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Summary Expression Phenotypes Gene Literature (60) GO Terms (21) Nucleotides (124) Proteins (64) Interactants (382) Wiki
XB-GENEPAGE-967715

Papers associated with pak1



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Xenopsin- and neurotensin-like peptides in gastric juice from patients with duodenal ulcers., Shaw C, Stöckmann F, Conlon JM., Eur J Clin Invest. August 1, 1987; 17 (4): 306-12.


Arginine vasotocin (AVT) and AVT-related peptide are major aldosterone-releasing factors in the bullfrog neurointermediate lobe., Iwamuro S, Hayashi H, Yamashita M, Kikuyama S., Gen Comp Endocrinol. December 1, 1991; 84 (3): 412-8.


Identification of xenin, a xenopsin-related peptide, in the human gastric mucosa and its effect on exocrine pancreatic secretion., Feurle GE, Hamscher G, Kusiek R, Meyer HE, Metzger JW., J Biol Chem. November 5, 1992; 267 (31): 22305-9.


Purification of antimicrobial peptides from an extract of the skin of Xenopus laevis using heparin-affinity HPLC: characterization by ion-spray mass spectrometry., James S, Gibbs BF, Toney K, Bennett HP., Anal Biochem. February 15, 1994; 217 (1): 84-90.


Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes., Polverino A, Frost J, Yang P, Hutchison M, Neiman AM, Cobb MH, Marcus S., J Biol Chem. November 3, 1995; 270 (44): 26067-70.


Phosphorylation events associated with different states of activation of a hepatic cardiolipin/protease-activated protein kinase. Structural identity to the protein kinase N-type protein kinases., Peng B, Morrice NA, Groenen LC, Wettenhall RE., J Biol Chem. December 13, 1996; 271 (50): 32233-40.


Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck., Lu W, Katz S, Gupta R, Mayer BJ., Curr Biol. February 1, 1997; 7 (2): 85-94.


A member of the Ste20/PAK family of protein kinases is involved in both arrest of Xenopus oocytes at G2/prophase of the first meiotic cell cycle and in prevention of apoptosis., Faure S, Vigneron S, Dorée M, Morin N., EMBO J. September 15, 1997; 16 (18): 5550-61.


Control of G2/M transition in Xenopus by a member of the p21-activated kinase (PAK) family: a link between protein kinase A and PAK signaling pathways?, Faure S, Vigneron S, Galas S, Brassac T, Delsert C, Morin N., J Biol Chem. February 5, 1999; 274 (6): 3573-9.


alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase., Yoshii S, Tanaka M, Otsuki Y, Wang DY, Guo RJ, Zhu Y, Takeda R, Hanai H, Kaneko E, Sugimura H., Oncogene. October 7, 1999; 18 (41): 5680-90.


Regulation of Xenopus p21-activated kinase (X-PAK2) by Cdc42 and maturation-promoting factor controls Xenopus oocyte maturation., Cau J, Faure S, Vigneron S, Labbé JC, Delsert C, Morin N., J Biol Chem. January 28, 2000; 275 (4): 2367-75.


The cytoskeletal effector xPAK1 is expressed during both ear and lateral line development in Xenopus., Islam N, Poitras L, Moss T., Int J Dev Biol. February 1, 2000; 44 (2): 245-8.          


ICln is essential for cellular and early embryonic viability., Pu WT, Wickman K, Clapham DE., J Biol Chem. April 28, 2000; 275 (17): 12363-6.


A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization., Cau J, Faure S, Comps M, Delsert C, Morin N., J Cell Biol. December 10, 2001; 155 (6): 1029-42.                    


Pak1 phosphorylation on t212 affects microtubules in cells undergoing mitosis., Banerjee M, Worth D, Prowse DM, Nikolic M., Curr Biol. July 23, 2002; 12 (14): 1233-9.


Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1., Luo ZG, Wang Q, Zhou JZ, Wang J, Luo Z, Liu M, He X, Wynshaw-Boris A, Xiong WC, Lu B, Mei L., Neuron. August 1, 2002; 35 (3): 489-505.


XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis., Souopgui J, Sölter M, Pieler T., EMBO J. December 2, 2002; 21 (23): 6429-39.


Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition., Tran NH, Frost JA., J Biol Chem. March 28, 2003; 278 (13): 11221-6.


PAK interacts with NCK and MLK2 to regulate the activation of jun N-terminal kinase., Poitras L, Jean S, Islam N, Moss T., FEBS Lett. May 22, 2003; 543 (1-3): 129-35.


The catalytic domain of xPAK1 is sufficient to induce myosin II dependent in vivo cell fragmentation independently of other apoptotic events., Bisson N, Islam N, Poitras L, Jean S, Bresnick A, Moss T., Dev Biol. November 15, 2003; 263 (2): 264-81.  


Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance., Meriane M, Tcherkezian J, Webber CA, Danek EI, Triki I, McFarlane S, Bloch-Gallego E, Lamarche-Vane N., J Cell Biol. November 22, 2004; 167 (4): 687-98.                  


The Xenopus laevis morphogenetic factor, tumorhead, causes defects in polarized growth and cytokinesis in the fission yeast, Schizosaccharomyces pombe., Wu CF, Yang P, Traverso EE, Etkin LD, Marcus S., Biochem Biophys Res Commun. December 10, 2004; 325 (2): 439-44.


Xenopus p21-activated kinase 5 regulates blastomeres' adhesive properties during convergent extension movements., Faure S, Cau J, de Santa Barbara P, Bigou S, Ge Q, Delsert C, Morin N., Dev Biol. January 15, 2005; 277 (2): 472-92.    


EphA4 signaling regulates blastomere adhesion in the Xenopus embryo by recruiting Pak1 to suppress Cdc42 function., Bisson N, Poitras L, Mikryukov A, Tremblay M, Moss T., Mol Biol Cell. March 1, 2007; 18 (3): 1030-43.                  


Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development., Luo T, Xu Y, Xu Y, Hoffman TL, Zhang T, Schilling T, Sargent TD., Development. April 1, 2007; 134 (7): 1279-89.      


Tumorhead distribution to cytoplasmic membrane of neural plate cells is positively regulated by Xenopus p21-activated kinase 1 (X-PAK1)., Wu CF, Delsert C, Faure S, Traverso EE, Kloc M, Kuang J, Etkin LD, Morin N., Dev Biol. August 1, 2007; 308 (1): 169-86.              


The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties., Kreis P, Rousseau V, Thévenot E, Combeau G, Barnier JV., J Neurochem. August 1, 2008; 106 (3): 1184-97.


Rac regulates the interaction of fascin with protein kinase C in cell migration., Parsons M, Adams JC., J Cell Sci. September 1, 2008; 121 (Pt 17): 2805-13.


Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization., Dzamba BJ, Jakab KR, Marsden M, Schwartz MA, DeSimone DW., Dev Cell. March 1, 2009; 16 (3): 421-32.


Role of p21-activated kinase in cell polarity and directional mesendoderm migration in the Xenopus gastrula., Nagel M, Luu O, Bisson N, Macanovic B, Moss T, Winklbauer R., Dev Dyn. July 1, 2009; 238 (7): 1709-26.  


Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis., Bompard G, Rabeharivelo G, Frank M, Cau J, Delsert C, Morin N., J Cell Biol. September 6, 2010; 190 (5): 807-22.                    


Phosphoinositides are essential coactivators for p21-activated kinase 1., Strochlic TI, Viaud J, Rennefahrt UE, Anastassiadis T, Peterson JR., Mol Cell. November 12, 2010; 40 (3): 493-500.


Isolation and characterisation of prolactin-releasing peptide in chicks and its effect on prolactin release and feeding behaviour., Tachibana T, Moriyama S, Takahashi A, Tsukada A, Oda A, Takeuchi S, Sakamoto T., J Neuroendocrinol. January 1, 2011; 23 (1): 74-81.


Activity of the RhoU/Wrch1 GTPase is critical for cranial neural crest cell migration., Fort P, Guémar L, Vignal E, Morin N, Notarnicola C, de Santa Barbara P, Faure S., Dev Biol. February 15, 2011; 350 (2): 451-63.                      


Posttranscriptional activation of gene expression in Xenopus laevis oocytes by microRNA-protein complexes (microRNPs)., Mortensen RD, Serra M, Steitz JA, Vasudevan S., Proc Natl Acad Sci U S A. May 17, 2011; 108 (20): 8281-6.          


WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters., Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP., J Biol Chem. August 26, 2011; 286 (34): 30171-80.              


Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus., Nie S, Kee Y, Bronner-Fraser M., Mol Biol Cell. September 1, 2011; 22 (18): 3355-65.                                                


Pak6 protein kinase is a novel effector of an atypical Rho family GTPase Chp/RhoV., Shepelev MV, Korobko IV., Biochemistry (Mosc). January 1, 2012; 77 (1): 26-32.


Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus., Park BY, Hong CS, Weaver JR, Rosocha EM, Saint-Jeannet JP., Dev Biol. February 1, 2012; 362 (1): 65-75.                


The p21-activated kinase Pak1 regulates induction and migration of the neural crest in Xenopus., Bisson N, Wedlich D, Moss T., Cell Cycle. April 1, 2012; 11 (7): 1316-24.


The endocytic adapter E-Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling., Jean S, Tremblay MG, Herdman C, Guillou F, Moss T., Biol Open. August 15, 2012; 1 (8): 731-8.          


Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin., Valls G, Codina M, Miller RK, Del Valle-Pérez B, Vinyoles M, Caelles C, McCrea PD, García de Herreros A, Duñach M., J Cell Sci. November 15, 2012; 125 (Pt 22): 5288-301.                


PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth., Santiago-Medina M, Gregus KA, Gomez TM., J Cell Sci. March 1, 2013; 126 (Pt 5): 1122-33.


Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly., Soto X, Li J, Lea R, Dubaissi E, Papalopulu N, Amaya E., Proc Natl Acad Sci U S A. July 2, 2013; 110 (27): 11029-34.                                      


Exploiting polypharmacology for drug target deconvolution., Gujral TS, Peshkin L, Kirschner MW., Proc Natl Acad Sci U S A. April 1, 2014; 111 (13): 5048-53.        


EphA4-dependent Brachyury expression is required for dorsal mesoderm involution in the Xenopus gastrula., Evren S, Wen JW, Luu O, Damm EW, Nagel M, Winklbauer R., Development. October 1, 2014; 141 (19): 3649-61.                              


Atypical RhoV and RhoU GTPases control development of the neural crest., Faure S, Fort P., Small GTPases. October 2, 2015; 6 (4): 174-7.


Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES., Watson JR, Fox HM, Nietlispach D, Gallop JL, Owen D, Mott HR., J Biol Chem. June 24, 2016; 291 (26): 13875-90.                  


Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation., Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J, Jho EH., Cell Death Differ. October 1, 2016; 23 (10): 1638-47.


Intracytoplasmic Transport of Hepatitis B Virus Capsids., Osseman Q, Kann M., Methods Mol Biol. January 1, 2017; 1540 37-51.

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