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Summary Expression Phenotypes Gene Literature (56) GO Terms (0) Nucleotides (47) Proteins (31) Interactants (487) Wiki
XB-GENEPAGE-957719

Papers associated with itk



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Ectopic induction of dorsal mesoderm by overexpression of Xwnt-8 elevates the neural competence of Xenopus ectoderm., Otte AP, Moon RT., Dev Biol. July 1, 1992; 152 (1): 184-7.    

Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development., Shook D, Keller R., Mech Dev. November 1, 2003; 120 (11): 1351-83.

Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski., Takeda M, Mizuide M, Oka M, Watabe T, Inoue H, Suzuki H, Fujita T, Imamura T, Miyazono K, Miyazawa K., Mol Biol Cell. March 1, 2004; 15 (3): 963-72.                

A slug, a fox, a pair of sox: transcriptional responses to neural crest inducing signals., Heeg-Truesdell E, LaBonne C., Birth Defects Res C Embryo Today. June 1, 2004; 72 (2): 124-39.      

Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs., Katoh M, Katoh M., Oncol Rep. October 1, 2005; 14 (4): 1083-6.

The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells., Atherly LO, Lucas JA, Felices M, Yin CC, Reiner SL, Berg LJ., Immunity. July 1, 2006; 25 (1): 79-91.

Wnt11-R signaling regulates a calcium sensitive EMT event essential for dorsal fin development of Xenopus., Garriock RJ, Krieg PA., Dev Biol. April 1, 2007; 304 (1): 127-40.            

Modulating the activity of neural crest regulatory factors., Taylor KM, LaBonne C., Curr Opin Genet Dev. August 1, 2007; 17 (4): 326-31.  

Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus., Langer EM, Feng Y, Zhaoyuan H, Rauscher FJ, Kroll KL, Longmore GD., Dev Cell. March 1, 2008; 14 (3): 424-36.        

Epilysin (MMP-28)--structure, expression and potential functions., Illman SA, Lohi J, Keski-Oja J., Exp Dermatol. November 1, 2008; 17 (11): 897-907.

Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe., Klymkowsky MW, Savagner P., Am J Pathol. May 1, 2009; 174 (5): 1588-93.

Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development., Rhee DY, Zhao XQ, Francis RJ, Huang GY, Mably JD, Lo CW., Development. September 1, 2009; 136 (18): 3185-93.          

Characterization of molecular markers to assess cardiac cushions formation in Xenopus., Lee YH, Lee YH, Saint-Jeannet JP., Dev Dyn. December 1, 2009; 238 (12): 3257-65.            

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition., Walsh LA, Damjanovski S., Cell Commun Signal. May 2, 2011; 9 (1): 10.            

Evidence for partial epithelial-to-mesenchymal transition (pEMT) and recruitment of motile blastoderm edge cells during avian epiboly., Futterman MA, García AJ, Zamir EA., Dev Dyn. June 1, 2011; 240 (6): 1502-11.

The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1., Lander R, Nordin K, LaBonne C., J Cell Biol. July 11, 2011; 194 (1): 17-25.            

Targeted inactivation of Snail family EMT regulatory factors by a Co(III)-Ebox conjugate., Harney AS, Meade TJ, LaBonne C., PLoS One. January 1, 2012; 7 (2): e32318.            

Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migration., Theveneau E, Mayor R., Dev Biol. June 1, 2012; 366 (1): 34-54.

The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition., Barriga EH, Maxwell PH, Reyes AE, Mayor R., J Cell Biol. May 27, 2013; 201 (5): 759-76.                  

Role of the hypoxia response pathway in lens formation during embryonic development of Xenopus laevis., Baba K, Muraguchi T, Imaoka S., FEBS Open Bio. October 23, 2013; 3 490-5.        

A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance., Livigni A, Peradziryi H, Sharov AA, Chia G, Hammachi F, Migueles RP, Sukparangsi W, Pernagallo S, Bradley M, Nichols J, Ko MSH, Brickman JM., Curr Biol. November 18, 2013; 23 (22): 2233-2244.                                    

In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity., Kuriyama S, Theveneau E, Benedetto A, Parsons M, Tanaka M, Charras G, Kabla A, Mayor R., J Cell Biol. July 7, 2014; 206 (1): 113-27.                                

A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis., Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G., Cell. November 6, 2014; 159 (4): 844-56.              

Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development., Tien CL, Jones A, Wang H, Gerigk M, Nozell S, Chang C., Development. February 15, 2015; 142 (4): 722-31.                

A Novel Role for VICKZ Proteins in Maintaining Epithelial Integrity during Embryogenesis., Carmel MS, Kahane N, Oberman F, Miloslavski R, Sela-Donenfeld D, Kalcheim C, Yisraeli JK., PLoS One. August 4, 2015; 10 (8): e0136408.              

Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces., Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R., Dev Cell. August 24, 2015; 34 (4): 421-34.                                            

Xenopus Limb bud morphogenesis., Keenan SR, Beck CW., Dev Dyn. March 1, 2016; 245 (3): 233-43.            

Hmga2 is required for neural crest cell specification in Xenopus laevis., Macrì S, Simula L, Pellarin I, Pegoraro S, Onorati M, Sgarra R, Manfioletti G, Vignali R., Dev Biol. March 1, 2016; 411 (1): 25-37.                                        

Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure., Ray HJ, Niswander LA., Development. April 1, 2016; 143 (7): 1192-204.

Identification of anti-cancer chemical compounds using Xenopus embryos., Tanaka M, Kuriyama S, Itoh G, Kohyama A, Iwabuchi Y, Shibata H, Yashiro M, Aiba N., Cancer Sci. June 1, 2016; 107 (6): 803-11.            

Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin., Gouignard N, Maccarana M, Strate I, von Stedingk K, Malmström A, Pera EM., Dis Model Mech. June 1, 2016; 9 (6): 607-20.                                      

Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2., Rabadán MA, Herrera A, Fanlo L, Usieto S, Carmona-Fontaine C, Barriga EH, Mayor R, Pons S, Martí E., Development. June 15, 2016; 143 (12): 2194-205.          

Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ, Xie SX, Chen YT, Xue JL, Zhang CJ, Zhu F., World J Gastroenterol. September 7, 2016; 22 (33): 7486-99.      

FGF and canonical Wnt signaling cooperate to induce paraxial mesoderm from tailbud neuromesodermal progenitors through regulation of a two-step epithelial to mesenchymal transition., Goto H, Kimmey SC, Row RH, Matus DQ, Martin BL., Development. April 15, 2017; 144 (8): 1412-1424.

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

PFKFB4 control of AKT signaling is essential for premigratory and migratory neural crest formation., Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH., Development. November 15, 2017; 144 (22): 4183-4194.                                

MiR-29a-5p inhibits proliferation and invasion and induces apoptosis in endometrial carcinoma via targeting TPX2., Jiang T, Sui D, You D, Yao S, Zhang L, Wang Y, Zhao J, Zhang Y., Cell Cycle. January 1, 2018; 17 (10): 1268-1278.

MMP14 Regulates Cranial Neural Crest Epithelial-to-Mesenchymal Transition and Migration., Garmon T, Wittling M, Nie S., Dev Dyn. September 1, 2018; 247 (9): 1083-1092.            

TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z, Zheng B, Li J, Lv X, Zhang H, Yu F, Kong L, Li Y, Yu M, Fang L, Liang B., Biomed Pharmacother. November 1, 2018; 107 1286-1293.

The Ric-8A/Gα13/FAK signalling cascade controls focal adhesion formation during neural crest cell migration in Xenopus., Toro-Tapia G, Villaseca S, Beyer A, Roycroft A, Marcellini S, Mayor R, Torrejón M., Development. November 21, 2018; 145 (22):                               

The neural border: Induction, specification and maturation of the territory that generates neural crest cells., Pla P, Monsoro-Burq AH., Dev Biol. December 1, 2018; 444 Suppl 1 S36-S46.    

DNp73-induced degradation of tyrosinase links depigmentation with EMT-driven melanoma progression., Fürst K, Steder M, Logotheti S, Angerilli A, Spitschak A, Marquardt S, Schumacher T, Engelmann D, Herchenröder O, Rupp RAW, Pützer BM., Cancer Lett. February 1, 2019; 442 299-309.

Epithelial-Mesenchymal Transition Promotes the Differentiation Potential of Xenopus tropicalis Immature Sertoli Cells., Nguyen TMX, Vegrichtova M, Tlapakova T, Krulova M, Krylov V., Stem Cells Int. May 5, 2019; 2019 8387478.                                            

In vivo Neural Crest Cell Migration Is Controlled by "Mixotaxis"., Barriga EH, Theveneau E., Front Physiol. January 1, 2020; 11 586432.    

Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome., Alharatani R, Ververi A, Beleza-Meireles A, Ji W, Mis E, Patterson QT, Griffin JN, Bhujel N, Chang CA, Dixit A, Konstantino M, Healy C, Hannan S, Neo N, Cash A, Li D, Bhoj E, Zackai EH, Cleaver R, Baralle D, McEntagart M, Newbury-Ecob R, Scott R, Hurst JA, Au PYB, Hosey MT, Khokha M, Marciano DK, Lakhani SA, Liu KJ, Liu KJ., Hum Mol Genet. July 21, 2020; 29 (11): 1900-1921.                  

Using Xenopus Neural Crest Explants to Study Epithelial-Mesenchymal Transition., Gouignard N, Rouvière C, Theveneau E., Methods Mol Biol. January 1, 2021; 2179 257-274.

Evolution of Somite Compartmentalization: A View From Xenopus., Della Gaspera B, Weill L, Chanoine C., Front Cell Dev Biol. January 1, 2021; 9 790847.                  

Auto-inhibitory intramolecular S5/S6 interaction in the TRPV6 channel regulates breast cancer cell migration and invasion., Cai R, Wang L, Liu X, Michalak M, Tang J, Peng JB, Chen XZ., Commun Biol. August 19, 2021; 4 (1): 990.              

An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus., Godden AM, Antonaci M, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN., Dev Biol. March 1, 2022; 483 66-75.        

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma., Taylor W, Deschamps S, Reboutier D, Paillard L, Méreau A, Audic Y., Cancer Res Commun. December 1, 2022; 2 (12): 1669-1683.                                

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