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Summary Expression Phenotypes Gene Literature (436) GO Terms (0) Nucleotides (18) Proteins (9) Interactants (232) Wiki

Papers associated with kcnh2 (and Disease Ontology)

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Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer., Levin M., Cell. April 1, 2021;               

Loss-of-function variants in Kv 11.1 cardiac channels as a biomarker for SUDEP., Soh MS, Bagnall RD, Bennett MF, Bleakley LE, Mohamed Syazwan ES, Phillips AM, Chiam MDF, McKenzie CE, Hildebrand M, Crompton D, Bahlo M, Semsarian C, Scheffer IE, Berkovic SF, Reid CA., Ann Clin Transl Neurol. January 1, 2021; 8 (7): 1422-1432.                

Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms., Bohannon BM, de la Cruz A, Wu X, Jowais JJ, Perez ME, Dykxhoorn DM, Liin SI, Larsson HP., Elife. January 1, 2020; 9                                                               

Electrophysiological effects of non-vitamin K antagonist oral anticoagulants on atrial repolarizing potassium channels., Wiedmann F, Schlund D, Kraft M, Nietfeld J, Katus HA, Schmidt C, Thomas D., Europace. January 1, 2020; 22 (9): 1409-1418.

Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors., Florentino IF, Silva DPB, Cardoso CS, Menegatti R, de Carvalho FS, Lião LM, Pinto PM, Peigneur S, Costa EA, Tytgat J., Biomed Pharmacother. July 1, 2019; 115 108915.

The molecular determinants of R-roscovitine block of hERG channels., Cernuda B, Fernandes CT, Allam SM, Orzillo M, Suppa G, Chia Chang Z, Athanasopoulos D, Buraei Z., PLoS One. January 1, 2019; 14 (9): e0217733.                      

Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain., de la Peña P, Domínguez P, Barros F., Pflugers Arch. January 1, 2018; 470 (7): 1069-1085.                

High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance., Steffensen AB, Refaat MM, David JP, Mujezinovic A, Calloe K, Wojciak J, Nussbaum RL, Scheinman MM, Schmitt N., Sci Rep. September 21, 2015; 5 10009.              

The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT., Mechakra A, Vincent Y, Chevalier P, Millat G, Ficker E, Jastrzebski M, Poulin H, Pouliot V, Chahine M, Christé G., Gene. February 25, 2014; 536 (2): 348-56.            

ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel., Wei X, Sun H, Yan H, Zhang C, Zhang S, Liu X, Hua N, Ma X, Zheng J., Cancer Biol Ther. May 1, 2013; 14 (5): 450-7.

Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P, Kisselbach J, Schweizer PA, Becker R, Katus HA, Thomas D., Gene. December 10, 2012; 511 (1): 26-33.        

A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels., Gustina AS, Trudeau MC., Proc Natl Acad Sci U S A. August 4, 2009; 106 (31): 13082-7.          

Biophysical properties of zebrafish ether-à-go-go related gene potassium channels., Scholz EP, Niemer N, Hassel D, Zitron E, Bürgers HF, Bloehs R, Seyler C, Scherer D, Thomas D, Kathöfer S, Katus HA, Rottbauer WA, Karle CA., Biochem Biophys Res Commun. April 3, 2009; 381 (2): 159-64.

The influence of extracellular acidosis on the effect of IKr blockers., Lin C, Ke X, Cvetanovic I, Ranade V, Somberg J., J Cardiovasc Pharmacol Ther. March 1, 2005; 10 (1): 67-76.

Novel characteristics of a misprocessed mutant HERG channel linked to hereditary long QT syndrome., Ficker E, Thomas D, Viswanathan PC, Dennis AT, Priori SG, Napolitano C, Memmi M, Wible BA, Kaufman ES, Iyengar S, Schwartz PJ, Rudy Y, Brown AM., Am J Physiol Heart Circ Physiol. October 1, 2000; 279 (4): H1748-56.

A constitutively open potassium channel formed by KCNQ1 and KCNE3., Schroeder BC, Waldegger S, Fehr S, Bleich M, Warth R, Greger R, Jentsch TJ., Nature. January 13, 2000; 403 (6766): 196-9.

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