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Summary Expression Phenotypes Gene Literature (297) GO Terms (6) Nucleotides (86) Proteins (45) Interactants (168) Wiki
XB--1004370

Papers associated with kcnj3



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WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels., An D, Peigneur S, Tytgat J., Biomedicines. April 28, 2021; 9 (5):               


Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation., Rangel-Garcia CI, Salvador C, Chavez-Garcia K, Diaz-Bello B, Lopez-Gonzalez Z, Vazquez-Cruz L, Angel Vazquez-Martinez J, Ortiz-Navarrete V, Riveros-Rosas H, Escobar LI., FEBS Open Bio. January 1, 2021; 11 (4): 1093-1108.            


Hydrogen Sulfide Impairs Meiosis Resumption in Xenopuslaevis Oocytes., Gelaude A, Slaby S, Cailliau K, Marin M, Lescuyer-Rousseau A, Molinaro C, Nevoral J, Kučerová-Chrpová V, Sedmikova M, Petr J, Martoriati A, Bodart JF., Cells. January 1, 2020; 9 (1):                   


Sodium ions allosterically modulate the M2 muscarinic receptor., Friedman S, Tauber M, Ben-Chaim Y., Sci Rep. January 1, 2020; 10 (1): 11177.          


Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism., Ågren R, Zeberg H, Stępniewski TM, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K., ACS Chem Neurosci. January 1, 2020; 11 (19): 3130-3143.            


A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors., Berlin S, Artzy E, Handklo-Jamal R, Kahanovitch U, Parnas H, Dascal N, Yakubovich D., Front Pharmacol. January 1, 2020; 11 1216.                              


Voltage-Dependent Dopamine Potency at D1-Like Dopamine Receptors., Ågren R, Sahlholm K., Front Pharmacol. January 1, 2020; 11 581151.    


Familial Sinus Node Disease Caused by a Gain of GIRK (G-Protein Activated Inwardly Rectifying K+ Channel) Channel Function., Kuß J, Stallmeyer B, Goldstein M, Rinné S, Pees C, Zumhagen S, Seebohm G, Decher N, Pott L, Kienitz MC, Schulze-Bahr E., Circ Genom Precis Med. January 1, 2019; 12 (1): e002238.


Mutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner., Tabak G, Keren-Raifman T, Kahanovitch U, Dascal N., Sci Rep. January 1, 2019; 9 (1): 508.                    


A Photoswitchable Agonist for the Histamine H3 Receptor, a Prototypic Family A G-Protein-Coupled Receptor., Hauwert NJ, Mocking TAM, Da Costa Pereira D, Lion K, Huppelschoten Y, Vischer HF, De Esch IJP, Wijtmans M, Leurs R., Angew Chem Int Ed Engl. January 1, 2019; 58 (14): 4531-4535.        


Non-sedating antihistamines block G-protein-gated inwardly rectifying K+ channels., Chen IS, Liu C, Tateyama M, Karbat I, Uesugi M, Reuveny E, Kubo Y., Br J Pharmacol. January 1, 2019; 176 (17): 3161-3179.


The coupling of the M2 muscarinic receptor to its G protein is voltage dependent., Ben-Chaim Y, Broide C, Parnas H., PLoS One. January 1, 2019; 14 (10): e0224367.          


Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation., Yamada N, Asano Y, Fujita M, Yamazaki S, Inanobe A, Matsuura N, Kobayashi H, Ohno S, Ebana Y, Tsukamoto O, Ishino S, Takuwa A, Kioka H, Yamashita T, Hashimoto N, Zankov DP, Shimizu A, Asakura M, Asanuma H, Kato H, Nishida Y, Miyashita Y, Shinomiya H, Naiki N, Hayashi K, Makiyama T, Ogita H, Miura K, Ueshima H, Komuro I, Yamagishi M, Horie M, Kawakami K, Furukawa T, Koizumi A, Kurachi Y, Sakata Y, Minamino T, Kitakaze M, Takashima S., Circulation. January 1, 2019; 139 (18): 2157-2169.


Point mutation of a conserved aspartate, D69, in the muscarinic M 2  receptor does not modify voltage-sensitive agonist potency., Ågren R, Sahlholm K, Nilsson J, Århem P., Biochem Biophys Res Commun. January 1, 2018; 496 (1): 101-104.  


The Beta-Arrestin-Biased Dopamine D2 Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation., Ågren R, Århem P, Nilsson J, Sahlholm K., Int J Neuropsychopharmacol. January 1, 2018; 21 (12): 1102-1108.    


Ivermectin activates GIRK channels in a PIP2 -dependent, Gβγ -independent manner and an amino acid residue at the slide helix governs the activation., Chen IS, Tateyama M, Fukata Y, Uesugi M, Kubo Y., J Physiol. September 1, 2017; 595 (17): 5895-5912.


A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction., Stallmeyer B, Kuß J, Kotthoff S, Zumhagen S, Vowinkel K, Rinné S, Matschke LA, Friedrich C, Schulze-Bahr E, Rust S, Seebohm G, Decher N, Schulze-Bahr E., Circ Res. May 12, 2017; 120 (10): e33-e44.


Cholesterol up-regulates neuronal G protein-gated inwardly rectifying potassium (GIRK) channel activity in the hippocampus., Bukiya AN, Durdagi S, Noskov S, Rosenhouse-Dantsker A., J Biol Chem. January 1, 2017; 292 (15): 6135-6147.


Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity., Chen IS, Furutani K, Kurachi Y., Sci Rep. January 1, 2017; 7 (1): 6110.          


Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors., Levitz J, Habrian C, Bharill S, Fu Z, Vafabakhsh R, Isacoff EY., Neuron. October 5, 2016; 92 (1): 143-159.                                  


Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells., Baki L, Fribourg M, Younkin J, Eltit JM, Moreno JL, Park G, Vysotskaya Z, Narahari A, Sealfon SC, Gonzalez-Maeso J, Logothetis DE., Pflugers Arch. May 1, 2016; 468 (5): 775-93.


Mitragynine and its potential blocking effects on specific cardiac potassium channels., Tay YL, Teah YF, Chong YM, Jamil MFA, Kollert S, Adenan MI, Wahab HA, Döring F, Wischmeyer E, Tan ML., Toxicol Appl Pharmacol. January 1, 2016; 305 22-39.


GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin., Hablitz LM, Molzof HE, Abrahamsson KE, Cooper JM, Prosser RA, Gamble KL., J Neurosci. November 11, 2015; 35 (45): 14957-65.


A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ., Yakubovich D, Berlin S, Kahanovitch U, Rubinstein M, Farhy-Tselnicker I, Styr B, Keren-Raifman T, Dessauer CW, Dascal N., PLoS Comput Biol. November 1, 2015; 11 (11): e1004598.                  


Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1., Kahanovitch U, Tsemakhovich V, Berlin S, Rubinstein M, Styr B, Castel R, Peleg S, Tabak G, Dessauer CW, Ivanina T, Dascal N., J Physiol. December 15, 2014; 592 (24): 5373-90.


Dual regulation of G proteins and the G-protein-activated K+ channels by lithium., Farhy Tselnicker I, Tsemakhovich V, Rishal I, Kahanovitch U, Dessauer CW, Dascal N., Proc Natl Acad Sci U S A. April 1, 2014; 111 (13): 5018-23.


RGS4 regulates partial agonism of the M2 muscarinic receptor-activated K+ currents., Chen IS, Furutani K, Inanobe A, Kurachi Y., J Physiol. March 15, 2014; 592 (6): 1237-48.            


Differential effects of genetically-encoded Gβγ scavengers on receptor-activated and basal Kir3.1/Kir3.4 channel current in rat atrial myocytes., Kienitz MC, Mintert-Jancke E, Hertel F, Pott L., Cell Signal. February 24, 2014; 26 (6): 1182-1192.


G protein-coupled receptor signaling to Kir channels in Xenopus oocytes., Hatcher-Solis C, Fribourg M, Spyridaki K, Younkin J, Ellaithy A, Xiang G, Liapakis G, Gonzalez-Maeso J, Zhang H, Cui M, Logothetis DE., Curr Pharm Biotechnol. January 1, 2014; 15 (10): 987-95.


Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4., Guyon A, Kussrow A, Olmsted IR, Sandoz G, Bornhop DJ, Nahon JL., J Neurosci. July 10, 2013; 33 (28): 11643-54.


Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase., Treiber F, Rosker C, Keren-Raifman T, Steinecker B, Gorischek A, Dascal N, Schreibmayer W., Biochim Biophys Acta. April 1, 2013; 1828 (4): 1214-21.              


The polarization of the G-protein activated potassium channel GIRK5 to the vegetal pole of Xenopus laevis oocytes is driven by a di-leucine motif., Díaz-Bello B, Rangel-García CI, Salvador C, Carrisoza-Gaytán R, Escobar LI., PLoS One. January 1, 2013; 8 (5): e64096.                


Voltage affects the dissociation rate constant of the m2 muscarinic receptor., Ben Chaim Y, Bochnik S, Parnas I, Parnas H., PLoS One. January 1, 2013; 8 (9): e74354.          


Voltage sensitivities and deactivation kinetics of histamine H₃ and H₄ receptors., Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P., Biochim Biophys Acta. December 1, 2012; 1818 (12): 3081-9.


RGS proteins maintain robustness of GPCR-GIRK coupling by selective stimulation of the G protein subunit Gαo., Chuang HH, Chuang AY., Sci Signal. February 21, 2012; 5 (212): ra15.


Engineering of an artificial light-modulated potassium channel., Caro LN, Moreau CJ, Estrada-Mondragón A, Ernst OP, Vivaudou M., PLoS One. January 1, 2012; 7 (8): e43766.          


The role of RGS protein in agonist-dependent relaxation of GIRK currents in Xenopus oocytes., Sahlholm K., Biochem Biophys Res Commun. November 25, 2011; 415 (3): 509-14.


The clozapine metabolite N-desmethylclozapine displays variable activity in diverse functional assays at human dopamine D₂ and serotonin 5-HT₁A receptors., Heusler P, Bruins Slot L, Tourette A, Tardif S, Cussac D., Eur J Pharmacol. November 1, 2011; 669 (1-3): 51-8.


Agonist-specific voltage sensitivity at the dopamine D2S receptor--molecular determinants and relevance to therapeutic ligands., Sahlholm K, Barchad-Avitzur O, Marcellino D, Gómez-Soler M, Fuxe K, Ciruela F, Arhem P., Neuropharmacology. October 1, 2011; 61 (5-6): 937-49.


Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium., Whorton MR, MacKinnon R., Cell. September 30, 2011; 147 (1): 199-208.


Two distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunits., Berlin S, Tsemakhovich VA, Castel R, Ivanina T, Dessauer CW, Keren-Raifman T, Dascal N., J Biol Chem. September 23, 2011; 286 (38): 33223-35.


Hesperidin induces antinociceptive effect in mice and its aglycone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents., Loscalzo LM, Yow TT, Wasowski C, Chebib M, Marder M., Pharmacol Biochem Behav. September 1, 2011; 99 (3): 333-41.


β2-Adrenergic ion-channel coupled receptors as conformational motion detectors., Caro LN, Moreau CJ, Revilloud J, Vivaudou M., PLoS One. March 2, 2011; 6 (3): e18226.            


Inhibition of g protein-activated inwardly rectifying k channels by phencyclidine., Kobayashi T, Nishizawa D, Ikeda K., Curr Neuropharmacol. March 1, 2011; 9 (1): 244-6.    


Identification of selective agonists and antagonists to g protein-activated inwardly rectifying potassium channels: candidate medicines for drug dependence and pain., Nishizawa D, Gajya N, Ikeda K., Curr Neuropharmacol. March 1, 2011; 9 (1): 113-7.      


Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5)., Poparic I, Schreibmayer W, Schoser B, Desoye G, Gorischek A, Miedl H, Hochmeister S, Binder J, Quasthoff S, Wagner K, Windpassinger C, Malle E., PLoS One. January 1, 2011; 6 (10): e26524.            


Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants., Kobayashi T, Washiyama K, Ikeda K., PLoS One. January 1, 2011; 6 (12): e28208.            


Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1., Raphemot R, Lonergan DF, Nguyen TT, Utley T, Lewis LM, Kadakia R, Weaver CD, Gogliotti R, Hopkins C, Lindsley CW, Denton JS., Front Pharmacol. January 1, 2011; 2 75.              


G protein {beta}{gamma} gating confers volatile anesthetic inhibition to Kir3 channels., Styer AM, Mirshahi UL, Wang C, Girard L, Jin T, Logothetis DE, Mirshahi T., J Biol Chem. December 31, 2010; 285 (53): 41290-9.


Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers., Leal-Pinto E, Gómez-Llorente Y, Sundaram S, Tang QY, Ivanova-Nikolova T, Mahajan R, Baki L, Zhang Z, Chavez J, Ubarretxena-Belandia I, Logothetis DE., J Biol Chem. December 17, 2010; 285 (51): 39790-800.

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