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Summary Expression Phenotypes Gene Literature (145) GO Terms (17) Nucleotides (1322) Proteins (74) Interactants (871) Wiki
XB-GENEPAGE-967584

Papers associated with cdc42



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A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos., Drechsel DN, Hyman AA, Hall A, Glotzer M., Curr Biol. January 1, 1997; 7 (1): 12-23.

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck., Lu W, Katz S, Gupta R, Mayer BJ., Curr Biol. February 1, 1997; 7 (2): 85-94.

A member of the Ste20/PAK family of protein kinases is involved in both arrest of Xenopus oocytes at G2/prophase of the first meiotic cell cycle and in prevention of apoptosis., Faure S, Vigneron S, Dorée M, Morin N., EMBO J. September 15, 1997; 16 (18): 5550-61.

Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts., Ma L, Cantley LC, Janmey PA, Kirschner MW., J Cell Biol. March 9, 1998; 140 (5): 1125-36.              

Cdc42 is required for membrane dependent actin polymerization in vitro., Moreau V, Way M., FEBS Lett. May 15, 1998; 427 (3): 353-6.

Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri., Suzuki T, Miki H, Takenawa T, Sasakawa C., EMBO J. May 15, 1998; 17 (10): 2767-76.

Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain., Leblanc V, Tocque B, Delumeau I., Mol Cell Biol. September 1, 1998; 18 (9): 5567-78.

The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42., Ma L, Rohatgi R, Kirschner MW., Proc Natl Acad Sci U S A. December 22, 1998; 95 (26): 15362-7.

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly., Rohatgi R, Ma L, Miki H, Lopez M, Kirchhausen T, Takenawa T, Kirschner MW., Cell. April 16, 1999; 97 (2): 221-31.

Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility., Mounier J, Laurent V, Hall A, Fort P, Carlier MF, Sansonetti PJ, Egile C., J Cell Sci. July 1, 1999; 112 ( Pt 13) 2069-80.

The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo., Ruchhoeft ML, Ohnuma S, McNeill L, Holt CE, Harris WA., J Neurosci. October 1, 1999; 19 (19): 8454-63.

alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase., Yoshii S, Tanaka M, Otsuki Y, Wang DY, Guo RJ, Zhu Y, Takeda R, Hanai H, Kaneko E, Sugimura H., Oncogene. October 7, 1999; 18 (41): 5680-90.

Regulation of Xenopus p21-activated kinase (X-PAK2) by Cdc42 and maturation-promoting factor controls Xenopus oocyte maturation., Cau J, Faure S, Vigneron S, Labbé JC, Delsert C, Morin N., J Biol Chem. January 28, 2000; 275 (4): 2367-75.

Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo., Li Z, Van Aelst L, Cline HT., Nat Neurosci. March 1, 2000; 3 (3): 217-25.

Rho family GTPase Cdc42 is essential for the actin-based motility of Shigella in mammalian cells., Suzuki T, Mimuro H, Miki H, Takenawa T, Sasaki T, Nakanishi H, Takai Y, Sasakawa C., J Exp Med. June 5, 2000; 191 (11): 1905-20.                      

Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis., Djiane A, Riou J, Umbhauer M, Boucaut J, Shi D., Development. July 1, 2000; 127 (14): 3091-100.    

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate., Rohatgi R, Ho HY, Kirschner MW., J Cell Biol. September 18, 2000; 150 (6): 1299-310.                    

Signal transduction. N-WASP regulation--the sting in the tail., Fawcett J, Pawson T., Science. October 27, 2000; 290 (5492): 725-6.

Rho GTPases as modulators of the estrogen receptor transcriptional response., Su LF, Knoblauch R, Garabedian MJ., J Biol Chem. February 2, 2001; 276 (5): 3231-7.

Lysine and polyamines are substrates for transglutamination of Rho by the Bordetella dermonecrotic toxin., Schmidt G, Goehring UM, Schirmer J, Uttenweiler-Joseph S, Wilm M, Lohmann M, Giese A, Schmalzing G, Aktories K., Infect Immun. December 1, 2001; 69 (12): 7663-70.

A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization., Cau J, Faure S, Comps M, Delsert C, Morin N., J Cell Biol. December 10, 2001; 155 (6): 1029-42.                    

The effect of IQGAP1 on Xenopus embryonic ectoderm requires Cdc42., Sokol SY, Li Z, Sacks DB., J Biol Chem. December 21, 2001; 276 (51): 48425-30.

Regulation of rho GTPases by crosstalk and neuronal activity in vivo., Li Z, Aizenman CD, Cline HT., Neuron. February 28, 2002; 33 (5): 741-50.

Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation., Wei L, Imanaka-Yoshida K, Wang L, Zhan S, Schneider MD, DeMayo FJ, Schwartz RJ., Development. April 1, 2002; 129 (7): 1705-14.

Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca2+ signaling pathway., Choi SC, Han JK., Dev Biol. April 15, 2002; 244 (2): 342-57.                  

Non-canonical Wnt signalling and regulation of gastrulation movements., Tada M, Concha ML, Heisenberg CP., Semin Cell Dev Biol. June 1, 2002; 13 (3): 251-60.

Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes., Kanzaki M, Watson RT, Hou JC, Stamnes M, Saltiel AR, Pessin JE., Mol Biol Cell. July 1, 2002; 13 (7): 2334-46.

Pak1 phosphorylation on t212 affects microtubules in cells undergoing mitosis., Banerjee M, Worth D, Prowse DM, Nikolic M., Curr Biol. July 23, 2002; 12 (14): 1233-9.

Plakoglobin is required for maintenance of the cortical actin skeleton in early Xenopus embryos and for cdc42-mediated wound healing., Kofron M, Heasman J, Lang SA, Wylie CC., J Cell Biol. August 19, 2002; 158 (4): 695-708.                  

Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases., Sin WC, Haas K, Ruthazer ES, Cline HT., Nature. October 3, 2002; 419 (6906): 475-80.

The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling., Hikasa H, Shibata M, Hiratani I, Taira M., Development. November 1, 2002; 129 (22): 5227-39.                        

Signalling and crosstalk of Rho GTPases in mediating axon guidance., Yuan XB, Jin M, Xu X, Song YQ, Wu CP, Poo MM, Duan S., Nat Cell Biol. January 1, 2003; 5 (1): 38-45.

XGef is a CPEB-interacting protein involved in Xenopus oocyte maturation., Reverte CG, Yuan L, Keady BT, Lacza C, Attfield KR, Mahon GM, Freeman B, Whitehead IP, Hake LE., Dev Biol. March 15, 2003; 255 (2): 383-98.

Localization of two IQGAPs in cultured cells and early embryos of Xenopus laevis., Yamashiro S, Noguchi T, Mabuchi I., Cell Motil Cytoskeleton. May 1, 2003; 55 (1): 36-50.

Activation of Gbetagamma signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation., Penzo-Mendèz A, Umbhauer M, Djiane A, Boucaut JC, Riou JF., Dev Biol. May 15, 2003; 257 (2): 302-14.    

Cdc42-dependent actin polymerization during compensatory endocytosis in Xenopus eggs., Sokac AM, Co C, Taunton J, Bement W., Nat Cell Biol. August 1, 2003; 5 (8): 727-32.

Potential roles of the nucleotide exchange factor ECT2 and Cdc42 GTPase in spindle assembly in Xenopus egg cell-free extracts., Tatsumoto T, Sakata H, Dasso M, Miki T., J Cell Biochem. December 1, 2003; 90 (5): 892-900.

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation., Wang HR, Zhang Y, Ozdamar B, Ogunjimi AA, Alexandrova E, Thomsen GH, Wrana JL., Science. December 5, 2003; 302 (5651): 1775-9.

Zebrafish Mir antagonizes Frizzled 7-induced gastrulation defects., Knowlton MN, Kelly GM., Zebrafish. January 1, 2004; 1 (2): 133-44.

Rho guanine nucleotide exchange factor xNET1 implicated in gastrulation movements during Xenopus development., Miyakoshi A, Ueno N, Kinoshita N., Differentiation. February 1, 2004; 72 (1): 48-55.                  

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex., Ho HY, Rohatgi R, Lebensohn AM, Le Ma, Li J, Gygi SP, Kirschner MW., Cell. July 23, 2004; 118 (2): 203-16.

Cdc42 Effector Protein 2 (XCEP2) is required for normal gastrulation and contributes to cellular adhesion in Xenopus laevis., Nelson KK, Nelson RW., BMC Dev Biol. October 8, 2004; 4 13.                  

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance., Meriane M, Tcherkezian J, Webber CA, Danek EI, Triki I, McFarlane S, Bloch-Gallego E, Lamarche-Vane N., J Cell Biol. November 22, 2004; 167 (4): 687-98.                  

Concentric zones of active RhoA and Cdc42 around single cell wounds., Benink HA, Bement WM., J Cell Biol. January 31, 2005; 168 (3): 429-39.                  

Ca2+-dependent regulation of rho GTPases triggers turning of nerve growth cones., Jin M, Guan CB, Jiang YA, Chen G, Zhao CT, Cui K, Song YQ, Wu CP, Poo MM, Yuan XB., J Neurosci. March 2, 2005; 25 (9): 2338-47.

JNK and ROKalpha function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movements., Kim GH, Han JK., Dev Dyn. April 1, 2005; 232 (4): 958-68.  

FGF signal regulates gastrulation cell movements and morphology through its target NRH., Chung HA, Hyodo-Miura J, Nagamune T, Ueno N., Dev Biol. June 1, 2005; 282 (1): 95-110.                          

Src-dependent tyrosine phosphorylation at the tips of growth cone filopodia promotes extension., Robles E, Woo S, Gomez TM., J Neurosci. August 17, 2005; 25 (33): 7669-81.

Role of crescent in convergent extension movements by modulating Wnt signaling in early Xenopus embryogenesis., Shibata M, Itoh M, Hikasa H, Taira S, Taira M., Mech Dev. December 1, 2005; 122 (12): 1322-39.                    

In vitro reconstitution of cdc42-mediated actin assembly using purified components., Ho HY, Rohatgi R, Lebensohn AM, Kirschner MW., Methods Enzymol. January 1, 2006; 406 174-90.

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