Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (86) GO Terms (10) Nucleotides (419) Proteins (51) Interactants (322) Wiki
XB--1014887

Papers associated with cdt1



???displayGene.coCitedPapers???
2 ???displayGene.morpholinoPapers???

???pagination.result.count???

???pagination.result.page??? 1 2 ???pagination.result.next???

Sort Newest To Oldest Sort Oldest To Newest

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders., Kaiyrzhanov R, Rad A, Lin SJ, Bertoli-Avella A, Kallemeijn WW, Godwin A, Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Karimiani EG, Hempel M, Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi JR, Ganieva M, Fowler B, Aanicai R, Tayfun GA, Al Saman A, Alswaid A, Amiri N, Asilova N, Shotelersuk V, Yeetong P, Azam M, Babaei M, Monajemi GB, Mohammadi P, Samie S, Banu SH, Pinto Basto J, Kortüm F, Bauer M, Bauer P, Beetz C, Garshasbi M, Issa AH, Eyaid W, Ahmed H, Hashemi N, Hassanpour K, Herman I, Ibrohimov S, Abdul-Majeed BA, Imdad M, Isrofilov M, Kaiyal Q, Khan S, Kirmse B, Koster J, Lourenço CM, Mitani T, Moldovan O, Murphy D, Najafi M, Pehlivan D, Rocha ME, Salpietro V, Schmidts M, Shalata A, Mahroum M, Talbeya JK, Taylor RW, Vazquez D, Vetro A, Waterham HR, Zaman M, Schrader TA, Chung WK, Guerrini R, Lupski JR, Gleeson J, Suri M, Jamshidi Y, Bhatia KP, Vona B, Schrader M, Severino M, Guille M, Tate EW, Varshney GK, Houlden H, Maroofian R., Brain. April 4, 2024; 147 (4): 1436-1456.                            

The cohesin modifier ESCO2 is stable during DNA replication., Jevitt AM, Rankin BD, Chen J, Rankin S., Chromosome Res. January 28, 2023; 31 (1): 6.        

Studying chromosome biology with single-molecule resolution in Xenopus laevis egg extracts., Cameron G, Yardimci H., Essays Biochem. April 16, 2021; 65 (1): 17-26.        

MCM interference during licensing of DNA replication in Xenopus egg extracts-Possible Role of a C-terminal region of MCM3., Mimura S, Kubota Y, Takisawa H., Cell Cycle. January 1, 2018; 17 (4): 492-505.

Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance., Ishiyama S, Nishiyama A, Saeki Y, Moritsugu K, Morimoto D, Yamaguchi L, Arai N, Matsumura R, Kawakami T, Mishima Y, Hojo H, Shimamura S, Ishikawa F, Tajima S, Tanaka K, Ariyoshi M, Shirakawa M, Ikeguchi M, Kidera A, Suetake I, Arita K, Nakanishi M., Mol Cell. October 19, 2017; 68 (2): 350-360.e7.            

Mutant analysis of Cdt1's function in suppressing nascent strand elongation during DNA replication in Xenopus egg extracts., Nakazaki Y, Tsuyama T, Azuma Y, Takahashi M, Tada S., Biochem Biophys Res Commun. September 2, 2017; 490 (4): 1375-1380.

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines., Gardner NJ, Gillespie PJ, Carrington JT, Shanks EJ, McElroy SP, Haagensen EJ, Frearson JA, Woodland A, Blow JJ., Cell Chem Biol. August 17, 2017; 24 (8): 981-992.e4.                        

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Rethinking origin licensing., Bell SP., Elife. January 19, 2017; 6   

Characterization of conserved arginine residues on Cdt1 that affect licensing activity and interaction with Geminin or Mcm complex., You Z, Ode KL, Shindo M, Takisawa H, Masai H., Cell Cycle. May 2, 2016; 15 (9): 1213-26.

Excess Cdt1 inhibits nascent strand elongation by repressing the progression of replication forks in Xenopus egg extracts., Nakazaki Y, Tsuyama T, Seki M, Takahashi M, Enomoto T, Tada S., Biochem Biophys Res Commun. February 5, 2016; 470 (2): 405-410.

Studying essential DNA metabolism proteins in Xenopus egg extract., Sannino V, Kolinjivadi AM, Baldi G, Costanzo V., Int J Dev Biol. January 1, 2016; 60 (7-8-9): 221-227.

Thymine DNA glycosylase is a CRL4Cdt2 substrate., Slenn TJ, Morris B, Havens CG, Freeman RM, Takahashi TS, Walter JC., J Biol Chem. August 15, 2014; 289 (33): 23043-23055.

The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing., Caillat C, Pefani DE, Gillespie PJ, Taraviras S, Blow JJ, Lygerou Z, Perrakis A., J Biol Chem. November 1, 2013; 288 (44): 31624-34.                  

Mcm8 and Mcm9 form a dimeric complex in Xenopus laevis egg extract that is not essential for DNA replication initiation., Gambus A, Blow JJ., Cell Cycle. April 15, 2013; 12 (8): 1225-32.                

Early, nonciliary role for microtubule proteins in left-right patterning is conserved across kingdoms., Lobikin M, Wang G, Xu J, Hsieh YW, Chuang CF, Lemire JM, Levin M., Proc Natl Acad Sci U S A. July 31, 2012; 109 (31): 12586-91.                    

Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2., Havens CG, Shobnam N, Guarino E, Centore RC, Zou L, Kearsey SE, Walter JC., J Biol Chem. March 30, 2012; 287 (14): 11410-21.

Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos., Kisielewska J, Blow JJ., Development. January 1, 2012; 139 (1): 63-74.              

Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition., Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ., PLoS One. January 1, 2012; 7 (5): e38009.                        

A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction., Raman M, Havens CG, Walter JC, Harper JW., Mol Cell. October 7, 2011; 44 (1): 72-84.

The midblastula transition defines the onset of Y RNA-dependent DNA replication in Xenopus laevis., Collart C, Christov CP, Smith JC, Krude T., Mol Cell Biol. September 1, 2011; 31 (18): 3857-70.

Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase., Havens CG, Walter JC., Genes Dev. August 1, 2011; 25 (15): 1568-82.

Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing., Ode KL, Fujimoto K, Kubota Y, Takisawa H., Genes Cells. April 1, 2011; 16 (4): 380-96.

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo., Lim JW, Hummert P, Mills JC, Kroll KL., Development. January 1, 2011; 138 (1): 33-44.                    

Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4(Cdt2) -mediated proteolysis., Michishita M, Morimoto A, Ishii T, Komori H, Shiomi Y, Higuchi Y, Nishitani H., Genes Cells. January 1, 2011; 16 (1): 12-22.        

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.              

Replication origins and timing of temporal replication in budding yeast: how to solve the conundrum?, Barberis M, Spiesser TW, Klipp E., Curr Genomics. May 1, 2010; 11 (3): 199-211.          

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication., Evrin C, Clarke P, Zech J, Lurz R, Sun J, Uhle S, Li H, Stillman B, Speck C., Proc Natl Acad Sci U S A. December 1, 2009; 106 (48): 20240-5.

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing., De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 19807-12.

Geminin stabilizes Cdt1 during meiosis in Xenopus oocytes., Narasimhachar Y, Coué M., J Biol Chem. October 2, 2009; 284 (40): 27235-42.

Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2., Havens CG, Walter JC., Mol Cell. July 10, 2009; 35 (1): 93-104.

Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts., Tsuyama T, Watanabe S, Aoki A, Cho Y, Seki M, Enomoto T, Tada S., Mol Biol Cell. February 1, 2009; 20 (3): 937-47.

MCM9 binds Cdt1 and is required for the assembly of prereplication complexes., Lutzmann M, Méchali M., Mol Cell. July 25, 2008; 31 (2): 190-200.

Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts., Takahashi TS, Basu A, Bermudez V, Hurwitz J, Walter JC., Genes Dev. July 15, 2008; 22 (14): 1894-905.            

Geminin is cleaved by caspase-3 during apoptosis in Xenopus egg extracts., Auziol C, Méchali M, Maiorano D., Biochem Biophys Res Commun. September 21, 2007; 361 (2): 276-80.

Geminin prevents rereplication during xenopus development., Kerns SL, Torke SJ, Benjamin JM, McGarry TJ., J Biol Chem. February 23, 2007; 282 (8): 5514-21.

Cdt1 and geminin: role during cell cycle progression and DNA damage in higher eukaryotes., Tada S., Front Biosci. January 1, 2007; 12 1629-41.

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus., Lutzmann M, Maiorano D, Méchali M., EMBO J. December 13, 2006; 25 (24): 5764-74.

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision., Davidson IF, Li A, Blow JJ., Mol Cell. November 3, 2006; 24 (3): 433-43.              

One ring to rule them all? Another cellular responsibility for PCNA., Green CM., Trends Mol Med. October 1, 2006; 12 (10): 455-8.

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1., Jin J, Arias EE, Chen J, Harper JW, Walter JC., Mol Cell. September 1, 2006; 23 (5): 709-21.

Subcellular translocation signals regulate Geminin activity during embryonic development., Boos A, Lee A, Thompson DM, Kroll KL., Biol Cell. June 1, 2006; 98 (6): 363-75.

Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts., Waga S, Zembutsu A., J Biol Chem. April 21, 2006; 281 (16): 10926-34.

Regulation of replication licensing by acetyltransferase Hbo1., Iizuka M, Matsui T, Takisawa H, Smith MM., Mol Cell Biol. February 1, 2006; 26 (3): 1098-108.

PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication., Arias EE, Walter JC., Nat Cell Biol. January 1, 2006; 8 (1): 84-90.

A small gem with great powers: geminin keeps neural progenitors thriving., Aigner S, Gage FH., Dev Cell. August 1, 2005; 9 (2): 171-2.

Geminin regulates neuronal differentiation by antagonizing Brg1 activity., Seo S, Herr A, Lim JW, Richardson GA, Richardson H, Kroll KL., Genes Dev. July 15, 2005; 19 (14): 1723-34.      

Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development., Yanagi K, Mizuno T, Tsuyama T, Tada S, Iida Y, Sugimoto A, Eki T, Enomoto T, Hanaoka F., J Biol Chem. May 20, 2005; 280 (20): 19689-94.

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts., Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.            

Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts., Maiorano D, Krasinska L, Lutzmann M, Mechali M., Curr Biol. January 26, 2005; 15 (2): 146-53.

???pagination.result.page??? 1 2 ???pagination.result.next???