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Summary Expression Phenotypes Gene Literature (83) GO Terms (0) Nucleotides (145) Proteins (70) Interactants (817) Wiki
XB-GENEPAGE-953989

Papers associated with mcc



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Bidirectional multiciliated cell extrusion is controlled by Notch-driven basal extrusion and Piezo1-driven apical extrusion., Ventrella R, Kim SK, Sheridan J, Grata A, Bresteau E, Hassan OA, Suva EE, Walentek P, Mitchell BJ., Development. September 1, 2023; 150 (17):                         

The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus., Angerilli A, Tait J, Berges J, Shcherbakova I, Pokrovsky D, Schauer T, Smialowski P, Hsam O, Mentele E, Nicetto D, Rupp RA., Life Sci Alliance. July 1, 2023; 6 (7):                         

CFAP45, a heterotaxy and congenital heart disease gene, affects cilia stability., Deniz E, Pasha M, Guerra ME, Viviano S, Ji W, Konstantino M, Jeffries L, Lakhani SA, Medne L, Skraban C, Krantz I, Khokha MK., Dev Biol. July 1, 2023; 499 75-88.                              

A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development., Lee J, Møller AF, Chae S, Bussek A, Park TJ, Kim Y, Lee HS, Pers TH, Kwon T, Sedzinski J, Natarajan KN., Sci Adv. April 7, 2023; 9 (14): eadd5745.                                                          

Multiciliated cells use filopodia to probe tissue mechanics during epithelial integration in vivo., Ventura G, Amiri A, Thiagarajan R, Tolonen M, Doostmohammadi A, Sedzinski J., Nat Commun. October 28, 2022; 13 (1): 6423.                                                

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex., Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang KL, Peart N, Singh MK, Lee H, Merriman B, Jodoin JN, Sitaram P, Lee LA, Fathalla R, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Roy S, Russell WK, Amiel J, Reversade B, Wagner EJ., Nat Commun. October 13, 2022; 13 (1): 6054.                    

Development of a multiciliated cell., Mahjoub MR, Nanjundappa R, Harvey MN., Curr Opin Cell Biol. August 1, 2022; 77 102105.  

Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function., Nommick A, Boutin C, Rosnet O, Schirmer C, Bazellières E, Thomé V, Loiseau E, Viallat A, Kodjabachian L., J Cell Sci. February 15, 2022; 135 (4):


CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis., Lee M, Nagashima K, Yoon J, Sun J, Wang Z, Carpenter C, Lee HK, Hwang YS, Westlake CJ, Daar IO., J Cell Biol. January 3, 2022; 221 (1):                       

Fluid Mechanics of Mosaic Ciliated Tissues., Boselli F, Jullien J, Lauga E, Goldstein RE., Phys Rev Lett. November 5, 2021; 127 (19): 198102.        

Tubulin acetylation promotes penetrative capacity of cells undergoing radial intercalation., Collins C, Kim SK, Ventrella R, Carruzzo HM, Wortman JC, Han H, Suva EE, Mitchell JW, Yu CC, Mitchell BJ., Cell Rep. August 17, 2021; 36 (7): 109556.                

DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes., Marquez J, Mann N, Arana K, Deniz E, Ji W, Konstantino M, Mis EK, Deshpande C, Jeffries L, McGlynn J, Hugo H, Widmeier E, Konrad M, Tasic V, Morotti R, Baptista J, Ellard S, Lakhani SA, Hildebrandt F, Khokha MK., J Med Genet. July 1, 2021; 58 (7): 453-464.                        

Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells., Kulkarni S, Marquez J, Date P, Ventrella R, Mitchell BJ, Khokha MK., Elife. June 29, 2021; 10                   

Protein turnover dynamics suggest a diffusion-to-capture mechanism for peri-basal body recruitment and retention of intraflagellar transport proteins., Hibbard JVK, Vazquez N, Satija R, Wallingford JB., Mol Biol Cell. June 1, 2021; 32 (12): 1171-1180.              

The Scf/Kit pathway implements self-organized epithelial patterning., Chuyen A, Rulquin C, Daian F, Thomé V, Clément R, Kodjabachian L, Pasini A., Dev Cell. March 22, 2021; 56 (6): 795-810.e7.

A role for Cep70 in centriole amplification in multiciliated cells., Kim SK, Brotslaw E, Thome V, Mitchell J, Ventrella R, Collins C, Mitchell B., Dev Biol. March 1, 2021; 471 10-17.          

Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling., Tasca A, Helmstädter M, Brislinger MM, Haas M, Mitchell B, Walentek P., Dev Cell. February 22, 2021; 56 (4): 525-539.e6.  

Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P., Genesis. February 1, 2021; 59 (1-2): e23406.          

Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes., Rao VG, Kulkarni SS., Genesis. February 1, 2021; 59 (1-2): e23414.  

Nucleoporin NUP205 plays a critical role in cilia and congenital disease., Marquez J, Bhattacharya D, Lusk CP, Khokha MK., Dev Biol. January 1, 2021; 469 46-53.                        

Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells., Collins C, Ventrella R, Mitchell BJ., Curr Top Dev Biol. January 1, 2021; 145 3-39.

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins., Lee C, Lee C, Cox RM, Papoulas O, Horani A, Drew K, Devitt CC, Brody SL, Marcotte EM, Wallingford JB., Elife. December 2, 2020; 9                             

CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia., Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J., Proc Natl Acad Sci U S A. June 16, 2020; 117 (24): 13571-13579.                

Nocodazole-Induced Expression and Phosphorylation of Anillin and Other Mitotic Proteins Are Decreased in DNA-Dependent Protein Kinase Catalytic Subunit-Deficient Cells and Rescued by Inhibition of the Anaphase-Promoting Complex/Cyclosome with proTAME but Not Apcin., Douglas P, Ye R, Radhamani S, Cobban A, Jenkins NP, Bartlett E, Roveredo J, Kettenbach AN, Lees-Miller SP., Mol Cell Biol. June 15, 2020; 40 (13):                   

Centriole Number and the Accumulation of Microtubules Modulate the Timing of Apical Insertion during Radial Intercalation., Collins C, Majekodunmi A, Mitchell B., Curr Biol. May 18, 2020; 30 (10): 1958-1964.e3.          

Serotonin and MucXS release by small secretory cells depend on Xpod, a SSC specific marker gene., Kurrle Y, Kunesch K, Bogusch S, Schweickert A., Genesis. February 1, 2020; 58 (2): e23344.              

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia., Haas M, Gómez Vázquez JL, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Vleminckx K, Walentek P., Cell Rep. September 24, 2019; 28 (13): 3338-3352.e6.                              

Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled., Lee M, Hwang YS, Yoon J, Sun J, Harned A, Nagashima K, Daar IO., J Cell Biol. August 5, 2019; 218 (8): 2659-2676.              

Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo., Bharathan NK, Dickinson AJG., Dev Biol. June 15, 2019; 450 (2): 115-131.                            

Biology of multiciliated cells., Boutin C, Kodjabachian L., Curr Opin Genet Dev. June 1, 2019; 56 1-7.      

Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance., Bustamante-Marin XM, Yin WN, Sears PR, Werner ME, Brotslaw EJ, Mitchell BJ, Jania CM, Zeman KL, Rogers TD, Herring LE, Refabért L, Thomas L, Amselem S, Escudier E, Legendre M, Grubb BR, Knowles MR, Zariwala MA, Ostrowski LE., Am J Hum Genet. February 7, 2019; 104 (2): 229-245.                                  

The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1., Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM., Front Physiol. January 1, 2019; 10 134.                

APC/C: current understanding and future perspectives., Yamano H., F1000Res. January 1, 2019; 8         

A liquid-like organelle at the root of motile ciliopathy., Huizar RL, Lee C, Boulgakov AA, Horani A, Tu F, Marcotte EM, Brody SL, Wallingford JB., Elife. December 18, 2018; 7                               

CDC20B is required for deuterosome-mediated centriole production in multiciliated cells., Revinski DR, Zaragosi LE, Boutin C, Ruiz-Garcia S, Deprez M, Thomé V, Rosnet O, Gay AS, Mercey O, Paquet A, Pons N, Ponzio G, Marcet B, Kodjabachian L, Barbry P., Nat Commun. November 7, 2018; 9 (1): 4668.              

The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice., Beckers A, Ott T, Schuster-Gossler K, Boldt K, Alten L, Ueffing M, Blum M, Gossler A., Sci Rep. October 2, 2018; 8 (1): 14678.            

WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation., Kulkarni SS, Griffin JN, Date PP, Liem KF, Khokha MK., Dev Cell. September 10, 2018; 46 (5): 595-610.e3.                              

TRRAP is a central regulator of human multiciliated cell formation., Wang Z, Plasschaert LW, Aryal S, Renaud NA, Yang Z, Choo-Wing R, Pessotti AD, Kirkpatrick ND, Cochran NR, Carbone W, Maher R, Lindeman A, Russ C, Reece-Hoyes J, McAllister G, Hoffman GR, Roma G, Jaffe AB., J Cell Biol. June 4, 2018; 217 (6): 1941-1955.                        

CLAMP/Spef1 regulates planar cell polarity signaling and asymmetric microtubule accumulation in the Xenopus ciliated epithelia., Kim SK, Zhang S, Werner ME, Brotslaw EJ, Mitchell JW, Altabbaa MM, Mitchell BJ., J Cell Biol. May 7, 2018; 217 (5): 1633-1641.                    

Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function., Tu F, Sedzinski J, Ma Y, Marcotte EM, Wallingford JB., J Cell Sci. January 29, 2018; 131 (3):             

Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression., Quigley IK, Kintner C., PLoS Genet. January 19, 2017; 13 (1): e1006538.            

RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells., Sedzinski J, Hannezo E, Tu F, Biro M, Wallingford JB., J Cell Sci. January 15, 2017; 130 (2): 420-428.                

A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling., Ji Z, Gao H, Jia L, Li B, Yu H., Elife. January 10, 2017; 6               

What we can learn from a tadpole about ciliopathies and airway diseases: Using systems biology in Xenopus to study cilia and mucociliary epithelia., Walentek P, Quigley IK., Genesis. January 1, 2017; 55 (1-2):       

La-related protein 6 controls ciliated cell differentiation., Manojlovic Z, Earwood R, Kato A, Perez D, Cabrera OA, Didier R, Megraw TL, Stefanovic B, Kato Y., Cilia. January 1, 2017; 6 4.                

Foxn4 promotes gene expression required for the formation of multiple motile cilia., Campbell EP, Quigley IK, Kintner C., Development. December 15, 2016; 143 (24): 4654-4664.                                  

Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis., Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM., Elife. September 13, 2016; 5                                   

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery., Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun DA, Pierquin G, Biver A, Wagner K, Malfroot A, Panigrahi I, Franco B, Al-Lami HA, Yeung Y, Choi YJ, University of Washington Center for Mendelian Genomics, Duffourd Y, Faivre L, Rivière JB, Chen J, Liu KJ, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB., Nat Genet. June 1, 2016; 48 (6): 648-56.                              

MicroRNAs as key regulators of GTPase-mediated apical actin reorganization in multiciliated epithelia., Mercey O, Kodjabachian L, Barbry P, Marcet B., Small GTPases. April 2, 2016; 7 (2): 54-8.  

c21orf59/kurly Controls Both Cilia Motility and Polarization., Jaffe KM, Grimes DT, Schottenfeld-Roames J, Werner ME, Ku TS, Kim SK, Pelliccia JL, Morante NF, Mitchell BJ, Burdine RD., Cell Rep. March 1, 2016; 14 (8): 1841-9.                  

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