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Summary Expression Phenotypes Gene Literature (63) GO Terms (4) Nucleotides (53) Proteins (34) Interactants (60) Wiki
XB-GENEPAGE-991577

Papers associated with kcna3



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Full-length and truncated Kv1.3 K+ channels are modulated by 5-HT1c receptor activation and independently by PKC., Aiyar J, Grissmer S, Chandy KG., Am J Physiol. December 1, 1993; 265 (6 Pt 1): C1571-8.


Chemical synthesis and structure-function studies of margatoxin, a potent inhibitor of voltage-dependent potassium channel in human T lymphocytes., Bednarek MA, Bugianesi RM, Leonard RJ, Felix JP., Biochem Biophys Res Commun. January 28, 1994; 198 (2): 619-25.


Injection of a K+ channel (Kv1.3) cRNA in fertilized eggs leads to functional expression in cultured myotomal muscle cells from Xenopus embryos., Honoré E, Guillemare E, Lesage F, Barhanin J, Lazdunski M., FEBS Lett. July 18, 1994; 348 (3): 259-62.


The P-region and S6 of Kv3.1 contribute to the formation of the ion conduction pathway., Aiyar J, Nguyen AN, Chandy KG, Grissmer S., Biophys J. December 1, 1994; 67 (6): 2261-4.


Stable expression of human Kv1.3 potassium channels resets the resting membrane potential of cultured mammalian cells., Defarias FP, Stevens SP, Leonard RJ., Recept Channels. January 1, 1995; 3 (4): 273-81.


Truncated K+ channel DNA sequences specifically suppress lymphocyte K+ channel gene expression., Tu L, Santarelli V, Deutsch C., Biophys J. January 1, 1995; 68 (1): 147-56.


Susceptibility of cloned K+ channels to reactive oxygen species., Duprat F, Guillemare E, Romey G, Fink M, Lesage F, Lazdunski M, Honore E., Proc Natl Acad Sci U S A. December 5, 1995; 92 (25): 11796-800.


Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney., Yao X, Chang AY, Boulpaep EL, Segal AS, Desir GV., J Clin Invest. June 1, 1996; 97 (11): 2525-33.


Voltage-gated K+ channels contain multiple intersubunit association sites., Tu L, Santarelli V, Sheng Z, Skach W, Pain D, Deutsch C., J Biol Chem. August 2, 1996; 271 (31): 18904-11.


A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels. Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity., Cotton J, Crest M, Bouet F, Alessandri N, Gola M, Forest E, Karlsson E, Castañeda O, Harvey AL, Vita C, Ménez A., Eur J Biochem. February 15, 1997; 244 (1): 192-202.


Maurotoxin, a four disulfide bridge toxin from Scorpio maurus venom: purification, structure and action on potassium channels., Kharrat R, Mansuelle P, Sampieri F, Crest M, Oughideni R, Van Rietschoten J, Martin-Eauclaire MF, Rochat H, El Ayeb M., FEBS Lett. April 14, 1997; 406 (3): 284-90.


Purification, characterization, and synthesis of three novel toxins from the Chinese scorpion Buthus martensi, which act on K+ channels., Romi-Lebrun R, Lebrun B, Martin-Eauclaire MF, Ishiguro M, Escoubas P, Wu FQ, Hisada M, Pongs O, Nakajima T., Biochemistry. November 4, 1997; 36 (44): 13473-82.


A four-disulphide-bridged toxin, with high affinity towards voltage-gated K+ channels, isolated from Heterometrus spinnifer (Scorpionidae) venom., Lebrun B, Romi-Lebrun R, Martin-Eauclaire MF, Yasuda A, Ishiguro M, Oyama Y, Pongs O, Nakajima T., Biochem J. November 15, 1997; 328 ( Pt 1) 321-7.


Evidence for interaction between transmembrane segments in assembly of Kv1.3., Sheng Z, Skach W, Santarelli V, Deutsch C., Biochemistry. December 9, 1997; 36 (49): 15501-13.


Characterization of a regulatory region in the N-terminus of rabbit kv1.3., Yao X, Huang Y, Kwan HY, Chan P, Segal AS, Desir G., Biochem Biophys Res Commun. August 19, 1998; 249 (2): 492-8.


The effects of Shaker beta-subunits on the human lymphocyte K+ channel Kv1.3., McCormack T, McCormack K, Nadal MS, Vieira E, Ozaita A, Rudy B., J Biol Chem. July 16, 1999; 274 (29): 20123-6.


Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin., Pennington MW, Lanigan MD, Kalman K, Mahnir VM, Rauer H, McVaugh CT, Behm D, Donaldson D, Chandy KG, Kem WR, Norton RS., Biochemistry. November 2, 1999; 38 (44): 14549-58.


Distribution in rat brain of binding sites of kaliotoxin, a blocker of Kv1.1 and Kv1.3 alpha-subunits., Mourre C, Chernova MN, Martin-Eauclaire MF, Bessone R, Jacquet G, Gola M, Alper SL, Crest M., J Pharmacol Exp Ther. December 1, 1999; 291 (3): 943-52.


Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity., Alessandri-Haber N, Lecoq A, Gasparini S, Grangier-Macmath G, Jacquet G, Harvey AL, de Medeiros C, Rowan EG, Gola M, Ménez A, Crest M., J Biol Chem. December 10, 1999; 274 (50): 35653-61.


Regulation of Shaker-type potassium channels by hypoxia. Oxygen-sensitive K+ channels in PC12 cells., Conforti L, Millhorn DE., Adv Exp Med Biol. January 1, 2000; 475 265-74.


Transmembrane biogenesis of Kv1.3., Tu L, Wang J, Helm A, Skach WR, Deutsch C., Biochemistry. February 1, 2000; 39 (4): 824-36.


Close association of the N terminus of Kv1.3 with the pore region., Yao X, Liu W, Tian S, Rafi H, Segal AS, Desir GV., J Biol Chem. April 14, 2000; 275 (15): 10859-63.


Chemical synthesis and characterization of Pi1, a scorpion toxin from Pandinus imperator active on K+ channels., Fajloun Z, Carlier E, Lecomte C, Geib S, Di Luccio E, Bichet D, Mabrouk K, Rochat H, De Waard M, Sabatier JM., Eur J Biochem. August 1, 2000; 267 (16): 5149-55.


Gallamine triethiodide selectively blocks voltage-gated potassium channels in Ranvier nodes., Hinck D, Wulff H, Koppenhöfer E., Gen Physiol Biophys. March 1, 2001; 20 (1): 83-95.


Cloning and expression of three K+ channel cDNAs from Xenopus muscle., Fry M, Paterno G, Moody-Corbett F., Brain Res Mol Brain Res. June 20, 2001; 90 (2): 135-48.          


Dynamic interaction of S5 and S6 during voltage-controlled gating in a potassium channel., Espinosa F, Fleischhauer R, McMahon A, Joho RH., J Gen Physiol. August 1, 2001; 118 (2): 157-70.                  


Pegylation: a method for assessing topological accessibilities in Kv1.3., Lu J, Deutsch C., Biochemistry. November 6, 2001; 40 (44): 13288-301.


Cerebral localization and regulation of the cell volume-sensitive serum- and glucocorticoid-dependent kinase SGK1., Wärntges S, Friedrich B, Henke G, Duranton C, Lang PA, Waldegger S, Meyermann R, Kuhl D, Speckmann EJ, Obermüller N, Witzgall R, Mack AF, Wagner HJ, Wagner A, Bröer S, Lang F., Pflugers Arch. February 1, 2002; 443 (4): 617-24.


Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes., Jespersen T, Grunnet M, Angelo K, Klaerke DA, Olesen SP., Biotechniques. March 1, 2002; 32 (3): 536-8, 540.


Tityustoxin-K(alpha) blockade of the voltage-gated potassium channel Kv1.3., Rodrigues AR, Arantes EC, Monje F, Stühmer W, Varanda WA., Br J Pharmacol. July 1, 2003; 139 (6): 1180-6.


KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels., Grunnet M, Rasmussen HB, Hay-Schmidt A, Rosenstierne M, Klaerke DA, Olesen SP, Jespersen T., Biophys J. September 1, 2003; 85 (3): 1525-37.


Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels., M'Barek S, Mosbah A, Sandoz G, Fajloun Z, Olamendi-Portugal T, Rochat H, Sampieri F, Guijarro JI, Mansuelle P, Delepierre M, De Waard M, Sabatier JM., Eur J Biochem. September 1, 2003; 270 (17): 3583-92.


Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1., Henke G, Maier G, Wallisch S, Boehmer C, Lang F., J Cell Physiol. May 1, 2004; 199 (2): 194-9.


Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels., Yan L, Herrington J, Goldberg E, Dulski PM, Bugianesi RM, Slaughter RS, Banerjee P, Brochu RM, Priest BT, Kaczorowski GJ, Rudy B, Garcia ML., Mol Pharmacol. May 1, 2005; 67 (5): 1513-21.


A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction., Persson AS, Klement G, Almgren M, Sahlholm K, Nilsson J, Petersson S, Arhem P, Schalling M, Lavebratt C., BMC Neurosci. November 23, 2005; 6 65.          


A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily., Abdel-Mottaleb Y, Coronas FV, de Roodt AR, Possani LD, Tytgat J., FEBS Lett. January 23, 2006; 580 (2): 592-6.


Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR., Lange A, Giller K, Hornig S, Martin-Eauclaire MF, Pongs O, Becker S, Baldus M., Nature. April 13, 2006; 440 (7086): 959-62.


Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages., Vicente R, Escalada A, Villalonga N, Texidó L, Roura-Ferrer M, Martín-Satué M, López-Iglesias C, Soler C, Solsona C, Tamkun MM, Felipe A., J Biol Chem. December 8, 2006; 281 (49): 37675-85.


Blockade action of ketanserin and increasing effect of potassium ion on Kv1.3 channels expressed in Xenopus oocytes., Wang X, Liao Y, Zou A, Li L, Tu D., Pharmacol Res. August 1, 2007; 56 (2): 148-54.


The molecular mechanism of toxin-induced conformational changes in a potassium channel: relation to C-type inactivation., Zachariae U, Schneider R, Velisetty P, Lange A, Seeliger D, Wacker SJ, Karimi-Nejad Y, Vriend G, Becker S, Pongs O, Baldus M, de Groot BL., Structure. May 1, 2008; 16 (5): 747-54.


OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae., Abdel-Mottaleb Y, Vandendriessche T, Clynen E, Landuyt B, Jalali A, Vatanpour H, Schoofs L, Tytgat J., Toxicon. June 15, 2008; 51 (8): 1424-30.


Hemitoxin, the first potassium channel toxin from the venom of the Iranian scorpion Hemiscorpius lepturus., Srairi-Abid N, Shahbazzadeh D, Chatti I, Mlayah-Bellalouna S, Mejdoub H, Borchani L, Benkhalifa R, Akbari A, El Ayeb M., FEBS J. September 1, 2008; 275 (18): 4641-50.


A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes., Abbas N, Belghazi M, Abdel-Mottaleb Y, Tytgat J, Bougis PE, Martin-Eauclaire MF., Biochem Biophys Res Commun. November 21, 2008; 376 (3): 525-30.


High extracellular potassium ion concentration attenuates the blockade action of ketanserin on Kv1.3 channels expressed in xenopus oocytes., Liang ZT, Wang XP, Zeng QT, Liao YH, Zou AR, Li L, Tu DN., Chin Med J (Engl). December 20, 2008; 121 (24): 2584-91.


[Effects of telmisartan on voltage-gated Kv1.3 and Kv1.5 potassium channels expressed in Xenopus oocytes]., Li MW, Wang XP, Gao CY, Zou AR., Zhonghua Xin Xue Guan Bing Za Zhi. February 1, 2009; 37 (2): 165-8.


A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library., Takacs Z, Toups M, Kollewe A, Johnson E, Cuello LG, Driessens G, Biancalana M, Koide A, Ponte CG, Perozo E, Gajewski TF, Suarez-Kurtz G, Koide S, Goldstein SA., Proc Natl Acad Sci U S A. December 29, 2009; 106 (52): 22211-6.


A potent potassium channel blocker from Mesobuthus eupeus scorpion venom., Gao B, Peigneur S, Tytgat J, Zhu S., Biochimie. December 1, 2010; 92 (12): 1847-53.


Inhibition of voltage-gated K+ channels in dendritic cells by rapamycin., Tyan L, Sopjani M, Dërmaku-Sopjani M, Schmid E, Yang W, Thi Xuan N, Shumilina E, Lang F., Am J Physiol Cell Physiol. December 1, 2010; 299 (6): C1379-85.


Effect of dextromethorphan on human K(v)1.3 channel activity: involvement of C-type inactivation., Lee JH, Lee JH, Choi SH, Shin TJ, Lee BH, Hwang SH, Kim HC, Nah SY., Eur J Pharmacol. January 25, 2011; 651 (1-3): 122-7.


Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands., Kinoshita M, Matsuoka Y, Suzuki T, Mirrielees J, Yang J., Brain Res. May 3, 2012; 1452 1-9.

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