Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (42) GO Terms (11) Nucleotides (122) Proteins (47) Interactants (244) Wiki
XB-GENEPAGE-943035

Papers associated with nbn



???displayGene.coCitedPapers???
1 ???displayGene.morpholinoPapers???

???pagination.result.count???

???pagination.result.page??? 1

Sort Newest To Oldest Sort Oldest To Newest

Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts., Tatsukawa K, Sakamoto R, Kawasoe Y, Kubota Y, Tsurimoto T, Takahashi TS, Ohashi E., Nucleic Acids Res. April 12, 2024; 52 (6): 3146-3163.                  

POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps., Mann A, Ramirez-Otero MA, De Antoni A, Hanthi YW, Sannino V, Baldi G, Falbo L, Schrempf A, Bernardo S, Loizou J, Costanzo V., Mol Cell. November 17, 2022; 82 (22): 4218-4231.e8.                              

MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks., Montales K, Ruis K, Lindsay H, Michael WM., PLoS One. August 2, 2022; 17 (8): e0271905.                

ZC3HC1 Is a Novel Inherent Component of the Nuclear Basket, Resident in a State of Reciprocal Dependence with TPR., Gunkel P, Iino H, Krull S, Cordes VC., Cells. July 30, 2021; 10 (8):               

Conservation and divergence of protein pathways in the vertebrate heart., Federspiel JD, Tandon P, Wilczewski CM, Wasson L, Herring LE, Venkatesh SS, Cristea IM, Conlon FL., PLoS Biol. September 6, 2019; 17 (9): e3000437.                                                    

Dna2 initiates resection at clean DNA double-strand breaks., Paudyal SC, Li S, Yan H, Hunter T, You Z., Nucleic Acids Res. November 16, 2017; 45 (20): 11766-11781.            

Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining., Zhu S, Fisher LA, Bessho T, Peng A., Nucleic Acids Res. October 13, 2017; 45 (18): 10583-10594.            

Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses., Choi SH, Yoo HY., Biochem Biophys Res Commun. October 7, 2016; 479 (1): 5-11.

Xenopus Mcm10 is a CDK-substrate required for replication fork stability., Chadha GS, Gambus A, Gillespie PJ, Blow JJ., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.            

MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex., Lee KY, Im JS, Shibata E, Park J, Handa N, Kowalczykowski SC, Dutta A., Nat Commun. July 28, 2015; 6 7744.              

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA, Hardwick LJ, Papkovskaia TD, Thiele CJ, Philpott A., Dis Model Mech. May 1, 2015; 8 (5): 429-41.                

Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators., Zimmerman SS, Khatri A, Garnier-Amblard EC, Mullasseril P, Kurtkaya NL, Gyoneva S, Hansen KB, Traynelis SF, Liotta DC., J Med Chem. March 27, 2014; 57 (6): 2334-56.                

Construction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division., Grob A, McStay B., Cell Cycle. January 1, 2014; 13 (16): 2501-8.

PCNA promotes processive DNA end resection by Exo1., Chen X, Paudyal SC, Chin RI, You Z., Nucleic Acids Res. November 1, 2013; 41 (20): 9325-38.              

The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks., Lee J, Dunphy WG., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.          

A role for the MRN complex in ATR activation via TOPBP1 recruitment., Duursma AM, Driscoll R, Elias JE, Cimprich KA., Mol Cell. April 11, 2013; 50 (1): 116-22.

The MRN-CtIP pathway is required for metaphase chromosome alignment., Rozier L, Guo Y, Peterson S, Sato M, Baer R, Gautier J, Mao Y., Mol Cell. March 28, 2013; 49 (6): 1097-107.

Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC., Reschen RF, Colombie N, Wheatley L, Dobbelaere J, St Johnston D, Ohkura H, Raff JW., Biol Open. May 15, 2012; 1 (5): 422-9.          

Analysis of MRE11's function in the 5'-->3' processing of DNA double-strand breaks., Liao S, Guay C, Toczylowski T, Yan H., Nucleic Acids Res. May 1, 2012; 40 (10): 4496-506.                

Time-dependent predominance of nonhomologous DNA end-joining pathways during embryonic development in mice., Chiruvella KK, Sebastian R, Sharma S, Karande AA, Choudhary B, Raghavan SC., J Mol Biol. March 30, 2012; 417 (3): 197-211.

Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts., Kumar S, Yoo HY, Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Cell Cycle. March 15, 2012; 11 (6): 1183-94.

Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm., Pieper M, Ahrens K, Rink E, Peter A, Schlosser G., Development. March 1, 2012; 139 (6): 1175-87.                    

Essential roles of Xenopus TRF2 in telomere end protection and replication., Muraki K, Nabetani A, Nishiyama A, Ishikawa F., Genes Cells. June 1, 2011; 16 (6): 728-39.

CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts., Ramírez-Lugo JS, Yoo HY, Yoon SJ, Dunphy WG., Cell Cycle. February 1, 2011; 10 (3): 469-80.

Amino acid residues constituting the agonist binding site of the human P2X3 receptor., Bodnar M, Wang H, Riedel T, Hintze S, Kato E, Fallah G, Gröger-Arndt H, Giniatullin R, Grohmann M, Hausmann R, Schmalzing G, Illes P, Rubini P., J Biol Chem. January 28, 2011; 286 (4): 2739-49.

Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM., Wawrousek KE, Fortini BK, Polaczek P, Chen L, Liu Q, Dunphy WG, Campbell JL., Cell Cycle. March 15, 2010; 9 (6): 1156-66.

The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis., Taylor EM, Cecillon SM, Bonis A, Chapman JR, Povirk LF, Lindsay HD., Nucleic Acids Res. January 1, 2010; 38 (2): 441-54.        

CtIP links DNA double-strand break sensing to resection., You Z, Shi LZ, Zhu Q, Wu P, Zhang YW, Basilio A, Tonnu N, Verma IM, Berns MW, Hunter T., Mol Cell. December 25, 2009; 36 (6): 954-69.

PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin., Di Virgilio M, Ying CY, Gautier J., DNA Repair (Amst). November 2, 2009; 8 (11): 1311-20.

The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM., Yoo HY, Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Mol Biol Cell. May 1, 2009; 20 (9): 2351-60.

Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites., Xu C, Wu L, Cui G, Botuyan MV, Chen J, Mer G., J Mol Biol. August 29, 2008; 381 (2): 361-72.

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity., Jazayeri A, Balestrini A, Garner E, Haber JE, Costanzo V., EMBO J. July 23, 2008; 27 (14): 1953-62.              

A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex., Dupré A, Boyer-Chatenet L, Sattler RM, Modi AP, Lee JH, Nicolette ML, Kopelovich L, Jasin M, Baer R, Paull TT, Gautier J., Nat Chem Biol. February 1, 2008; 4 (2): 119-25.

Telomere capping and cellular checkpoints: clues from fruit flies., Ciapponi L, Cenci G., Cytogenet Genome Res. January 1, 2008; 122 (3-4): 365-73.

Rapid activation of ATM on DNA flanking double-strand breaks., You Z, Bailis JM, Johnson SA, Dilworth SM, Hunter T., Nat Cell Biol. November 1, 2007; 9 (11): 1311-8.

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex., Dupré A, Boyer-Chatenet L, Gautier J., Nat Struct Mol Biol. May 1, 2006; 13 (5): 451-7.

ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks., Trenz K, Smith E, Smith S, Costanzo V., EMBO J. April 19, 2006; 25 (8): 1764-74.

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11., Di Virgilio M, Gautier J., J Cell Biol. December 5, 2005; 171 (5): 765-71.        

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1., You Z, Chahwan C, Bailis J, Hunter T, Russell P., Mol Cell Biol. July 1, 2005; 25 (13): 5363-79.

Novel nucleotide-binding sites in ATP-sensitive potassium channels formed at gating interfaces., Dong K, Tang LQ, MacGregor GG, Leng Q, Hebert SC., EMBO J. April 6, 2005; 24 (7): 1318-29.

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5., Kapoor TM, Mayer TU, Coughlin ML, Mitchison TJ., J Cell Biol. September 4, 2000; 150 (5): 975-88.                    

The cell nucleus in early bovine and caprine preimplantation embryos: fine structural cytochemistry and immunoelectron microscopy., Kopecny V, Biggiogera M, Pivko J, Grafenau P, Pavlok A, Malatesta M, Martin TE, Fakan S., Eur J Cell Biol. August 1, 1996; 70 (4): 361-72.

???pagination.result.page??? 1