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Summary Expression Phenotypes Gene Literature (177) GO Terms (0) Nucleotides (44) Proteins (32) Interactants (264) Wiki
XB-GENEPAGE-985558

Papers associated with kcnh1



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referenced by:

Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP., Brüggemann A, Pardo LA, Stühmer W, Pongs O., Nature. September 30, 1993; 365 (6445): 445-8.

Functional expression of a rat homologue of the voltage gated either á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart., Ludwig J, Terlau H, Wunder F, Brüggemann A, Pardo LA, Marquardt A, Stühmer W, Pongs O., EMBO J. October 3, 1994; 13 (19): 4451-8.

Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes., Robertson GA, Warmke JM, Ganetzky B., Neuropharmacology. January 1, 1996; 35 (7): 841-50.

Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole., Suessbrich H, Waldegger S, Lang F, Busch AE., FEBS Lett. April 29, 1996; 385 (1-2): 77-80.

Extracellular Mg2+ regulates activation of rat eag potassium channel., Terlau H, Ludwig J, Steffan R, Pongs O, Stühmer W, Heinemann SH., Pflugers Arch. June 1, 1996; 432 (2): 301-12.

Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel., Schönherr R, Heinemann SH., J Physiol. June 15, 1996; 493 ( Pt 3) 635-42.

HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine., Roy M, Dumaine R, Brown AM., Circulation. August 15, 1996; 94 (4): 817-23.

Heteromultimeric interactions among K+ channel subunits from Shaker and eag families in Xenopus oocytes., Chen ML, Hoshi T, Wu CF., Neuron. September 1, 1996; 17 (3): 535-42.

Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide., Kiehn J, Lacerda AE, Wible B, Brown AM., Circulation. November 15, 1996; 94 (10): 2572-9.

Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes., Brüggemann A, Stühmer W, Pardo LA., Proc Natl Acad Sci U S A. January 21, 1997; 94 (2): 537-42.

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes., Suessbrich H, Schönherr R, Heinemann SH, Attali B, Lang F, Busch AE., Br J Pharmacol. March 1, 1997; 120 (5): 968-74.

Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment., Terlau H, Heinemann SH, Stühmer W, Pongs O, Ludwig J., J Physiol. August 1, 1997; 502 ( Pt 3) 537-43.

Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241., Suessbrich H, Schönherr R, Heinemann SH, Lang F, Busch AE., FEBS Lett. September 8, 1997; 414 (2): 435-8.

Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current., London B, Trudeau MC, Newton KP, Beyer AK, Copeland NG, Gilbert DJ, Jenkins NA, Satler CA, Robertson GA., Circ Res. November 1, 1997; 81 (5): 870-8.

Influence of detergents on the function of cloned potassium channels., Höllerer-Beitz G, Heinemann SH., Recept Channels. January 1, 1998; 5 (2): 61-78.

herg encodes a K+ current highly conserved in tumors of different histogenesis: a selective advantage for cancer cells?, Bianchi L, Wible B, Arcangeli A, Taglialatela M, Morra F, Castaldo P, Crociani O, Rosati B, Faravelli L, Olivotto M, Wanke E., Cancer Res. February 15, 1998; 58 (4): 815-22.

Interaction of the K channel beta subunit, Hyperkinetic, with eag family members., Wilson GF, Wang Z, Chouinard SW, Griffith LC, Ganetzky B., J Biol Chem. March 13, 1998; 273 (11): 6389-94.

Voltage-dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca2+ and Mg2+., Ho WK, Kim I, Lee CO, Lee CO, Earm YE., J Physiol. March 15, 1998; 507 ( Pt 3) (Pt 3): 631-8.

A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation., Zou A, Xu QP, Sanguinetti MC., J Physiol. May 15, 1998; 509 ( Pt 1) 129-37.

Shaker and ether-à-go-go K+ channel subunits fail to coassemble in Xenopus oocytes., Tang CY, Schulteis CT, Jiménez RM, Papazian DM., Biophys J. September 1, 1998; 75 (3): 1263-70.

KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels., Hoshi N, Takahashi H, Shahidullah M, Yokoyama S, Higashida H., J Biol Chem. September 4, 1998; 273 (36): 23080-5.

Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia., Shi W, Wang HS, Pan Z, Wymore RS, Cohen IS, McKinnon D, Dixon JE., J Physiol. September 15, 1998; 511 ( Pt 3) (Pt 3): 675-82.

Cell cycle-related changes in the conducting properties of r-eag K+ channels., Pardo LA, Brüggemann A, Camacho J, Stühmer W., J Cell Biol. November 2, 1998; 143 (3): 767-75.                

Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations., Ho WK, Kim I, Lee CO, Lee CO, Youm JB, Lee SH, Earm YE., Biophys J. April 1, 1999; 76 (4): 1959-71.

Functional analysis of a mouse brain Elk-type K+ channel., Trudeau MC, Titus SA, Branchaw JL, Ganetzky B, Robertson GA., J Neurosci. April 15, 1999; 19 (8): 2906-18.

Blockade of HERG channels expressed in Xenopus oocytes by external H+., Jo SH, Youm JB, Kim I, Lee CO, Lee CO, Earm YE, Ho WK., Pflugers Arch. June 1, 1999; 438 (1): 23-9.

Proton and zinc effects on HERG currents., Anumonwo JM, Horta J, Delmar M, Taffet SM, Jalife J., Biophys J. July 1, 1999; 77 (1): 282-98.

Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2., Nakajima T, Furukawa T, Hirano Y, Tanaka T, Sakurada H, Takahashi T, Nagai R, Itoh T, Katayama Y, Nakamura Y, Hiraoka M., Cardiovasc Res. November 1, 1999; 44 (2): 283-93.

Purification of an EH domain-binding protein from rat brain that modulates the gating of the rat ether-à-go-go channel., Piros ET, Shen L, Huang XY., J Biol Chem. November 19, 1999; 274 (47): 33677-83.

Cloning of components of a novel subthreshold-activating K(+) channel with a unique pattern of expression in the cerebral cortex., Saganich MJ, Vega-Saenz de Miera E, Nadal MS, Baker H, Coetzee WA, Rudy B., J Neurosci. December 15, 1999; 19 (24): 10789-802.

Extracellular Mg(2+) modulates slow gating transitions and the opening of Drosophila ether-à-Go-Go potassium channels., Tang CY, Bezanilla F, Papazian DM., J Gen Physiol. March 1, 2000; 115 (3): 319-38.                            

Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline., Jo SH, Youm JB, Lee CO, Lee CO, Earm YE, Ho WK., Br J Pharmacol. April 1, 2000; 129 (7): 1474-80.

Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects., Kreutner W, Hey JA, Chiu P, Barnett A., Arzneimittelforschung. May 1, 2000; 50 (5): 441-8.

Altered gating of HERG potassium channels by cobalt and lanthanum., Sanchez-Chapula JA, Sanguinetti MC., Pflugers Arch. June 1, 2000; 440 (2): 264-74.

Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating., Viloria CG, Barros F, Giráldez T, Gómez-Varela D, de la Peña P., Biophys J. July 1, 2000; 79 (1): 231-46.

Sh and eag K(+) channel subunit interaction in frog oocytes depends on level and time of expression., Chen ML, Hoshi T, Wu CF., Biophys J. September 1, 2000; 79 (3): 1358-68.

Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3., Silverman WR, Tang CY, Mock AF, Huh KB, Papazian DM., J Gen Physiol. November 1, 2000; 116 (5): 663-78.                  

Inhibitory effects of berberine on IK1, IK, and HERG channels of cardiac myocytes., Li BX, Yang BF, Zhou J, Xu CQ, Li YR., Acta Pharmacol Sin. February 1, 2001; 22 (2): 125-31.

Antiarrhythmic drug carvedilol inhibits HERG potassium channels., Karle CA, Kreye VA, Thomas D, Röckl K, Kathöfer S, Zhang W, Kiehn J., Cardiovasc Res. February 1, 2001; 49 (2): 361-70.

High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872., Thomas D, Wendt-Nordahl G, Röckl K, Ficker E, Brown AM, Kiehn J., J Pharmacol Exp Ther. May 1, 2001; 297 (2): 753-61.

The S4-S5 linker couples voltage sensing and activation of pacemaker channels., Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC., Proc Natl Acad Sci U S A. September 25, 2001; 98 (20): 11277-82.

Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels., Ficker E, Jarolimek W, Brown AM., Mol Pharmacol. December 1, 2001; 60 (6): 1343-8.

Mapping the receptor site for ergtoxin, a specific blocker of ERG channels., Pardo-López L, García-Valdés J, Gurrola GB, Robertson GA, Possani LD., FEBS Lett. January 2, 2002; 510 (1-2): 45-9.

The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels., Thomas D, Gut B, Wendt-Nordahl G, Kiehn J., J Pharmacol Exp Ther. February 1, 2002; 300 (2): 543-8.

Functional distinction of human EAG1 and EAG2 potassium channels., Schönherr R, Gessner G, Löber K, Heinemann SH., FEBS Lett. March 13, 2002; 514 (2-3): 204-8.

Interactions between S4-S5 linker and S6 transmembrane domain modulate gating of HERG K+ channels., Tristani-Firouzi M, Chen J, Sanguinetti MC., J Biol Chem. May 24, 2002; 277 (21): 18994-9000.

Molecular determinants of voltage-dependent human ether-a-go-go related gene (HERG) K+ channel block., Sánchez-Chapula JA, Navarro-Polanco RA, Culberson C, Chen J, Sanguinetti MC., J Biol Chem. June 28, 2002; 277 (26): 23587-95.

Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels., Park JB, Choe H, Lee YK, Ha KC, Rhee KS, Ko JK, Joo CU, Chae SW, Kwak YG., J Pharmacol Exp Ther. July 1, 2002; 302 (1): 314-9.

Calcium/calmodulin-dependent protein kinase II phosphorylates and regulates the Drosophila eag potassium channel., Wang Z, Wilson GF, Griffith LC., J Biol Chem. July 5, 2002; 277 (27): 24022-9.

Conformational switch between slow and fast gating modes: allosteric regulation of voltage sensor mobility in the EAG K+ channel., Schönherr R, Mannuzzu LM, Isacoff EY, Heinemann SH., Neuron. August 29, 2002; 35 (5): 935-49.

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