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Summary Expression Phenotypes Gene Literature (42) GO Terms (6) Nucleotides (135) Proteins (80) Interactants (58) Wiki
XB-GENEPAGE-984128

Papers associated with slc8a1



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Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger., Li Z, Matsuoka S, Hryshko LV, Nicoll DA, Bersohn MM, Burke EP, Lifton RP, Philipson KD., J Biol Chem. July 1, 1994; 269 (26): 17434-9.

Anomalous regulation of the Drosophila Na(+)-Ca2+ exchanger by Ca2+., Hryshko LV, Matsuoka S, Nicoll DA, Weiss JN, Schwarz EM, Benzer S, Philipson KD., J Gen Physiol. July 1, 1996; 108 (1): 67-74.

Glass-funnel technique for the recording of membrane currents and intracellular perfusion of Xenopus oocytes., Shuba YM, Naidenov VG, Morad M., Pflugers Arch. July 1, 1996; 432 (3): 562-70.

Unitary cardiac Na+, Ca2+ exchange current magnitudes determined from channel-like noise and charge movements of ion transport., Hilgemann DW., Biophys J. August 1, 1996; 71 (2): 759-68.

Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3., Nicoll DA, Quednau BD, Qui Z, Xia YR, Lusis AJ, Philipson KD., J Biol Chem. October 4, 1996; 271 (40): 24914-21.

Transport and regulation of the cardiac Na(+)-Ca2+ exchanger, NCX1. Comparison between Ca2+ and Ba2+., Trac M, Dyck C, Hnatowich M, Omelchenko A, Hryshko LV., J Gen Physiol. March 1, 1997; 109 (3): 361-9.              

Na+/Ca2+ exchanger in Drosophila: cloning, expression, and transport differences., Ruknudin A, Valdivia C, Kofuji P, Lederer WJ, Schulze DH., Am J Physiol. July 1, 1997; 273 (1 Pt 1): C257-65.

Topology of a functionally important region of the cardiac Na+/Ca2+ exchanger., Doering AE, Nicoll DA, Lu Y, Lu L, Weiss JN, Philipson KD., J Biol Chem. January 9, 1998; 273 (2): 778-83.

Functional differences in ionic regulation between alternatively spliced isoforms of the Na+-Ca2+ exchanger from Drosophila melanogaster., Omelchenko A, Dyck C, Hnatowich M, Buchko J, Nicoll DA, Philipson KD, Hryshko LV., J Gen Physiol. May 1, 1998; 111 (5): 691-702.                  

Structure-function analysis of CALX1.1, a Na+-Ca2+ exchanger from Drosophila. Mutagenesis of ionic regulatory sites., Dyck C, Maxwell K, Buchko J, Trac M, Omelchenko A, Hnatowich M, Hryshko LV., J Biol Chem. May 22, 1998; 273 (21): 12981-7.

Cloning, expression, and characterization of the squid Na+-Ca2+ exchanger (NCX-SQ1)., He Z, Tong Q, Quednau BD, Philipson KD, Hilgemann DW., J Gen Physiol. June 1, 1998; 111 (6): 857-73.                              

Isoform-specific regulation of the Na+/Ca2+ exchanger in rat astrocytes and neurons by PKA., He S, Ruknudin A, Bambrick LL, Lederer WJ, Schulze DH., J Neurosci. July 1, 1998; 18 (13): 4833-41.

A novel molecular determinant for cAMP-dependent regulation of the frog heart Na+-Ca2+ exchanger., Shuba YM, Iwata T, Naidenov VG, Oz M, Sandberg K, Kraev A, Carafoli E, Morad M., J Biol Chem. July 24, 1998; 273 (30): 18819-25.

Molecular study of the Na+/Ca2+ exchanger in bovine adrenal chromaffin cells., Pan CY, Chu YS, Kao LS., Biochem J. December 1, 1998; 336 ( Pt 2) 305-10.

Cloning, expression, and characterization of the trout cardiac Na(+)/Ca(2+) exchanger., Xue XH, Hryshko LV, Nicoll DA, Philipson KD, Tibbits GF., Am J Physiol. October 1, 1999; 277 (4): C693-700.

Ionic regulatory properties of brain and kidney splice variants of the NCX1 Na(+)-Ca(2+) exchanger., Dyck C, Omelchenko A, Elias CL, Quednau BD, Philipson KD, Hnatowich M, Hryshko LV., J Gen Physiol. November 1, 1999; 114 (5): 701-11.                    

Functional role of ionic regulation of Na+/Ca2+ exchange assessed in transgenic mouse hearts., Maxwell K, Scott J, Omelchenko A, Lukas A, Lu L, Lu Y, Hnatowich M, Philipson KD, Hryshko LV., Am J Physiol. December 1, 1999; 277 (6): H2212-21.

A rat kidney-specific calcium transporter in the distal nephron., Peng JB, Chen XZ, Berger UV, Vassilev PM, Brown EM, Hediger MA., J Biol Chem. September 8, 2000; 275 (36): 28186-94.

Functional differences between cardiac and renal isoforms of the rat Na+-Ca2+ exchanger NCX1 expressed in Xenopus oocytes., Ruknudin A, He S, Lederer WJ, Schulze DH., J Physiol. December 15, 2000; 529 Pt 3 (Pt 3): 599-610.

Inhibition of Na+/Ca2+ exchange by KB-R7943: transport mode selectivity and antiarrhythmic consequences., Elias CL, Lukas A, Shurraw S, Scott J, Omelchenko A, Gross GJ, Hnatowich M, Hryshko LV., Am J Physiol Heart Circ Physiol. September 1, 2001; 281 (3): H1334-45.

Temperature dependence of cloned mammalian and salmonid cardiac Na(+)/Ca(2+) exchanger isoforms., Elias CL, Xue XH, Marshall CR, Omelchenko A, Hryshko LV, Tibbits GF., Am J Physiol Cell Physiol. September 1, 2001; 281 (3): C993-C1000.

A disulfide bond is required for functional assembly of NCX1 from complementary fragments., Qiu Z, Chen J, Nicoll DA, Philipson KD., Biochem Biophys Res Commun. October 5, 2001; 287 (4): 825-8.

Expression of Na(+)/Ca(2+) exchanger isoforms (NCX1 and NCX3) and plasma membrane Ca(2+) ATPase during osteoblast differentiation., Stains JP, Weber JA, Gay CV., J Cell Biochem. January 1, 2002; 84 (3): 625-35.

Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor., Müller JG, Thompson JT, Edmonson AM, Rackley MS, Kasahara H, Izumo S, McQuinn TC, Menick DR, O'Brien TX., J Mol Cell Cardiol. July 1, 2002; 34 (7): 807-21.

The molecular determinants of ionic regulatory differences between brain and kidney Na+/Ca2+ exchanger (NCX1) isoforms., Dunn J, Elias CL, Le HD, Omelchenko A, Hryshko LV, Lytton J., J Biol Chem. September 13, 2002; 277 (37): 33957-62.

Kinetic model of transport and regulation of the cardiac, brain, and kidney isoforms of NCX1., Omelchenko A, Elias CL, Scatliff R, Choptiany P, Hnatowich M, Hryshko LV., Ann N Y Acad Sci. November 1, 2002; 976 205-8.

Functional regulation of alternatively spliced Na+/Ca2+ exchanger (NCX1) isoforms., Schulze DH, Polumuri SK, Gille T, Ruknudin A., Ann N Y Acad Sci. November 1, 2002; 976 187-96.

Tissue-specific modes of Na/Ca exchanger regulation., Hryshko LV., Ann N Y Acad Sci. November 1, 2002; 976 166-75.

Molecular determinants of cAMP-mediated regulation of the Na+-Ca2+ exchanger expressed in human cell lines., He LP, Cleemann L, Soldatov NM, Morad M., J Physiol. May 1, 2003; 548 (Pt 3): 677-89.

Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation., Bouchard R, Omelchenko A, Le HD, Choptiany P, Matsuda T, Baba A, Takahashi K, Nicoll DA, Philipson KD, Hnatowich M, Hryshko LV., Mol Pharmacol. March 1, 2004; 65 (3): 802-10.

Inhibitory profile of SEA0400 [2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline] assessed on the cardiac Na+-Ca2+ exchanger, NCX1.1., Lee C, Lee C, Visen NS, Dhalla NS, Le HD, Isaac M, Choptiany P, Gross G, Omelchenko A, Matsuda T, Baba A, Takahashi K, Hnatowich M, Hryshko LV., J Pharmacol Exp Ther. November 1, 2004; 311 (2): 748-57.

Cross-talk between native plasmalemmal Na+/Ca2+ exchanger and inositol 1,4,5-trisphosphate-sensitive ca2+ internal store in Xenopus oocytes., Solís-Garrido LM, Pintado AJ, Andrés-Mateos E, Figueroa M, Matute C, Montiel C., J Biol Chem. December 10, 2004; 279 (50): 52414-24.

Allosteric activation of sodium-calcium exchange by picomolar concentrations of cadmium., Le HD, Omelchenko A, Hryshko LV, Uliyanova A, Condrescu M, Reeves JP., J Physiol. February 15, 2005; 563 (Pt 1): 105-17.

cDNA cloning and expression of the cardiac Na+/Ca2+ exchanger from Mozambique tilapia (Oreochromis mossambicus) reveal a teleost membrane transporter with mammalian temperature dependence., Marshall CR, Pan TC, Le HD, Omelchenko A, Hwang PP, Hryshko LV, Tibbits GF., J Biol Chem. August 12, 2005; 280 (32): 28903-11.

Frequency-dependent regulation of cardiac Na(+)/Ca(2+) exchanger., Omelchenko A, Bouchard R, Shurraw S, Trac M, Hnatowich M, Hryshko LV., Am J Physiol Heart Circ Physiol. October 1, 2005; 289 (4): H1594-603.

Fluorescent Na+-Ca+ exchangers: electrophysiological and optical characterization., Ottolia M, John S, Ren X, Philipson KD., J Biol Chem. February 9, 2007; 282 (6): 3695-701.

Time resolved kinetics of the guinea pig Na-Ca exchanger (NCX1) expressed in Xenopus oocytes: voltage and Ca(2+) dependence of pre-steady-state current investigated by photolytic Ca (2+)concentration jumps., Haase A, Wood PG, Pintschovius V, Bamberg E, Hartung K., Pflugers Arch. September 1, 2007; 454 (6): 1031-42.

Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.                                                                        

Pre-steady-state kinetics of Ba-Ca exchange reveals a second electrogenic step involved in Ca2+ translocation by the Na-Ca exchanger., Haase A, Hartung K., Biophys J. June 3, 2009; 96 (11): 4571-80.

μ-Calpain-mediated deregulation of cardiac, brain, and kidney NCX1 splice variants., Hnatowich M, Le HD, DeMoissac D, Ranson K, Yurkov V, Gilchrist JS, Omelchenko A, Hryshko LV., Cell Calcium. February 1, 2012; 51 (2): 164-70.

The cardiac Na+-Ca2+ exchanger has two cytoplasmic ion permeation pathways., John SA, Liao J, Jiang Y, Ottolia M., Proc Natl Acad Sci U S A. April 30, 2013; 110 (18): 7500-5.

Molecular determinants of pH regulation in the cardiac Na+-Ca2+ exchanger., John S, Kim B, Olcese R, Goldhaber JI, Ottolia M., J Gen Physiol. February 5, 2018; 150 (2): 245-257.                  

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