 in chromatin assembly., Dimitrov S, Dasso MC, Wolffe AP., J Cell Biol. August 1, 1994; 126 (3): 591-601.

DNA-dependent phosphorylation of histone H2A.X during nucleosome assembly in Xenopus laevis oocytes: involvement of protein phosphorylation in nucleosome spacing., Kleinschmidt JA, Steinbeisser H., EMBO J. October 1, 1991; 10 (10): 3043-50.

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